Compile Data Set for Download or QSAR

Found 61 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50002158   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454197 (CHEMBL4214571) Show SMILES Fc1ccc(F)c(c1)-n1cnc2c(NCc3nc4c(F)c(F)ccc4[nH]3)nc(nc12)N1CCOCC1 Show InChI InChI=1S/C23H18F4N8O/c24-12-1-2-13(25)16(9-12)35-11-29-20-21(32-23(33-22(20)35)34-5-7-36-8-6-34)28-10-17-30-15-4-3-14(26)18(27)19(15)31-17/h1-4,9,11H,5-8,10H2,(H,30,31)(H,28,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454251 (CHEMBL4209917) Show SMILES OCC1CCN(CC1)c1nc(NCc2nc3c(F)c(F)ccc3[nH]2)c2ncn(-c3cccc(F)c3)c2n1 Show InChI InChI=1S/C25H23F3N8O/c26-15-2-1-3-16(10-15)36-13-30-22-23(29-11-19-31-18-5-4-17(27)20(28)21(18)32-19)33-25(34-24(22)36)35-8-6-14(12-37)7-9-35/h1-5,10,13-14,37H,6-9,11-12H2,(H,31,32)(H,29,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454222 (CHEMBL4211222) Show SMILES CN1CCN(CC1)c1ccc(CNc2nc(nc3n(cnc23)-c2cccc(F)c2)N2CCOCC2)nc1 Show InChI InChI=1S/C26H30FN9O/c1-33-7-9-34(10-8-33)22-6-5-20(28-17-22)16-29-24-23-25(32-26(31-24)35-11-13-37-14-12-35)36(18-30-23)21-4-2-3-19(27)15-21/h2-6,15,17-18H,7-14,16H2,1H3,(H,29,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454229 (CHEMBL4203375) Show SMILES Fc1cccc(c1F)-n1cnc2c(NCc3nc4c(F)c(F)ccc4[nH]3)nc(nc12)N1CCOCC1 Show InChI InChI=1S/C23H18F4N8O/c24-12-2-1-3-15(17(12)26)35-11-29-20-21(32-23(33-22(20)35)34-6-8-36-9-7-34)28-10-16-30-14-5-4-13(25)18(27)19(14)31-16/h1-5,11H,6-10H2,(H,30,31)(H,28,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454240 (CHEMBL4218827) Show SMILES Clc1cc2nc(CNc3nc(nc4n(cnc34)-c3cccnc3)N3CCOCC3)[nH]c2cc1Cl Show InChI InChI=1S/C22H19Cl2N9O/c23-14-8-16-17(9-15(14)24)29-18(28-16)11-26-20-19-21(31-22(30-20)32-4-6-34-7-5-32)33(12-27-19)13-2-1-3-25-10-13/h1-3,8-10,12H,4-7,11H2,(H,28,29)(H,26,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454257 (CHEMBL4206247) Show SMILES Fc1ccc2[nH]c(CNc3nc(nc4n(cnc34)-c3ccsc3)N3CCOCC3)nc2c1F Show InChI InChI=1S/C21H18F2N8OS/c22-13-1-2-14-17(16(13)23)27-15(26-14)9-24-19-18-20(31(11-25-18)12-3-8-33-10-12)29-21(28-19)30-4-6-32-7-5-30/h1-3,8,10-11H,4-7,9H2,(H,26,27)(H,24,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454243 (CHEMBL4211301) Show SMILES Fc1cccc(c1)-n1cnc2c(NCc3nc4ccccc4s3)nc(nc12)N1CCOCC1 Show InChI InChI=1S/C23H20FN7OS/c24-15-4-3-5-16(12-15)31-14-26-20-21(25-13-19-27-17-6-1-2-7-18(17)33-19)28-23(29-22(20)31)30-8-10-32-11-9-30/h1-7,12,14H,8-11,13H2,(H,25,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	115	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454231 (CHEMBL4203268) Show SMILES CN1CCN(CC1)c1nc(NCc2nc3c(F)c(F)ccc3[nH]2)c2ncn(-c3ccsc3)c2n1 Show InChI InChI=1S/C22H21F2N9S/c1-31-5-7-32(8-6-31)22-29-20(19-21(30-22)33(12-26-19)13-4-9-34-11-13)25-10-16-27-15-3-2-14(23)17(24)18(15)28-16/h2-4,9,11-12H,5-8,10H2,1H3,(H,27,28)(H,25,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	125	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454214 (CHEMBL4217142) Show SMILES Cc1ccccc1-n1cnc2c(NCc3nc4c(F)c(F)ccc4[nH]3)nc(nc12)N1CCOCC1 Show InChI InChI=1S/C24H22F2N8O/c1-14-4-2-3-5-17(14)34-13-28-21-22(31-24(32-23(21)34)33-8-10-35-11-9-33)27-12-18-29-16-7-6-15(25)19(26)20(16)30-18/h2-7,13H,8-12H2,1H3,(H,29,30)(H,27,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	135	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454256 (CHEMBL4207079) Show SMILES Fc1cc(F)cc(c1)-n1cnc2c(NCc3nc4c(F)c(F)ccc4[nH]3)nc(nc12)N1CCOCC1 Show InChI InChI=1S/C23H18F4N8O/c24-12-7-13(25)9-14(8-12)35-11-29-20-21(32-23(33-22(20)35)34-3-5-36-6-4-34)28-10-17-30-16-2-1-15(26)18(27)19(16)31-17/h1-2,7-9,11H,3-6,10H2,(H,30,31)(H,28,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	145	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454261 (CHEMBL4215691) Show SMILES Fc1cccc(c1)-n1cnc2c(NCc3nc4ccccc4o3)nc(nc12)N1CCOCC1 Show InChI InChI=1S/C23H20FN7O2/c24-15-4-3-5-16(12-15)31-14-26-20-21(25-13-19-27-17-6-1-2-7-18(17)33-19)28-23(29-22(20)31)30-8-10-32-11-9-30/h1-7,12,14H,8-11,13H2,(H,25,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454248 (CHEMBL4211791) Show SMILES Nc1nc(NCc2nc3c(F)c(F)ccc3[nH]2)c2ncn(-c3cccc(F)c3)c2n1 Show InChI InChI=1S/C19H13F3N8/c20-9-2-1-3-10(6-9)30-8-25-16-17(28-19(23)29-18(16)30)24-7-13-26-12-5-4-11(21)14(22)15(12)27-13/h1-6,8H,7H2,(H,26,27)(H3,23,24,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454267 (CHEMBL4206998) Show SMILES Fc1ccc2[nH]c(CNc3nc(nc4n(cnc34)-c3ccccc3C(F)(F)F)N3CCOCC3)nc2c1F Show InChI InChI=1S/C24H19F5N8O/c25-14-5-6-15-19(18(14)26)33-17(32-15)11-30-21-20-22(35-23(34-21)36-7-9-38-10-8-36)37(12-31-20)16-4-2-1-3-13(16)24(27,28)29/h1-6,12H,7-11H2,(H,32,33)(H,30,34,35)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	175	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454218 (CHEMBL4215749) Show SMILES Fc1cccc(c1)-n1cnc2c(NCc3ncc[nH]3)nc(nc12)N1CCOCC1 Show InChI InChI=1S/C19H19FN8O/c20-13-2-1-3-14(10-13)28-12-24-16-17(23-11-15-21-4-5-22-15)25-19(26-18(16)28)27-6-8-29-9-7-27/h1-5,10,12H,6-9,11H2,(H,21,22)(H,23,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	205	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454250 (CHEMBL4204292) Show SMILES COC1CCN(CC1)c1nc(NCc2nc3c(F)c(F)ccc3[nH]2)c2ncn(-c3cccc(F)c3)c2n1 Show InChI InChI=1S/C25H23F3N8O/c1-37-16-7-9-35(10-8-16)25-33-23(29-12-19-31-18-6-5-17(27)20(28)21(18)32-19)22-24(34-25)36(13-30-22)15-4-2-3-14(26)11-15/h2-6,11,13,16H,7-10,12H2,1H3,(H,31,32)(H,29,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	205	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454219 (CHEMBL4215056) Show SMILES OCCNc1nc(NCc2nc3c(F)c(F)ccc3[nH]2)c2ncn(-c3cccc(F)c3)c2n1 Show InChI InChI=1S/C21H17F3N8O/c22-11-2-1-3-12(8-11)32-10-27-18-19(30-21(25-6-7-33)31-20(18)32)26-9-15-28-14-5-4-13(23)16(24)17(14)29-15/h1-5,8,10,33H,6-7,9H2,(H,28,29)(H2,25,26,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	205	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454216 (CHEMBL4210537) Show SMILES Cc1cc(ccn1)-n1cnc2c(NCc3nc4c(F)c(F)ccc4[nH]3)nc(nc12)N1CCOCC1 Show InChI InChI=1S/C23H21F2N9O/c1-13-10-14(4-5-26-13)34-12-28-20-21(31-23(32-22(20)34)33-6-8-35-9-7-33)27-11-17-29-16-3-2-15(24)18(25)19(16)30-17/h2-5,10,12H,6-9,11H2,1H3,(H,29,30)(H,27,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	245	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454234 (CHEMBL4218717) Show SMILES Fc1cc(ccn1)-n1cnc2c(NCc3nc4c(F)c(F)ccc4[nH]3)nc(nc12)N1CCOCC1 Show InChI InChI=1S/C22H18F3N9O/c23-13-1-2-14-18(17(13)25)30-16(29-14)10-27-20-19-21(32-22(31-20)33-5-7-35-8-6-33)34(11-28-19)12-3-4-26-15(24)9-12/h1-4,9,11H,5-8,10H2,(H,29,30)(H,27,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	245	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454230 (CHEMBL4208642) Show SMILES Fc1ccc(c(F)c1)-n1cnc2c(NCc3nc4c(F)c(F)ccc4[nH]3)nc(nc12)N1CCOCC1 Show InChI InChI=1S/C23H18F4N8O/c24-12-1-4-16(14(26)9-12)35-11-29-20-21(32-23(33-22(20)35)34-5-7-36-8-6-34)28-10-17-30-15-3-2-13(25)18(27)19(15)31-17/h1-4,9,11H,5-8,10H2,(H,30,31)(H,28,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454260 (CHEMBL4209206) Show SMILES Clc1cc2nc(CNc3nc(nc4n(cnc34)-c3cccnc3)N3CCNCC3)[nH]c2cc1Cl Show InChI InChI=1S/C22H20Cl2N10/c23-14-8-16-17(9-15(14)24)30-18(29-16)11-27-20-19-21(32-22(31-20)33-6-4-25-5-7-33)34(12-28-19)13-2-1-3-26-10-13/h1-3,8-10,12,25H,4-7,11H2,(H,29,30)(H,27,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	255	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454220 (CHEMBL4211454) Show SMILES Fc1cccc(c1)-n1cnc2c(NCc3nc4c(F)c(F)ccc4[nH]3)nc(nc12)N1CCOCC1 Show InChI InChI=1S/C23H19F3N8O/c24-13-2-1-3-14(10-13)34-12-28-20-21(31-23(32-22(20)34)33-6-8-35-9-7-33)27-11-17-29-16-5-4-15(25)18(26)19(16)30-17/h1-5,10,12H,6-9,11H2,(H,29,30)(H,27,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454223 (CHEMBL4217426) Show SMILES Fc1cccc(c1)-n1cnc2c(NCc3nc4c(F)c(F)ccc4[nH]3)nc(nc12)N1CCC(=O)CC1 Show InChI