Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM50001839 (CHEMBL428647 | PACLITAXEL | taxol) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.65E+4 | n/a | 4.20E+4 | n/a | n/a | n/a | n/a | 10.5 | n/a |
Ahi Evran University | Assay Description Paraoxonase enzyme activity was determined at 25 °C with paraoxon (1 mM) in 50 mM glycine-NaOH (pH 10.5) containing 1 mM CaCl2. The enzyme assay was ... | Chem Biol Drug Des 88: 188-96 (2016) Article DOI: 10.1111/cbdd.12746 BindingDB Entry DOI: 10.7270/Q2SB44JJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM50127140 ((-)-etoposide | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.31E+5 | n/a | 2.26E+5 | n/a | n/a | n/a | n/a | 10.5 | n/a |
Ahi Evran University | Assay Description Paraoxonase enzyme activity was determined at 25 °C with paraoxon (1 mM) in 50 mM glycine-NaOH (pH 10.5) containing 1 mM CaCl2. The enzyme assay was ... | Chem Biol Drug Des 88: 188-96 (2016) Article DOI: 10.1111/cbdd.12746 BindingDB Entry DOI: 10.7270/Q2SB44JJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM36351 (CID148124 | Docetaxel) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 2.91E+5 | n/a | 6.65E+5 | n/a | n/a | n/a | n/a | 10.5 | n/a |
Ahi Evran University | Assay Description Paraoxonase enzyme activity was determined at 25 °C with paraoxon (1 mM) in 50 mM glycine-NaOH (pH 10.5) containing 1 mM CaCl2. The enzyme assay was ... | Chem Biol Drug Des 88: 188-96 (2016) Article DOI: 10.1111/cbdd.12746 BindingDB Entry DOI: 10.7270/Q2SB44JJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM189358 (Asta Z 4942 | Ifosfamide | Iphosphamide | N,3-bis(...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid UniChem | Article PubMed | 8.97E+6 | n/a | 2.33E+7 | n/a | n/a | n/a | n/a | 10.5 | n/a |
Ahi Evran University | Assay Description Paraoxonase enzyme activity was determined at 25 °C with paraoxon (1 mM) in 50 mM glycine-NaOH (pH 10.5) containing 1 mM CaCl2. The enzyme assay was ... | Chem Biol Drug Des 88: 188-96 (2016) Article DOI: 10.1111/cbdd.12746 BindingDB Entry DOI: 10.7270/Q2SB44JJ | |||||||||||
More data for this Ligand-Target Pair |