BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with all data for assayid = 2 entry = 50007848
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50318884 (CHEMBL1084546 \| CHEMBL2430359 \| N-methyl-N-(3-((2-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant FAK (410 to 689 residues) (unknown origin) using Poly (4:1 Glu, Tyr) peptide as substrate enzyme pretreated with substrate ...				Eur J Med Chem 177: 32-46 (2019) Article DOI: 10.1016/j.ejmech.2019.05.048 BindingDB Entry DOI: 10.7270/Q2XS5ZQT
Peking University Health Science Center Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50269948 (6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Health Science Center Curated by ChEMBL					Assay Description Inhibition of recombinant FAK (410 to 689 residues) (unknown origin) using Poly (4:1 Glu, Tyr) peptide as substrate enzyme pretreated with substrate ...				Eur J Med Chem 177: 32-46 (2019) Article DOI: 10.1016/j.ejmech.2019.05.048 BindingDB Entry DOI: 10.7270/Q2XS5ZQT
Peking University Health Science Center Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)