InChI=1S/C24H19F3N8O/c25-13-2-1-3-14(10-13)35-12-29-21-22(32-24(33-23(21)35)34-8-6-15(36)7-9-34)28-11-18-30-17-5-4-16(26)19(27)20(17)31-18/h1-5,10,12H,6-9,11H2,(H,30,31)(H,28,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	265	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454244 (CHEMBL4210412) Show SMILES Fc1cccc(c1)-n1cnc2c(NCc3nc(c[nH]3)-c3ccccc3)nc(nc12)N1CCOCC1 Show InChI InChI=1S/C25H23FN8O/c26-18-7-4-8-19(13-18)34-16-29-22-23(31-25(32-24(22)34)33-9-11-35-12-10-33)28-15-21-27-14-20(30-21)17-5-2-1-3-6-17/h1-8,13-14,16H,9-12,15H2,(H,27,30)(H,28,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454253 (CHEMBL4205719) Show SMILES CN1CCC(CC1)Nc1nc(NCc2nc3c(F)c(F)ccc3[nH]2)c2ncn(-c3cccc(F)c3)c2n1 Show InChI InChI=1S/C25H24F3N9/c1-36-9-7-15(8-10-36)31-25-34-23(29-12-19-32-18-6-5-17(27)20(28)21(18)33-19)22-24(35-25)37(13-30-22)16-4-2-3-14(26)11-16/h2-6,11,13,15H,7-10,12H2,1H3,(H,32,33)(H2,29,31,34,35)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	305	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454207 (CHEMBL4203904) Show SMILES Fc1cccc(c1)-n1cnc2c(NCc3nc4c(F)c(F)ccc4[nH]3)nc(nc12)N1CCSCC1 Show InChI InChI=1S/C23H19F3N8S/c24-13-2-1-3-14(10-13)34-12-28-20-21(31-23(32-22(20)34)33-6-8-35-9-7-33)27-11-17-29-16-5-4-15(25)18(26)19(16)30-17/h1-5,10,12H,6-9,11H2,(H,29,30)(H,27,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454233 (CHEMBL4218574) Show SMILES CN1CCN(CC1)c1nc(NCc2nc3c(F)c(F)ccc3[nH]2)c2ncn(-c3ccncc3)c2n1 Show InChI InChI=1S/C23H22F2N10/c1-33-8-10-34(11-9-33)23-31-21(20-22(32-23)35(13-28-20)14-4-6-26-7-5-14)27-12-17-29-16-3-2-15(24)18(25)19(16)30-17/h2-7,13H,8-12H2,1H3,(H,29,30)(H,27,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	315	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454221 (CHEMBL4211678) Show SMILES CN1CCN(CC1)c1nc(NCc2nc3cc(Cl)c(Cl)cc3[nH]2)c2ncn(-c3cccnc3)c2n1 Show InChI InChI=1S/C23H22Cl2N10/c1-33-5-7-34(8-6-33)23-31-21(20-22(32-23)35(13-28-20)14-3-2-4-26-11-14)27-12-19-29-17-9-15(24)16(25)10-18(17)30-19/h2-4,9-11,13H,5-8,12H2,1H3,(H,29,30)(H,27,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454241 (CHEMBL4216393) Show SMILES COc1ccc2nc(CNc3nc(nc4n(cnc34)-c3cccnc3)N3CCN(C)CC3)[nH]c2c1 Show InChI InChI=1S/C24H26N10O/c1-32-8-10-33(11-9-32)24-30-22(21-23(31-24)34(15-27-21)16-4-3-7-25-13-16)26-14-20-28-18-6-5-17(35-2)12-19(18)29-20/h3-7,12-13,15H,8-11,14H2,1-2H3,(H,28,29)(H,26,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	335	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454217 (CHEMBL4205151) Show SMILES Fc1cc2nc(CNc3nc(nc4n(cnc34)-c3cccnc3)N3CCOCC3)[nH]c2cc1F Show InChI