Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase Fyn (Homo sapiens (Human)) | BDBM13216 (BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Silesia in Katowice Curated by ChEMBL | Assay Description Inhibition of Fyn A (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assay | Eur J Med Chem 163: 610-625 (2019) Article DOI: 10.1016/j.ejmech.2018.12.012 BindingDB Entry DOI: 10.7270/Q29P353V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Fyn (Homo sapiens (Human)) | BDBM13216 (BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Silesia in Katowice Curated by ChEMBL | Assay Description Inhibition of Fyn A (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assay | Eur J Med Chem 163: 610-625 (2019) Article DOI: 10.1016/j.ejmech.2018.12.012 BindingDB Entry DOI: 10.7270/Q29P353V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Fyn (Homo sapiens (Human)) | BDBM50529755 (CHEMBL4476482) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 191 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Silesia in Katowice Curated by ChEMBL | Assay Description Inhibition of Fyn A (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assay | Eur J Med Chem 163: 610-625 (2019) Article DOI: 10.1016/j.ejmech.2018.12.012 BindingDB Entry DOI: 10.7270/Q29P353V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Fyn (Homo sapiens (Human)) | BDBM50529755 (CHEMBL4476482) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 191 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Silesia in Katowice Curated by ChEMBL | Assay Description Inhibition of Fyn A (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assay | Eur J Med Chem 163: 610-625 (2019) Article DOI: 10.1016/j.ejmech.2018.12.012 BindingDB Entry DOI: 10.7270/Q29P353V | |||||||||||
More data for this Ligand-Target Pair |