Compile Data Set for Download or QSAR

Found 20 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 10987   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Synaptic vesicle glycoprotein 2A (Rattus norvegicus)	BDBM582018 (US11518754, Compound (R)-3) Show SMILES Cc1cnccc1CN1C[C@H](CC1=O)c1cc(F)c(F)c(F)c1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	0.270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For competition binding experiments, 0.5 mg of the rat brain homogenates in 800 μL of binding buffer (2 mM MgCl2 in 50 mM Tris*HCl, pH=7.4) were...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FN1B15
					More data for this Ligand-Target Pair
Synaptic vesicle glycoprotein 2A (Rattus norvegicus)	BDBM582020 (US11518754, Compound (R)-5) Show SMILES Cc1cnccc1CN1C[C@H](CC1=O)c1cc(F)cc(F)c1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For competition binding experiments, 0.5 mg of the rat brain homogenates in 800 μL of binding buffer (2 mM MgCl2 in 50 mM Tris*HCl, pH=7.4) were...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FN1B15
					More data for this Ligand-Target Pair
Synaptic vesicle glycoprotein 2A (Rattus norvegicus)	BDBM582019 (US11518754, Compound (R)-4) Show SMILES Cc1cnccc1CN1C[C@H](CC1=O)c1ccc(F)c(F)c1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.08	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For competition binding experiments, 0.5 mg of the rat brain homogenates in 800 μL of binding buffer (2 mM MgCl2 in 50 mM Tris*HCl, pH=7.4) were...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FN1B15
					More data for this Ligand-Target Pair
Synaptic vesicle glycoprotein 2A (Rattus norvegicus)	BDBM582022 (US11518754, Compound (R)-12) Show SMILES Fc1cccc(c1)[C@@H]1CN(Cc2ccncc2)C(=O)C1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For competition binding experiments, 0.5 mg of the rat brain homogenates in 800 μL of binding buffer (2 mM MgCl2 in 50 mM Tris*HCl, pH=7.4) were...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FN1B15
					More data for this Ligand-Target Pair
Synaptic vesicle glycoprotein 2A (Rattus norvegicus)	BDBM582021 (US11518754, Compound (R)-11) Show SMILES Cc1cnccc1CN1C[C@H](CC1=O)c1cccc(F)c1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For competition binding experiments, 0.5 mg of the rat brain homogenates in 800 μL of binding buffer (2 mM MgCl2 in 50 mM Tris*HCl, pH=7.4) were...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FN1B15
					More data for this Ligand-Target Pair
Synaptic vesicle glycoprotein 2A (Rattus norvegicus)	BDBM582027 (US11518754, Compound (S)-12) Show SMILES Fc1cccc(c1)[C@H]1CN(Cc2ccncc2)C(=O)C1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For competition binding experiments, 0.5 mg of the rat brain homogenates in 800 μL of binding buffer (2 mM MgCl2 in 50 mM Tris*HCl, pH=7.4) were...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FN1B15
					More data for this Ligand-Target Pair
Synaptic vesicle glycoprotein 2A (Rattus norvegicus)	BDBM582024 (US11518754, Compound (S)-4) Show SMILES Cc1cnccc1CN1C[C@@H](CC1=O)c1ccc(F)c(F)c1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	9.43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For competition binding experiments, 0.5 mg of the rat brain homogenates in 800 μL of binding buffer (2 mM MgCl2 in 50 mM Tris*HCl, pH=7.4) were...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FN1B15
					More data for this Ligand-Target Pair
Synaptic vesicle glycoprotein 2A (Rattus norvegicus)	BDBM582023 (US11518754, Compound (S)-3) Show SMILES Cc1cnccc1CN1C[C@@H](CC1=O)c1cc(F)c(F)c(F)c1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	12.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For competition binding experiments, 0.5 mg of the rat brain homogenates in 800 μL of binding buffer (2 mM MgCl2 in 50 mM Tris*HCl, pH=7.4) were...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FN1B15
					More data for this Ligand-Target Pair
Synaptic vesicle glycoprotein 2A (Rattus norvegicus)	BDBM582026 (US11518754, Compound (S)-11) Show SMILES Cc1cnccc1CN1C[C@@H](CC1=O)c1cccc(F)c1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	18.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For competition binding experiments, 0.5 mg of the rat brain homogenates in 800 μL of binding buffer (2 mM MgCl2 in 50 mM Tris*HCl, pH=7.4) were...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FN1B15
					More data for this Ligand-Target Pair
Synaptic vesicle glycoprotein 2A (Rattus norvegicus)	BDBM582025 (US11518754, Compound (S)-5) Show SMILES Cc1cnccc1CN1C[C@@H](CC1=O)c1cc(F)cc(F)c1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	115	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For competition binding experiments, 0.5 mg of the rat brain homogenates in 800 μL of binding buffer (2 mM MgCl2 in 50 mM Tris*HCl, pH=7.4) were...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FN1B15