InChI=1S/C22H19F2N9O/c23-14-8-16-17(9-15(14)24)29-18(28-16)11-26-20-19-21(31-22(30-20)32-4-6-34-7-5-32)33(12-27-19)13-2-1-3-25-10-13/h1-3,8-10,12H,4-7,11H2,(H,28,29)(H,26,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454249 (CHEMBL4212734) Show SMILES Fc1cccc(c1)-n1cnc2c(NCc3nc4c(F)c(F)ccc4[nH]3)nc(nc12)N1CCS(=O)(=O)CC1 Show InChI InChI=1S/C23H19F3N8O2S/c24-13-2-1-3-14(10-13)34-12-28-20-21(27-11-17-29-16-5-4-15(25)18(26)19(16)30-17)31-23(32-22(20)34)33-6-8-37(35,36)9-7-33/h1-5,10,12H,6-9,11H2,(H,29,30)(H,27,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454196 (CHEMBL4213205) Show SMILES Fc1cccc(c1)-n1cnc2c(NCc3nc4c(F)c(F)ccc4[nH]3)nc(NCC3CCOCC3)nc12 Show InChI InChI=1S/C25H23F3N8O/c26-15-2-1-3-16(10-15)36-13-31-22-23(29-12-19-32-18-5-4-17(27)20(28)21(18)33-19)34-25(35-24(22)36)30-11-14-6-8-37-9-7-14/h1-5,10,13-14H,6-9,11-12H2,(H,32,33)(H2,29,30,34,35)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	375	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454245 (CHEMBL4203539) Show SMILES CN1CCN(CC1)c1ccc(CNc2nc(nc3n(cnc23)-c2cccc(F)c2)N2CCOCC2)cc1 Show InChI InChI=1S/C27H31FN8O/c1-33-9-11-34(12-10-33)22-7-5-20(6-8-22)18-29-25-24-26(32-27(31-25)35-13-15-37-16-14-35)36(19-30-24)23-4-2-3-21(28)17-23/h2-8,17,19H,9-16,18H2,1H3,(H,29,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454258 (CHEMBL4206835) Show SMILES Fc1ccc2[nH]c(CNc3nc(nc4n(cnc34)-c3ccncc3)N3CCOCC3)nc2c1F Show InChI InChI=1S/C22H19F2N9O/c23-14-1-2-15-18(17(14)24)29-16(28-15)11-26-20-19-21(31-22(30-20)32-7-9-34-10-8-32)33(12-27-19)13-3-5-25-6-4-13/h1-6,12H,7-11H2,(H,28,29)(H,26,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	385	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454236 (CHEMBL4211128) Show SMILES CN1CCN(CC1)c1nc(NCc2nc3c(F)c(F)ccc3[nH]2)c2ncn(-c3ccnc(C)c3)c2n1 Show InChI InChI=1S/C24H24F2N10/c1-14-11-15(5-6-27-14)36-13-29-21-22(32-24(33-23(21)36)35-9-7-34(2)8-10-35)28-12-18-30-17-4-3-16(25)19(26)20(17)31-18/h3-6,11,13H,7-10,12H2,1-2H3,(H,30,31)(H,28,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	385	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454228 (CHEMBL4213060) Show SMILES Fc1ccc(cc1)-n1cnc2c(NCc3nc4c(F)c(F)ccc4[nH]3)nc(nc12)N1CCOCC1 Show InChI InChI=1S/C23H19F3N8O/c24-13-1-3-14(4-2-13)34-12-28-20-21(31-23(32-22(20)34)33-7-9-35-10-8-33)27-11-17-29-16-6-5-15(25)18(26)19(16)30-17/h1-6,12H,7-11H2,(H,29,30)(H,27,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	395	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454193 (CHEMBL4209644) Show SMILES Fc1ccc2[nH]c(CNc3nc(nc4n(cnc34)-c3cccnc3)N3CCOCC3)nc2c1F Show InChI InChI=1S/C22H19F2N9O/c23-14-3-4-15-18(17(14)24)29-16(28-15)11-26-20-19-21(31-22(30-20)32-6-8-34-9-7-32)33(12-27-19)13-2-1-5-25-10-13/h1-5,10,12H,6-9,11H2,(H,28,29)(H,26,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454259 (CHEMBL4203354) Show SMILES CN1CCN(CC1)c1nc(NCc2nc3cc(Cl)ccc3[nH]2)c2ncn(-c3cccnc3)c2n1 Show InChI InChI=1S/C23H23ClN10/c1-32-7-9-33(10-8-32)23-30-21(26-13-19-28-17-5-4-15(24)11-18(17)29-19)20-22(31-23)34(14-27-20)16-3-2-6-25-12-16/h2-6,11-12,14H,7-10,13H2,1H3,(H,28,29)(H,26,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454254 (CHEMBL4210085) Show SMILES CNC1CCN(CC1)c1nc(NCc2nc3c(F)c(F)ccc3[nH]2)c2ncn(-c3cccc(F)c3)c2n1 Show InChI InChI=1S/C25H24F3N9/c1-29-15-7-9-36(10-8-15)25-34-23(30-12-19-32-18-6-5-17(27)20(28)21(18)33-19)22-24(35-25)37(13-31-22)16-4-2-3-14(26)11-16/h2-6,11,13,15,29H,7-10,12H2,1H3,(H,32,33)(H,30,34,35)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	655	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454242 (CHEMBL4216088) Show SMILES CN1CCN(CC1)c1nc(NCc2nc3cc(F)c(F)cc3[nH]2)c2ncn(-c3cccnc3)c2n1 Show InChI InChI=1S/C23H22F2N10/c1-33-5-7-34(8-6-33)23-31-21(20-22(32-23)35(13-28-20)14-3-2-4-26-11-14)27-12-19-29-17-9-15(24)16(25)10-18(17)30-19/h2-4,9-11,13H,5-8,12H2,1H3,(H,29,30)(H,27,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454213 (CHEMBL4215429) Show SMILES CN1CCN(CC1)c1nc(NCc2nc3c(F)c(F)ccc3[nH]2)c2ncn(-c3ccnc(F)c3)c2n1 Show InChI InChI=1S/C23H21F3N10/c1-34-6-8-35(9-7-34)23-32-21(28-11-17-30-15-3-2-14(24)18(26)19(15)31-17)20-22(33-23)36(12-29-20)13-4-5-27-16(25)10-13/h2-5,10,12H,6-9,11H2,1H3,(H,30,31)(H,28,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454194 (CHEMBL4205223) Show SMILES Clc1ccc2[nH]c(CNc3nc(nc4n(cnc34)-c3cccnc3)N3CCOCC3)nc2c1 Show InChI InChI=1S/C22H20ClN9O/c23-14-3-4-16-17(10-14)28-18(27-16)12-25-20-19-21(30-22(29-20)31-6-8-33-9-7-31)32(13-26-19)15-2-1-5-24-11-15/h1-5,10-11,13H,6-9,12H2,(H,27,28)(H,25,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	715	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454198 (CHEMBL4202462) Show SMILES CN1CCN(CC1)c1nc(NCc2nc3c(F)c(F)ccc3[nH]2)c2ncn(-c3ccc(Cl)nc3)c2n1 Show InChI InChI=1S/C23H21ClF2N10/c1-34-6-8-35(9-7-34)23-32-21(28-11-17-30-15-4-3-14(25)18(26)19(15)31-17)20-22(33-23)36(12-29-20)13-2-5-16(24)27-10-13/h2-5,10,12H,6-9,11H2,1H3,(H,30,31)(H,28,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454269 (CHEMBL4214158) Show SMILES CN1CCN(CC1)c1nc(NCc2nc3c(F)c(F)ccc3[nH]2)c2ncn(-c3ccccn3)c2n1 Show InChI InChI=1S/C23H22F2N10/c1-33-8-10-34(11-9-33)23-31-21(20-22(32-23)35(13-28-20)17-4-2-3-7-26-17)27-12-16-29-15-6-5-14(24)18(25)19(15)30-16/h2-7,13H,8-12H2,1H3,(H,29,30)(H,27,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454239 (CHEMBL4205502) Show SMILES Clc1ccc2[nH]c(CNc3nc(nc4n(cnc34)-c3cccnc3)N3CCNCC3)nc2c1 