Compile Data Set for Download or QSAR

Found 37 hits Enz. Inhib. hit(s) with all data for assayid = 2 entry = 2630   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM266453 (US9718822, 1 | US9750744, Example 1 | US9902741, E...) Show SMILES Fc1cc2[C@H]3CCCN3c3ccn4ncc(C(=O)NCCCn(c1)c2=O)c4n3 |r| Show InChI InChI=1S/C19H19FN6O2/c20-12-9-13-15-3-1-7-25(15)16-4-8-26-17(23-16)14(10-22-26)18(27)21-5-2-6-24(11-12)19(13)28/h4,8-11,15H,1-3,5-7H2,(H,21,27)/t15-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267469 (US10688100, Compound 45 | US10966985, Compound 45 ...) Show SMILES O[C@H]1CNC(=O)c2cnn3ccc(nc23)N2CC(F)(F)CC2c2cc(F)ccc2OC1 |r| Show InChI InChI=1S/C20H18F3N5O3/c21-11-1-2-16-13(5-11)15-6-20(22,23)10-27(15)17-3-4-28-18(26-17)14(8-25-28)19(30)24-7-12(29)9-31-16/h1-5,8,12,15,29H,6-7,9-10H2,(H,24,30)/t12-,15?/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267416 (US10688100, Compound 9 | US10966985, Compound 9 | ...) Show SMILES Fc1cnc2OCCNC(=O)c3cnn4ccc(nc34)N3CCC[C@@H]3c2c1 |r| Show InChI InChI=1S/C18H17FN6O2/c19-11-8-12-14-2-1-5-24(14)15-3-6-25-16(23-15)13(10-22-25)17(26)20-4-7-27-18(12)21-9-11/h3,6,8-10,14H,1-2,4-5,7H2,(H,20,26)/t14-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267410 (US9718822, 4 | US9718822, 6 | US9750744, Example 6...) Show SMILES OC1CNC(=O)c2cnn3ccc(nc23)N2CCC[C@@H]2c2cc(F)cnc2OC1 |r| Show InChI InChI=1S/C19H19FN6O3/c20-11-6-13-15-2-1-4-25(15)16-3-5-26-17(24-16)14(9-23-26)18(28)21-8-12(27)10-29-19(13)22-7-11/h3,5-7,9,12,15,27H,1-2,4,8,10H2,(H,21,28)/t12?,15-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267411 (US9718822, 5 | US9750744, Example 5 | US9902741, E...) Show SMILES O[C@H]1CNC(=O)c2cnn3ccc(nc23)N2CCC[C@@H]2c2cc(F)cn(C1)c2=O |r| Show InChI InChI=1S/C19H19FN6O3/c20-11-6-13-15-2-1-4-25(15)16-3-5-26-17(23-16)14(8-22-26)18(28)21-7-12(27)10-24(9-11)19(13)29/h3,5-6,8-9,12,15,27H,1-2,4,7,10H2,(H,21,28)/t12-,15+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267410 (US9718822, 4 | US9718822, 6 | US9750744, Example 6...) Show SMILES OC1CNC(=O)c2cnn3ccc(nc23)N2CCC[C@@H]2c2cc(F)cnc2OC1 |r| Show InChI InChI=1S/C19H19FN6O3/c20-11-6-13-15-2-1-4-25(15)16-3-5-26-17(24-16)14(9-23-26)18(28)21-8-12(27)10-29-19(13)22-7-11/h3,5-7,9,12,15,27H,1-2,4,8,10H2,(H,21,28)/t12?,15-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267414 (US10688100, Compound 7 | US10966985, Compound 7 | ...) Show SMILES O[C@@H]1CNC(=O)c2cnn3ccc(nc23)N2CCC[C@@H]2c2cc(F)cnc2OC1 |r| Show InChI InChI=1S/C19H19FN6O3/c20-11-6-13-15-2-1-4-25(15)16-3-5-26-17(24-16)14(9-23-26)18(28)21-8-12(27)10-29-19(13)22-7-11/h3,5-7,9,12,15,27H,1-2,4,8,10H2,(H,21,28)/t12-,15-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267415 (US9718822, 8 | US9750744, Example 8 | US9902741, E...) Show SMILES O[C@@H]1CNC(=O)c2cnn3ccc(nc23)N2CCC[C@@H]2c2cc(F)cn(C1)c2=O |r| Show InChI InChI=1S/C19H19FN6O3/c20-11-6-13-15-2-1-4-25(15)16-3-5-26-17(23-16)14(8-22-26)18(28)21-7-12(27)10-24(9-11)19(13)29/h3,5-6,8-9,12,15,27H,1-2,4,7,10H2,(H,21,28)/t12-,15-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267416 (US10688100, Compound 9 | US10966985, Compound 9 | ...) Show SMILES Fc1cnc2OCCNC(=O)c3cnn4ccc(nc34)N3CCC[C@@H]3c2c1 |r| Show InChI InChI=1S/C18H17FN6O2/c19-11-8-12-14-2-1-5-24(14)15-3-6-25-16(23-15)13(10-22-25)17(26)20-4-7-27-18(12)21-9-11/h3,6,8-10,14H,1-2,4-5,7H2,(H,20,26)/t14-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267416 (US10688100, Compound 9 | US10966985, Compound 9 | ...) Show SMILES Fc1cnc2OCCNC(=O)c3cnn4ccc(nc34)N3CCC[C@@H]3c2c1 |r| Show InChI InChI=1S/C18H17FN6O2/c19-11-8-12-14-2-1-5-24(14)15-3-6-25-16(23-15)13(10-22-25)17(26)20-4-7-27-18(12)21-9-11/h3,6,8-10,14H,1-2,4-5,7H2,(H,20,26)/t14-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267419 (US9718822, 11 | US9902741, Example 11) Show SMILES Fc1cc2[C@H]3CCCN3c3ccn4ncc(C(=O)NCCCCn(c1)c2=O)c4n3 |r| Show InChI InChI=1S/C20H21FN6O2/c21-13-10-14-16-4-3-8-26(16)17-5-9-27-18(24-17)15(11-23-27)19(28)22-6-1-2-7-25(12-13)20(14)29/h5,9-12,16H,1-4,6-8H2,(H,22,28)/t16-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267429 (US9718822, 16 | US9750744, Example 16 | US9902741,...) Show SMILES Fc1cnc2OCCONC(=O)c3cnn4ccc(nc34)N3CCC[C@@H]3c2c1 |r| Show InChI InChI=1S/C18H17FN6O3/c19-11-8-12-14-2-1-4-24(14)15-3-5-25-16(22-15)13(10-21-25)17(26)23-28-7-6-27-18(12)20-9-11/h3,5,8-10,14H,1-2,4,6-7H2,(H,23,26)/t14-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267431 (US9718822, 18 | US9750744, Example 18 | US9902741,...) Show SMILES CN1CCCOc2ncc(F)cc2[C@H]2CCCN2c2ccn3ncc(C1=O)c3n2 |r| Show InChI InChI=1S/C20H21FN6O2/c1-25-6-3-9-29-19-14(10-13(21)11-22-19)16-4-2-7-26(16)17-5-8-27-18(24-17)15(12-23-27)20(25)28/h5,8,10-12,16H,2-4,6-7,9H2,1H3/t16-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267434 (US10688100, Compound 19 | US10966985, Compound 19 ...) Show SMILES Fc1cnc2OCC(F)(F)CNC(=O)c3cnn4ccc(nc34)N3CCC[C@@H]3c2c1 |r| Show InChI InChI=1S/C19H17F3N6O2/c20-11-6-12-14-2-1-4-27(14)15-3-5-28-16(26-15)13(8-25-28)17(29)24-9-19(21,22)10-30-18(12)23-7-11/h3,5-8,14H,1-2,4,9-10H2,(H,24,29)/t14-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267436 (US10688100, Compound 20 | US10966985, Compound 20 ...) Show SMILES Fc1ccc2OCCCNC(=O)c3cnn4ccc(nc34)N3CCC[C@@H]3c2c1 |r| Show InChI InChI=1S/C20H20FN5O2/c21-13-4-5-17-14(11-13)16-3-1-8-25(16)18-6-9-26-19(24-18)15(12-23-26)20(27)22-7-2-10-28-17/h4-6,9,11-12,16H,1-3,7-8,10H2,(H,22,27)/t16-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267440 (US9718822, 23 | US9750744, Example 23 | US9902741,...) Show SMILES OCC(=O)N1CCOc2ccc(F)cc2[C@H]2CCCN2c2ccn3ncc(C1)c3n2 |r| Show InChI InChI=1S/C21H22FN5O3/c22-15-3-4-18-16(10-15)17-2-1-6-26(17)19-5-7-27-21(24-19)14(11-23-27)12-25(8-9-30-18)20(29)13-28/h3-5,7,10-11,17,28H,1-2,6,8-9,12-13H2/t17-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM266501 (US10688100, Compound 2 | US10966985, Compound 2 | ...) Show SMILES O=C1NCCCOc2cccc(n2)[C@H]2CCCN2c2ccn3ncc1c3n2 |r| Show InChI InChI=1S/C19H20N6O2/c26-19-13-12-21-25-10-7-16(23-18(13)25)24-9-2-5-15(24)14-4-1-6-17(22-14)27-11-3-8-20-19/h1,4,6-7,10,12,15H,2-3,5,8-9,11H2,(H,20,26)/t15-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267469 (US10688100, Compound 45 | US10966985, Compound 45 ...) Show SMILES O[C@H]1CNC(=O)c2cnn3ccc(nc23)N2CC(F)(F)CC2c2cc(F)ccc2OC1 |r| Show InChI InChI=1S/C20H18F3N5O3/c21-11-1-2-16-13(5-11)15-6-20(22,23)10-27(15)17-3-4-28-18(26-17)14(8-25-28)19(30)24-7-12(29)9-31-16/h1-5,8,12,15,29H,6-7,9-10H2,(H,24,30)/t12-,15?/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267468 (US9718822, 44-B | US9750744, Example 44-B | US9902...) Show SMILES O[C@@H]1C[C@@H]2N(C1)c1ccn3ncc(C(=O)NC[C@@H](O)COc4ccc(F)cc24)c3n1 |r| Show InChI InChI=1S/C20H20FN5O4/c21-11-1-2-17-14(5-11)16-6-12(27)9-25(16)18-3-4-26-19(24-18)15(8-23-26)20(29)22-7-13(28)10-30-17/h1-5,8,12-13,16,27-28H,6-7,9-10H2,(H,22,29)/t12-,13-,16+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267467 (US9718822, 44 | US9750744, Example 44 | US9902741,...) Show SMILES O[C@@H]1C[C@H]2N(C1)c1ccn3ncc(C(=O)NC[C@@H](O)COc4ccc(F)cc24)c3n1 |r| Show InChI InChI=1S/C20H20FN5O4/c21-11-1-2-17-14(5-11)16-6-12(27)9-25(16)18-3-4-26-19(24-18)15(8-23-26)20(29)22-7-13(28)10-30-17/h1-5,8,12-13,16,27-28H,6-7,9-10H2,(H,22,29)/t12-,13-,16-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267465 (US9718822, 43 | US9750744, Example 43 | US9902741,...) Show SMILES O[C@@H]1C[C@H]2N(C1)c1ccn3ncc(C(=O)NCCOc4ccc(F)cc24)c3n1 |r| Show InChI InChI=1S/C19H18FN5O3/c20-11-1-2-16-13(7-11)15-8-12(26)10-24(15)17-3-5-25-18(23-17)14(9-22-25)19(27)21-4-6-28-16/h1-3,5,7,9,12,15,26H,4,6,8,10H2,(H,21,27)/t12-,15-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267449 (US9718822, 32 | US9750744, Example 32 | US9902741,...) Show SMILES Fc1cnc2CCCNC(=O)c3cnn4ccc(nc34)N3CCC[C@@H]3c2c1 |r| Show InChI InChI=1S/C19H19FN6O/c20-12-9-13-15(22-10-12)3-1-6-21-19(27)14-11-23-26-8-5-17(24-18(14)26)25-7-2-4-16(13)25/h5,8-11,16H,1-4,6-7H2,(H,21,27)/t16-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267450 (US9718822, 33 | US9750744, Example 33 | US9902741,...) Show SMILES CC1CCc2ncc(F)cc2[C@H]2CCCN2c2ccn3ncc(C(=O)N1)c3n2 |r| Show InChI InChI=1S/C20H21FN6O/c1-12-4-5-16-14(9-13(21)10-22-16)17-3-2-7-26(17)18-6-8-27-19(25-18)15(11-23-27)20(28)24-12/h6,8-12,17H,2-5,7H2,1H3,(H,24,28)/t12?,17-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267451 (BDBM337663 | US9718822, 34 | US9902741, Example 34) Show SMILES C[C@@H]1CNC(=O)c2cnn3ccc(nc23)N2CCC[C@@H]2c2cc(F)cn(C1)c2=O |r| Show InChI InChI=1S/C20H21FN6O2/c1-12-8-22-19(28)15-9-23-27-6-4-17(24-18(15)27)26-5-2-3-16(26)14-7-13(21)11-25(10-12)20(14)29/h4,6-7,9,11-12,16H,2-3,5,8,10H2,1H3,(H,22,28)/t12-,16-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267452 (US10688100, Compound 35 | US10966985, Compound 35 ...) Show SMILES C[C@H]1CNC(=O)c2cnn3ccc(nc23)N2CCC[C@@H]2c2cc(F)cn(C1)c2=O |r| Show InChI InChI=1S/C20H21FN6O2/c1-12-8-22-19(28)15-9-23-27-6-4-17(24-18(15)27)26-5-2-3-16(26)14-7-13(21)11-25(10-12)20(14)29/h4,6-7,9,11-12,16H,2-3,5,8,10H2,1H3,(H,22,28)/t12-,16+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267453 (US10688100, Compound 36 | US10966985, Compound 36 ...) Show SMILES CC1(C)CNC(=O)c2cnn3ccc(nc23)N2CCC[C@@H]2c2cc(F)cnc2OC1 |r| Show InChI InChI=1S/C21H23FN6O2/c1-21(2)11-24-19(29)15-10-25-28-7-5-17(26-18(15)28)27-6-3-4-16(27)14-8-13(22)9-23-20(14)30-12-21/h5,7-10,16H,3-4,6,11-12H2,1-2H3,(H,24,29)/t16-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267454 (US9718822, 37 | US9750744, Example 37 | US9902741,...) Show SMILES CC1(C)CCc2ncc(F)cc2[C@H]2CCCN2c2ccn3ncc(C(=O)N1)c3n2 |r| Show InChI InChI=1S/C21H23FN6O/c1-21(2)7-5-16-14(10-13(22)11-23-16)17-4-3-8-27(17)18-6-9-28-19(25-18)15(12-24-28)20(29)26-21/h6,9-12,17H,3-5,7-8H2,1-2H3,(H,26,29)/t17-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267457 (US9718822, 38 | US9750744, Example 38 | US9902741,...) Show SMILES Fc1cnc2OCCn3nccc3NC(=O)c3cnn4ccc(nc34)N3CCC[C@@H]3c2c1 |r| Show InChI InChI=1S/C21H19FN8O2/c22-13-10-14-16-2-1-6-28(16)17-4-7-30-19(26-17)15(12-25-30)20(31)27-18-3-5-24-29(18)8-9-32-21(14)23-11-13/h3-5,7,10-12,16H,1-2,6,8-9H2,(H,27,31)/t16-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267458 (US9718822, 39 | US9750744, Example 39 | US9902741,...) Show SMILES Fc1cnc2OCc3cccnc3NC(=O)c3cnn4ccc(nc34)N3CCC[C@@H]3c2c1 |r| Show InChI InChI=1S/C22H18FN7O2/c23-14-9-15-17-4-2-7-29(17)18-5-8-30-20(27-18)16(11-26-30)21(31)28-19-13(3-1-6-24-19)12-32-22(15)25-10-14/h1,3,5-6,8-11,17H,2,4,7,12H2,(H,24,28,31)/t17-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267460 (US9718822, 40 | US9750744, Example 40 | US9902741,...) Show SMILES CC1(C)CNC(=O)c2cnn3ccc(nc23)N2CCC[C@@H]2c2cc(F)cn(C1)c2=O |r| Show InChI