BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with all data for assayid = 2 entry = 243
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM246889 (7-(1-(9H-purin-6- ylamino)ethyl)-6-(3- fluoropheny...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description In some embodiments, the PI3Kδ inhibitor is selective. By �selective� is meant that the compound binds to or inhibits a kinase with greater aff...				US Patent US10053465 (2018) BindingDB Entry DOI: 10.7270/Q2B27X98
Incyte Corporation US Patent					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50004547 (CHEMBL2216863 \| US10065963, Compound 28 \| US104280...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description In some embodiments, the PI3Kδ inhibitor is selective. By �selective� is meant that the compound binds to or inhibits a kinase with greater aff...				US Patent US10053465 (2018) BindingDB Entry DOI: 10.7270/Q2B27X98
Incyte Corporation US Patent					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM246891 (4-[1-(4-amino-3-methyl- 1H-pyrazolo[3,4- d]pyrimid...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description In some embodiments, the PI3Kδ inhibitor is selective. By �selective� is meant that the compound binds to or inhibits a kinase with greater aff...				US Patent US10053465 (2018) BindingDB Entry DOI: 10.7270/Q2B27X98
Incyte Corporation US Patent					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM246892 (4-[1-(4-amino-3-methyl- 1H-pyrazolo[3,4- d]pyrimid...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description In some embodiments, the PI3Kδ inhibitor is selective. By �selective� is meant that the compound binds to or inhibits a kinase with greater aff...				US Patent US10053465 (2018) BindingDB Entry DOI: 10.7270/Q2B27X98
Incyte Corporation US Patent					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM246893 (5-{3-[1-(4-amino-3- methyl-1H-pyrazolo[3,4 d]pyrim...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description In some embodiments, the PI3Kδ inhibitor is selective. By �selective� is meant that the compound binds to or inhibits a kinase with greater aff...				US Patent US10053465 (2018) BindingDB Entry DOI: 10.7270/Q2B27X98
Incyte Corporation US Patent					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM246897 (1-Methyl-N-({2-[3-(7H-pyrrolo[2,3-d]pyrimidin-4-yl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description In some embodiments, the PI3Kδ inhibitor is selective. By �selective� is meant that the compound binds to or inhibits a kinase with greater aff...				US Patent US10053465 (2018) BindingDB Entry DOI: 10.7270/Q2B27X98
Incyte Corporation US Patent					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50004539 (CHEMBL2216867 \| US10065963, Compound 33 \| US105191...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description In some embodiments, the PI3Kδ inhibitor is selective. By �selective� is meant that the compound binds to or inhibits a kinase with greater aff...				US Patent US10053465 (2018) BindingDB Entry DOI: 10.7270/Q2B27X98
Incyte Corporation US Patent					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM246896 (4-chloro-3'-fluoro-3- methyl-6-[1-(9H-purin-6-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description In some embodiments, the PI3Kδ inhibitor is selective. By �selective� is meant that the compound binds to or inhibits a kinase with greater aff...				US Patent US10053465 (2018) BindingDB Entry DOI: 10.7270/Q2B27X98
Incyte Corporation US Patent					More data for this Ligand-Target Pair