Compile Data Set for Download or QSAR

Found 25 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50015401   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155652 (3-Diethylamino-N-[6-(3-diethylamino-propionylamino...) Show SMILES CCN(CC)CCC(=O)Nc1ccc2c(O)c3ccc(NC(=O)CCN(CC)CC)cc3nc2c1 Show InChI InChI=1S/C27H37N5O3/c1-5-31(6-2)15-13-25(33)28-19-9-11-21-23(17-19)30-24-18-20(10-12-22(24)27(21)35)29-26(34)14-16-32(7-3)8-4/h9-12,17-18H,5-8,13-16H2,1-4H3,(H,28,33)(H,29,34)(H,30,35)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155646 (3-(4-Hydroxy-piperidin-1-yl)-N-{6-[3-(4-hydroxy-pi...) Show SMILES OC1CCN(CCC(=O)Nc2ccc3c(O)c4cc(NC(=O)CCN5CCC(O)CC5)ccc4nc3c2)CC1 Show InChI InChI=1S/C29H37N5O5/c35-21-5-11-33(12-6-21)15-9-27(37)30-19-2-4-25-24(17-19)29(39)23-3-1-20(18-26(23)32-25)31-28(38)10-16-34-13-7-22(36)8-14-34/h1-4,17-18,21-22,35-36H,5-16H2,(H,30,37)(H,31,38)(H,32,39)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155654 (3,6,9-Tri-pyrrolidin-1-yl-acridine | CHEMBL184103) Show SMILES C1CCN(C1)c1ccc2c(N3CCCC3)c3ccc(cc3nc2c1)N1CCCC1 Show InChI InChI=1S/C25H30N4/c1-2-12-27(11-1)19-7-9-21-23(17-19)26-24-18-20(28-13-3-4-14-28)8-10-22(24)25(21)29-15-5-6-16-29/h7-10,17-18H,1-6,11-16H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	90	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155650 (3,6-Di-piperidin-1-yl-acridine | CHEMBL187238) Show SMILES C1CCN(CC1)c1ccc2cc3ccc(cc3nc2c1)N1CCCCC1 Show InChI InChI=1S/C23H27N3/c1-3-11-25(12-4-1)20-9-7-18-15-19-8-10-21(26-13-5-2-6-14-26)17-23(19)24-22(18)16-20/h7-10,15-17H,1-6,11-14H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155651 (CHEMBL1081520 | CHEMBL187955 | N-[9-Oxo-6-(3-piper...) Show SMILES Oc1c2ccc(NC(=O)CCN3CCCCC3)cc2nc2cc(NC(=O)CCN3CCCCC3)ccc12 Show InChI InChI=1S/C29H37N5O3/c35-27(11-17-33-13-3-1-4-14-33)30-21-7-9-23-25(19-21)32-26-20-22(8-10-24(26)29(23)37)31-28(36)12-18-34-15-5-2-6-16-34/h7-10,19-20H,1-6,11-18H2,(H,30,35)(H,31,36)(H,32,37)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155661 (3-(4-Methyl-piperidin-1-yl)-N-{6-[3-(4-methyl-pipe...) Show SMILES CC1CCN(CCC(=O)Nc2ccc3c(O)c4cc(NC(=O)CCN5CCC(C)CC5)ccc4nc3c2)CC1 Show InChI InChI=1S/C31H41N5O3/c1-21-7-13-35(14-8-21)17-11-29(37)32-23-4-6-27-26(19-23)31(39)25-5-3-24(20-28(25)34-27)33-30(38)12-18-36-15-9-22(2)10-16-36/h3-6,19-22H,7-18H2,1-2H3,(H,32,37)(H,33,38)(H,34,39)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155662 (3-(2-Hydroxymethyl-piperidin-1-yl)-N-{7-[3-(2-hydr...) Show SMILES OCC1CCCCN1CCC(=O)Nc1ccc2c(O)c3cc(NC(=O)CCN4CCCCC4CO)ccc3nc2c1 Show InChI InChI=1S/C31H41N5O5/c37-19-23-5-1-3-13-35(23)15-11-29(39)32-21-8-10-27-26(17-21)31(41)25-9-7-22(18-28(25)34-27)33-30(40)12-16-36-14-4-2-6-24(36)20-38/h7-10,17-18,23-24,37-38H,1-6,11-16,19-20H2,(H,32,39)(H,33,40)(H,34,41)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155663 (3-(4-Hydroxy-piperidin-1-yl)-N-{6-[3-(4-hydroxy-pi...) Show SMILES OC1CCN(CCC(=O)Nc2ccc3c(O)c4ccc(NC(=O)CCN5CCC(O)CC5)cc4nc3c2)CC1 Show InChI InChI=1S/C29H37N5O5/c35-21-5-11-33(12-6-21)15-9-27(37)30-19-1-3-23-25(17-19)32-26-18-20(2-4-24(26)29(23)39)31-28(38)10-16-34-13-7-22(36)8-14-34/h1-4,17-18,21-22,35-36H,5-16H2,(H,30,37)(H,31,38)(H,32,39)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155659 (3,6-Di-pyrrolidin-1-yl-acridine | CHEMBL186037) Show SMILES C1CCN(C1)c1ccc2cc3ccc(cc3nc2c1)N1CCCC1 Show InChI InChI=1S/C21H23N3/c1-2-10-23(9-1)18-7-5-16-13-17-6-8-19(24-11-3-4-12-24)15-21(17)22-20(16)14-18/h5-8,13-15H,1-4,9-12H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155664 (CHEMBL186994 | N,N,N'',N''-Tetraethyl-acridine-3,6...) Show SMILES CCN(CC)c1ccc2cc3ccc(cc3nc2c1)N(CC)CC Show InChI InChI=1S/C21H27N3/c1-5-23(6-2)18-11-9-16-13-17-10-12-19(24(7-3)8-4)15-21(17)22-20(16)14-18/h9-15H,5-8H2,1-4H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155658 (3-(2-Methyl-piperidin-1-yl)-N-{7-[3-(2-methyl-pipe...) Show SMILES CC1CCCCN1CCC(=O)Nc1ccc2nc3ccc(NC(=O)CCN4CCCCC4C)cc3c(O)c2c1 Show InChI InChI=1S/C31H41N5O3/c1-21-7-3-5-15-35(21)17-13-29(37)32-23-9-11-27-25(19-23)31(39)26-20-24(10-12-28(26)34-27)33-30(38)14-18-36-16-6-4-8-22(36)2/h9-12,19-22H,3-8,13-18H2,1-2H3,(H,32,37)(H,33,38)(H,34,39)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155647 (3-(4-Methyl-piperidin-1-yl)-N-{6-[3-(4-methyl-pipe...) Show SMILES CC1CCN(CCC(=O)Nc2ccc3c(O)c4ccc(NC(=O)CCN5CCC(C)CC5)cc4nc3c2)CC1 Show InChI InChI=1S/C31H41N5O3/c1-21-7-13-35(14-8-21)17-11-29(37)32-23-3-5-25-27(19-23)34-28-20-24(4-6-26(28)31(25)39)33-30(38)12-18-36-15-9-22(2)10-16-36/h3-6,19-22H,7-18H2,1-2H3,(H,32,37)(H,33,38)(H,34,39)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155644 (3-(2-Methyl-piperidin-1-yl)-N-{6-[3-(2-methyl-pipe...) Show SMILES CC1CCCCN1CCC(=O)Nc1ccc2c(O)c3ccc(NC(=O)CCN4CCCCC4C)cc3nc2c1 Show InChI InChI=1S/C31H41N5O3/c1-21-7-3-5-15-35(21)17-13-29(37)32-23-9-11-25-27(19-23)34-28-20-24(10-12-26(28)31(25)39)33-30(38)14-18-36-16-6-4-8-22(36)2/h9-12,19-22H,3-8,13-18H2,1-2H3,(H,32,37)(H,33,38)(H,34,39)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155645 (3-Dimethylamino-N-[7-(3-dimethylamino-propionylami...) Show SMILES CN(C)CCC(=O)Nc1ccc2nc3ccc(NC(=O)CCN(C)C)cc3c(O)c2c1 Show InChI InChI=1S/C23H29N5O3/c1-27(2)11-9-21(29)24-15-5-7-19-17(13-15)23(31)18-14-16(6-8-20(18)26-19)25-22(30)10-12-28(3)4/h5-8,13-14H,9-12H2,1-4H3,(H,24,29)(H,25,30)(H,26,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	600	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155657 (3-(4-Methyl-piperazin-1-yl)-N-{7-[3-(4-methyl-pipe...) Show SMILES CN1CCN(CCC(=O)Nc2ccc3nc4ccc(NC(=O)CCN5CCN(C)CC5)cc4c(O)c3c2)CC1 Show InChI InChI=1S/C29H39N7O3/c1-33-11-15-35(16-12-33)9-7-27(37)30-21-3-5-25-23(19-21)29(39)24-20-22(4-6-26(24)32-25)31-28(38)8-10-36-17-13-34(2)14-18-36/h3-6,19-20H,7-18H2,1-2H3,(H,30,37)(H,31,38)(H,32,39)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155669 (3-Dimethylamino-N-[6-(3-dimethylamino-propionylami...) Show SMILES CN(C)CCC(=O)Nc1ccc2c(O)c3ccc(NC(=O)CCN(C)C)cc3nc2c1 Show InChI InChI=1S/C23H29N5O3/c1-27(2)11-9-21(29)24-15-5-7-17-19(13-15)26-20-14-16(6-8-18(20)23(17)31)25-22(30)10-12-28(3)4/h5-8,13-14H,9-12H2,1-4H3,(H,24,29)(H,25,30)(H,26,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155660 (CHEMBL1079201 | CHEMBL186489 | N-[9-Oxo-7-(3-piper...) Show SMILES Oc1c2cc(NC(=O)CCN3CCCCC3)ccc2nc2ccc(NC(=O)CCN3CCCCC3)cc12 Show InChI InChI=1S/C29H37N5O3/c35-27(11-17-33-13-3-1-4-14-33)30-21-7-9-25-23(19-21)29(37)24-20-22(8-10-26(24)32-25)31-28(36)12-18-34-15-5-2-6-16-34/h7-10,19-20H,1-6,11-18H2,(H,30,35)(H,31,36)(H,32,37)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155667 (CHEMBL1077951 | CHEMBL186019 | N-[9-Oxo-6-(3-piper...) Show SMILES Oc1c2ccc(NC(=O)CCN3CCCCC3)cc2nc2ccc(NC(=O)CCN3CCCCC3)cc12 Show InChI InChI=1S/C29H37N5O3/c35-27(11-17-33-13-3-1-4-14-33)30-21-8-10-25-24(19-21)29(37)23-9-7-22(20-26(23)32-25)31-28(36)12-18-34-15-5-2-6-16-34/h7-10,19-20H,1-6,11-18H2,(H,30,35)(H,31,36)(H,32,37)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155666 (3-(4-Hydroxy-piperidin-1-yl)-N-{7-[3-(4-hydroxy-pi...) Show SMILES OC1CCN(CCC(=O)Nc2ccc3nc4ccc(NC(=O)CCN5CCC(O)CC5)cc4c(O)c3c2)CC1 Show InChI InChI=1S/C29H37N5O5/c35-21-5-11-33(12-6-21)15-9-27(37)30-19-1-3-25-23(17-19)29(39)24-18-20(2-4-26(24)32-25)31-28(38)10-16-34-13-7-22(36)8-14-34/h1-4,17-18,21-22,35-36H,5-16H2,(H,30,37)(H,31,38)(H,32,39)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155648 (3-(2-Ethyl-piperidin-1-yl)-N-{6-[3-(2-ethyl-piperi...) Show SMILES CCC1CCCCN1CCC(=O)Nc1ccc2c(O)c3ccc(NC(=O)CCN4CCCCC4CC)cc3nc2c1 