Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM50014097![]() (CHEMBL3260851) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 670 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Inc. Curated by ChEMBL | Assay Description Inhibition of VHL (unknown origin) by fluorescence polarization assay | J Med Chem 63: 7957-7985 (2020) Article DOI: 10.1021/acs.jmedchem.9b01451 BindingDB Entry DOI: 10.7270/Q2QN6BBK | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM50014097![]() (CHEMBL3260851) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of VHL (unknown origin) by fluorescence polarization assay | J Med Chem 62: 5725-5749 (2019) Article DOI: 10.1021/acs.jmedchem.8b01596 BindingDB Entry DOI: 10.7270/Q2QF8X9V | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |