Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50525071'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50525071 (CHEMBL4474634) Show SMILES CCCOc1ccc(NC(=O)C2CCN(C)CC2)cc1-c1nc(CC)c(CC)c(=O)[nH]1 Show InChI InChI=1S/C24H34N4O3/c1-5-14-31-21-9-8-17(25-23(29)16-10-12-28(4)13-11-16)15-19(21)22-26-20(7-3)18(6-2)24(30)27-22/h8-9,15-16H,5-7,10-14H2,1-4H3,(H,25,29)(H,26,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.790	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human PDE5A1 expressed in baculovirus infected sf9 cells using [3H]cGMP as substrate measured after 30 mins by sc...				J Med Chem 62: 4979-4990 (2019) Article DOI: 10.1021/acs.jmedchem.9b00123 BindingDB Entry DOI: 10.7270/Q2T72MWB
					More data for this Ligand-Target Pair