					More data for this Ligand-Target Pair
Synaptic vesicle glycoprotein 2A (Rattus norvegicus)	BDBM582018 (US11518754, Compound (R)-3) Show SMILES Cc1cnccc1CN1C[C@H](CC1=O)c1cc(F)c(F)c(F)c1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	1.62	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For competition binding experiments, 0.5 mg of the rat brain homogenates in 800 μL of binding buffer (2 mM MgCl2 in 50 mM Tris*HCl, pH=7.4) were...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FN1B15
					More data for this Ligand-Target Pair
Synaptic vesicle glycoprotein 2A (Rattus norvegicus)	BDBM582020 (US11518754, Compound (R)-5) Show SMILES Cc1cnccc1CN1C[C@H](CC1=O)c1cc(F)cc(F)c1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.52	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For competition binding experiments, 0.5 mg of the rat brain homogenates in 800 μL of binding buffer (2 mM MgCl2 in 50 mM Tris*HCl, pH=7.4) were...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FN1B15
					More data for this Ligand-Target Pair
Synaptic vesicle glycoprotein 2A (Rattus norvegicus)	BDBM582019 (US11518754, Compound (R)-4) Show SMILES Cc1cnccc1CN1C[C@H](CC1=O)c1ccc(F)c(F)c1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For competition binding experiments, 0.5 mg of the rat brain homogenates in 800 μL of binding buffer (2 mM MgCl2 in 50 mM Tris*HCl, pH=7.4) were...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FN1B15
					More data for this Ligand-Target Pair
Synaptic vesicle glycoprotein 2A (Rattus norvegicus)	BDBM582022 (US11518754, Compound (R)-12) Show SMILES Fc1cccc(c1)[C@@H]1CN(Cc2ccncc2)C(=O)C1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For competition binding experiments, 0.5 mg of the rat brain homogenates in 800 μL of binding buffer (2 mM MgCl2 in 50 mM Tris*HCl, pH=7.4) were...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FN1B15
					More data for this Ligand-Target Pair
Synaptic vesicle glycoprotein 2A (Rattus norvegicus)	BDBM582021 (US11518754, Compound (R)-11) Show SMILES Cc1cnccc1CN1C[C@H](CC1=O)c1cccc(F)c1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26.9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For competition binding experiments, 0.5 mg of the rat brain homogenates in 800 μL of binding buffer (2 mM MgCl2 in 50 mM Tris*HCl, pH=7.4) were...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FN1B15
					More data for this Ligand-Target Pair
Synaptic vesicle glycoprotein 2A (Rattus norvegicus)	BDBM582027 (US11518754, Compound (S)-12) Show SMILES Fc1cccc(c1)[C@H]1CN(Cc2ccncc2)C(=O)C1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28.2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For competition binding experiments, 0.5 mg of the rat brain homogenates in 800 μL of binding buffer (2 mM MgCl2 in 50 mM Tris*HCl, pH=7.4) were...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FN1B15
					More data for this Ligand-Target Pair
Synaptic vesicle glycoprotein 2A (Rattus norvegicus)	BDBM582024 (US11518754, Compound (S)-4) Show SMILES Cc1cnccc1CN1C[C@@H](CC1=O)c1ccc(F)c(F)c1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For competition binding experiments, 0.5 mg of the rat brain homogenates in 800 μL of binding buffer (2 mM MgCl2 in 50 mM Tris*HCl, pH=7.4) were...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FN1B15
					More data for this Ligand-Target Pair
Synaptic vesicle glycoprotein 2A (Rattus norvegicus)	BDBM582023 (US11518754, Compound (S)-3) Show SMILES Cc1cnccc1CN1C[C@@H](CC1=O)c1cc(F)c(F)c(F)c1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	75.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For competition binding experiments, 0.5 mg of the rat brain homogenates in 800 μL of binding buffer (2 mM MgCl2 in 50 mM Tris*HCl, pH=7.4) were...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FN1B15
					More data for this Ligand-Target Pair
Synaptic vesicle glycoprotein 2A (Rattus norvegicus)	BDBM582026 (US11518754, Compound (S)-11) Show SMILES Cc1cnccc1CN1C[C@@H](CC1=O)c1cccc(F)c1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	109	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For competition binding experiments, 0.5 mg of the rat brain homogenates in 800 μL of binding buffer (2 mM MgCl2 in 50 mM Tris*HCl, pH=7.4) were...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FN1B15
					More data for this Ligand-Target Pair
Synaptic vesicle glycoprotein 2A (Rattus norvegicus)	BDBM582025 (US11518754, Compound (S)-5) Show SMILES Cc1cnccc1CN1C[C@@H](CC1=O)c1cc(F)cc(F)c1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	698	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For competition binding experiments, 0.5 mg of the rat brain homogenates in 800 μL of binding buffer (2 mM MgCl2 in 50 mM Tris*HCl, pH=7.4) were...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FN1B15
					More data for this Ligand-Target Pair