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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50018085   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 4


(Rattus norvegicus (Rat))
BDBM50191052
PNG
((2S,4S)-4-amino-1-((E)-3-carboxyacryloyl)pyrrolidi...)
Show SMILES N[C@]1(C[C@H](N(C1)C(=O)\C=C\C(O)=O)C(O)=O)C(O)=O
Show InChI InChI=1S/C10H12N2O7/c11-10(9(18)19)3-5(8(16)17)12(4-10)6(13)1-2-7(14)15/h1-2,5H,3-4,11H2,(H,14,15)(H,16,17)(H,18,19)/b2-1+/t5-,10-/m0/s1
PDB

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MCE
PC cid
PC sid
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Article
PubMed
n/an/an/an/a 4.83E+4n/an/an/an/a



Faust Pharmaceuticals

Curated by ChEMBL


Assay Description
Activity at rat mGluR4 receptor measured as intracellular calcium concentration in HEK293 cells


Bioorg Med Chem Lett 16: 4856-60 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.062
BindingDB Entry DOI: 10.7270/Q2833RNW
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Rattus norvegicus (Rat))
BDBM50060137
PNG
((1R,2S)-4-aminocyclopentane-1,2,4-tricarboxylic ac...)
Show SMILES N[C@]1(C[C@@H]([C@@H](C1)C(O)=O)C(O)=O)C(O)=O
Show InChI InChI=1S/C8H11NO6/c9-8(7(14)15)1-3(5(10)11)4(2-8)6(12)13/h3-4H,1-2,9H2,(H,10,11)(H,12,13)(H,14,15)/t3-,4+,8-
PDB

UniProtKB/SwissProt

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CHEMBL
MCE
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 7.20E+3n/an/an/an/a



Faust Pharmaceuticals

Curated by ChEMBL


Assay Description
Activity at rat mGluR4 receptor measured as intracellular calcium concentration in HEK293 cells


Bioorg Med Chem Lett 16: 4856-60 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.062
BindingDB Entry DOI: 10.7270/Q2833RNW
More data for this
Ligand-Target Pair