Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transient receptor potential cation channel subfamily V member 4 (Mus musculus) | BDBM50277489 (4alpha-Phorbol 12,13-dinonanoate | CHEMBL130626) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a |
KU Leuven Curated by ChEMBL | Assay Description Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentration | J Med Chem 52: 2933-9 (2009) Article DOI: 10.1021/jm9001007 BindingDB Entry DOI: 10.7270/Q27945K3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Mus musculus) | BDBM50277740 (4-Deoxy-4alpha-Phorbol 12,13-didecanoate | CHEMBL5...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a |
KU Leuven Curated by ChEMBL | Assay Description Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentration | J Med Chem 52: 2933-9 (2009) Article DOI: 10.1021/jm9001007 BindingDB Entry DOI: 10.7270/Q27945K3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Mus musculus) | BDBM50277487 (4alpha-Phorbol 12,13-dihexanoate | CHEMBL490470) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 70 | n/a | n/a | n/a | n/a |
KU Leuven Curated by ChEMBL | Assay Description Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentration | J Med Chem 52: 2933-9 (2009) Article DOI: 10.1021/jm9001007 BindingDB Entry DOI: 10.7270/Q27945K3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Mus musculus) | BDBM50277491 (CHEMBL504955 | Lumi-4alpha-Phorbol 12,13-didecanoa...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 175 | n/a | n/a | n/a | n/a |
KU Leuven Curated by ChEMBL | Assay Description Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentration | J Med Chem 52: 2933-9 (2009) Article DOI: 10.1021/jm9001007 BindingDB Entry DOI: 10.7270/Q27945K3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Mus musculus) | BDBM50277488 (4alpha-Phorbol 12,13-dioctanoate | CHEMBL507303) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a |
KU Leuven Curated by ChEMBL | Assay Description Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentration | J Med Chem 52: 2933-9 (2009) Article DOI: 10.1021/jm9001007 BindingDB Entry DOI: 10.7270/Q27945K3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Mus musculus) | BDBM50277486 (4alpha-Phorbol 13-decanoate | CHEMBL541720) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 450 | n/a | n/a | n/a | n/a |
KU Leuven Curated by ChEMBL | Assay Description Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentration | J Med Chem 52: 2933-9 (2009) Article DOI: 10.1021/jm9001007 BindingDB Entry DOI: 10.7270/Q27945K3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Mus musculus) | BDBM50277490 (4alpha-Phorbol 12,13-dimyristate | CHEMBL451849) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.83E+3 | n/a | n/a | n/a | n/a |
KU Leuven Curated by ChEMBL | Assay Description Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentration | J Med Chem 52: 2933-9 (2009) Article DOI: 10.1021/jm9001007 BindingDB Entry DOI: 10.7270/Q27945K3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Mus musculus) | BDBM50057512 ((1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b-dihydroxy-3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.25E+4 | n/a | n/a | n/a | n/a |
KU Leuven Curated by ChEMBL | Assay Description Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentration | J Med Chem 52: 2933-9 (2009) Article DOI: 10.1021/jm9001007 BindingDB Entry DOI: 10.7270/Q27945K3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Mus musculus) | BDBM50277739 (4alpha-phorbol diacetate | CHEMBL484343) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a |
KU Leuven Curated by ChEMBL | Assay Description Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentration | J Med Chem 52: 2933-9 (2009) Article DOI: 10.1021/jm9001007 BindingDB Entry DOI: 10.7270/Q27945K3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Mus musculus) | BDBM50240777 (4alpha-phorbol-didecanoate | CHEMBL118987 | Decano...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 370 | n/a | n/a | n/a | n/a |
KU Leuven Curated by ChEMBL | Assay Description Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentration | J Med Chem 52: 2933-9 (2009) Article DOI: 10.1021/jm9001007 BindingDB Entry DOI: 10.7270/Q27945K3 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |