Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Target of rapamycin complex subunit LST8 (Homo sapiens) | BDBM50546183![]() (CHEMBL4744705) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of mTORC1 in human A2058 cells assessed as reduction in ribosomal protein S6 phosphorylation at Ser235/236 residues incubated for 1 hr by ... | Citation and Details Article DOI: 10.1021/acsmedchemlett.9b00333 BindingDB Entry DOI: 10.7270/Q2VT1WPR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Target of rapamycin complex subunit LST8 (Homo sapiens) | BDBM50546185![]() (CHEMBL4749136) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 91 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of mTORC1 in human A2058 cells assessed as reduction in ribosomal protein S6 phosphorylation at Ser235/236 residues incubated for 1 hr by ... | Citation and Details Article DOI: 10.1021/acsmedchemlett.9b00333 BindingDB Entry DOI: 10.7270/Q2VT1WPR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Target of rapamycin complex subunit LST8 (Homo sapiens) | BDBM50546184![]() (CHEMBL4758284) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 116 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of mTORC1 in human A2058 cells assessed as reduction in ribosomal protein S6 phosphorylation at Ser235/236 residues incubated for 1 hr by ... | Citation and Details Article DOI: 10.1021/acsmedchemlett.9b00333 BindingDB Entry DOI: 10.7270/Q2VT1WPR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Target of rapamycin complex subunit LST8 (Homo sapiens) | BDBM50546186![]() (CHEMBL4754767) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 139 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of mTORC1 in human A2058 cells assessed as reduction in ribosomal protein S6 phosphorylation at Ser235/236 residues incubated for 1 hr by ... | Citation and Details Article DOI: 10.1021/acsmedchemlett.9b00333 BindingDB Entry DOI: 10.7270/Q2VT1WPR | |||||||||||
More data for this Ligand-Target Pair |