Show InChI InChI=1S/C22H21ClN10/c23-14-3-4-16-17(10-14)29-18(28-16)12-26-20-19-21(31-22(30-20)32-8-6-24-7-9-32)33(13-27-19)15-2-1-5-25-11-15/h1-5,10-11,13,24H,6-9,12H2,(H,28,29)(H,26,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	915	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454206 (CHEMBL4213254) Show SMILES COc1ccc2nc(CNc3nc(nc4n(cnc34)-c3cccnc3)N3CCOCC3)[nH]c2c1 Show InChI InChI=1S/C23H23N9O2/c1-33-16-4-5-17-18(11-16)28-19(27-17)13-25-21-20-22(30-23(29-21)31-7-9-34-10-8-31)32(14-26-20)15-3-2-6-24-12-15/h2-6,11-12,14H,7-10,13H2,1H3,(H,27,28)(H,25,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	975	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454255 (CHEMBL4216824) Show SMILES Fc1ccc(cc1F)-n1cnc2c(NCc3nc4c(F)c(F)ccc4[nH]3)nc(nc12)N1CCOCC1 Show InChI InChI=1S/C23H18F4N8O/c24-13-2-1-12(9-15(13)26)35-11-29-20-21(32-23(33-22(20)35)34-5-7-36-8-6-34)28-10-17-30-16-4-3-14(25)18(27)19(16)31-17/h1-4,9,11H,5-8,10H2,(H,30,31)(H,28,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454232 (CHEMBL4209759) Show SMILES CN1CCN(CC1)c1nc(NCc2nc3c(F)c(F)ccc3[nH]2)c2ncn(-c3cccnc3)c2n1 Show InChI InChI=1S/C23H22F2N10/c1-33-7-9-34(10-8-33)23-31-21(20-22(32-23)35(13-28-20)14-3-2-6-26-11-14)27-12-17-29-16-5-4-15(24)18(25)19(16)30-17/h2-6,11,13H,7-10,12H2,1H3,(H,29,30)(H,27,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454235 (CHEMBL4215325) Show SMILES Fc1ccc2[nH]c(CNc3nc(nc4n(cnc34)-c3ccc(Cl)nc3)N3CCOCC3)nc2c1F Show InChI InChI=1S/C22H18ClF2N9O/c23-15-4-1-12(9-26-15)34-11-28-19-20(31-22(32-21(19)34)33-5-7-35-8-6-33)27-10-16-29-14-3-2-13(24)17(25)18(14)30-16/h1-4,9,11H,5-8,10H2,(H,29,30)(H,27,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454252 (CHEMBL4207220) Show SMILES CN(C)C1CCN(CC1)c1nc(NCc2nc3c(F)c(F)ccc3[nH]2)c2ncn(-c3cccc(F)c3)c2n1 Show InChI InChI=1S/C26H26F3N9/c1-36(2)16-8-10-37(11-9-16)26-34-24(30-13-20-32-19-7-6-18(28)21(29)22(19)33-20)23-25(35-26)38(14-31-23)17-5-3-4-15(27)12-17/h3-7,12,14,16H,8-11,13H2,1-2H3,(H,32,33)(H,30,34,35)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50454266 (CHEMBL4212477) Show SMILES Fc1cccc(c1)-n1cnc2c(NCc3nc4c(F)c(F)ccc4[nH]3)nc(NCCN3CCOCC3)nc12 Show InChI InChI=1S/C25H24F3N9O/c26-15-2-1-3-16(12-15)37-14-31-22-23(30-13-19-32-18-5-4-17(27)20(28)21(18)33-19)34-25(35-24(22)37)29-6-7-36-8-10-38-11-9-36/h1-5,12,14H,6-11,13H2,(H,32,33)(H2,29,30,34,35)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr13...				Bioorg Med Chem 26: 590-602 (2018) Article DOI: 10.1016/j.bmc.2017.12.020 BindingDB Entry DOI: 10.7270/Q2RR21TZ
					More data for this Ligand-Target Pair

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