Show InChI InChI=1S/C33H45N5O3/c1-3-25-9-5-7-17-37(25)19-15-31(39)34-23-11-13-27-29(21-23)36-30-22-24(12-14-28(30)33(27)41)35-32(40)16-20-38-18-8-6-10-26(38)4-2/h11-14,21-22,25-26H,3-10,15-20H2,1-2H3,(H,34,39)(H,35,40)(H,36,41)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155653 (CHEMBL1080791 | CHEMBL185975 | N-[9-Oxo-6-(3-pyrro...) Show SMILES Oc1c2ccc(NC(=O)CCN3CCCC3)cc2nc2cc(NC(=O)CCN3CCCC3)ccc12 Show InChI InChI=1S/C27H33N5O3/c33-25(9-15-31-11-1-2-12-31)28-19-5-7-21-23(17-19)30-24-18-20(6-8-22(24)27(21)35)29-26(34)10-16-32-13-3-4-14-32/h5-8,17-18H,1-4,9-16H2,(H,28,33)(H,29,34)(H,30,35)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155668 (3-Morpholin-4-yl-N-[6-(3-morpholin-4-yl-propionyla...) Show SMILES Oc1c2ccc(NC(=O)CCN3CCOCC3)cc2nc2cc(NC(=O)CCN3CCOCC3)ccc12 Show InChI InChI=1S/C27H33N5O5/c33-25(5-7-31-9-13-36-14-10-31)28-19-1-3-21-23(17-19)30-24-18-20(2-4-22(24)27(21)35)29-26(34)6-8-32-11-15-37-16-12-32/h1-4,17-18H,5-16H2,(H,28,33)(H,29,34)(H,30,35)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155665 (3-(4-Ethyl-piperazin-1-yl)-N-{6-[3-(4-ethyl-pipera...) Show SMILES CCN1CCN(CCC(=O)Nc2ccc3c(O)c4ccc(NC(=O)CCN5CCN(CC)CC5)cc4nc3c2)CC1 Show InChI InChI=1S/C31H43N7O3/c1-3-35-13-17-37(18-14-35)11-9-29(39)32-23-5-7-25-27(21-23)34-28-22-24(6-8-26(28)31(25)41)33-30(40)10-12-38-19-15-36(4-2)16-20-38/h5-8,21-22H,3-4,9-20H2,1-2H3,(H,32,39)(H,33,40)(H,34,41)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155649 (CHEMBL1078516 | CHEMBL187202 | N-[9-Oxo-7-(3-pyrro...) Show SMILES Oc1c2cc(NC(=O)CCN3CCCC3)ccc2nc2ccc(NC(=O)CCN3CCCC3)cc12 Show InChI InChI=1S/C27H33N5O3/c33-25(9-15-31-11-1-2-12-31)28-19-5-7-23-21(17-19)27(35)22-18-20(6-8-24(22)30-23)29-26(34)10-16-32-13-3-4-14-32/h5-8,17-18H,1-4,9-16H2,(H,28,33)(H,29,34)(H,30,35)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50155655 (3-Diethylamino-N-[6-(3-diethylamino-propionylamino...) Show SMILES CCN(CC)CCC(=O)Nc1ccc2c(O)c3cc(NC(=O)CCN(CC)CC)ccc3nc2c1 Show InChI InChI=1S/C27H37N5O3/c1-5-31(6-2)15-13-25(33)28-19-10-12-23-22(17-19)27(35)21-11-9-20(18-24(21)30-23)29-26(34)14-16-32(7-3)8-4/h9-12,17-18H,5-8,13-16H2,1-4H3,(H,28,33)(H,29,34)(H,30,35)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	700	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of telomerase activity				Bioorg Med Chem Lett 14: 5845-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.037 BindingDB Entry DOI: 10.7270/Q26D5SG9
					More data for this Ligand-Target Pair