InChI=1S/C21H23FN6O2/c1-21(2)11-23-19(29)15-9-24-28-7-5-17(25-18(15)28)27-6-3-4-16(27)14-8-13(22)10-26(12-21)20(14)30/h5,7-10,16H,3-4,6,11-12H2,1-2H3,(H,23,29)/t16-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267461 (US9718822, 41 | US9750744, Example 41 | US9902741,...) Show SMILES O[C@@H]1C[C@H]2N(C1)c1ccn3ncc(C(=O)NC[C@H](O)COc4ccc(F)cc24)c3n1 |r| Show InChI InChI=1S/C20H20FN5O4/c21-11-1-2-17-14(5-11)16-6-12(27)9-25(16)18-3-4-26-19(24-18)15(8-23-26)20(29)22-7-13(28)10-30-17/h1-5,8,12-13,16,27-28H,6-7,9-10H2,(H,22,29)/t12-,13+,16-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267463 (US9718822, 42 | US9750744, Example 42 | US9902741,...) Show SMILES O[C@@H]1C[C@H]2N(C1)c1ccn3ncc(C(=O)NCCCOc4ccc(F)cc24)c3n1 |r| Show InChI InChI=1S/C20H20FN5O3/c21-12-2-3-17-14(8-12)16-9-13(27)11-25(16)18-4-6-26-19(24-18)15(10-23-26)20(28)22-5-1-7-29-17/h2-4,6,8,10,13,16,27H,1,5,7,9,11H2,(H,22,28)/t13-,16-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267464 (US9718822, 42-B | US9750744, Example 42-B | US9902...) Show SMILES O[C@@H]1C[C@@H]2N(C1)c1ccn3ncc(C(=O)NCCCOc4ccc(F)cc24)c3n1 |r| Show InChI InChI=1S/C20H20FN5O3/c21-12-2-3-17-14(8-12)16-9-13(27)11-25(16)18-4-6-26-19(24-18)15(10-23-26)20(28)22-5-1-7-29-17/h2-4,6,8,10,13,16,27H,1,5,7,9,11H2,(H,22,28)/t13-,16+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267466 (US9718822, 43-B | US9750744, Example 43-B | US9902...) Show SMILES O[C@@H]1C[C@@H]2N(C1)c1ccn3ncc(C(=O)NCCOc4ccc(F)cc24)c3n1 |r| Show InChI InChI=1S/C19H18FN5O3/c20-11-1-2-16-13(7-11)15-8-12(26)10-24(15)17-3-5-25-18(23-17)14(9-22-25)19(27)21-4-6-28-16/h1-3,5,7,9,12,15,26H,4,6,8,10H2,(H,21,27)/t12-,15+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267462 (US9718822, 41-B | US9750744, Example 41-B | US9902...) Show SMILES O[C@@H]1C[C@@H]2N(C1)c1ccn3ncc(C(=O)NC[C@H](O)COc4ccc(F)cc24)c3n1 |r| Show InChI InChI=1S/C20H20FN5O4/c21-11-1-2-17-14(5-11)16-6-12(27)9-25(16)18-3-4-26-19(24-18)15(8-23-26)20(29)22-7-13(28)10-30-17/h1-5,8,12-13,16,27-28H,6-7,9-10H2,(H,22,29)/t12-,13+,16+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267448 (US9718822, 31 | US9750744, Example 31 | US9902741,...) Show SMILES Fc1cnc2OCCNC(=O)c3cnn4ccc(nc34)N3[C@H](COC3=O)c2c1 |r| Show InChI InChI=1S/C17H13FN6O4/c18-9-5-10-12-8-28-17(26)24(12)13-1-3-23-14(22-13)11(7-21-23)15(25)19-2-4-27-16(10)20-6-9/h1,3,5-7,12H,2,4,8H2,(H,19,25)/t12-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267443 (US9718822, 26 | US9750744, Example 26 | US9902741,...) Show SMILES OC(=O)CN1CCOc2ccc(F)cc2[C@H]2CCCN2c2ccn3ncc(C1)c3n2 |r| Show InChI InChI=1S/C21H22FN5O3/c22-15-3-4-18-16(10-15)17-2-1-6-26(17)19-5-7-27-21(24-19)14(11-23-27)12-25(8-9-30-18)13-20(28)29/h3-5,7,10-11,17H,1-2,6,8-9,12-13H2,(H,28,29)/t17-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair