Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human)) | BDBM25017![]() (2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of RSK2 in human MOLM-13 assessed as reduction in cell viability measured after 72 hrs by MTS assay | Citation and Details Article DOI: 10.1016/j.bmc.2021.116220 BindingDB Entry DOI: 10.7270/Q2H70KKB | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human)) | BDBM50568104![]() (CHEMBL4858257 | US11851436, Compound A1-2) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 970 | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of RSK2 in human MOLM-13 assessed as reduction in cell viability measured after 72 hrs by MTS assay | Citation and Details Article DOI: 10.1016/j.bmc.2021.116220 BindingDB Entry DOI: 10.7270/Q2H70KKB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human)) | BDBM50568106![]() (CHEMBL4849660 | US11851436, Compound A1-4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of RSK2 in human MOLM-13 assessed as reduction in cell viability measured after 72 hrs by MTS assay | Citation and Details Article DOI: 10.1016/j.bmc.2021.116220 BindingDB Entry DOI: 10.7270/Q2H70KKB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human)) | BDBM50568115![]() (CHEMBL4864190) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 70 | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of RSK2 in human MOLM-13 assessed as reduction in cell viability measured after 72 hrs by MTS assay | Citation and Details Article DOI: 10.1016/j.bmc.2021.116220 BindingDB Entry DOI: 10.7270/Q2H70KKB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human)) | BDBM50568113![]() (CHEMBL4873445) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of RSK2 in human MOLM-13 assessed as reduction in cell viability measured after 72 hrs by MTS assay | Citation and Details Article DOI: 10.1016/j.bmc.2021.116220 BindingDB Entry DOI: 10.7270/Q2H70KKB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human)) | BDBM50568114![]() (CHEMBL4857399) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 230 | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of RSK2 in human MOLM-13 assessed as reduction in cell viability measured after 72 hrs by MTS assay | Citation and Details Article DOI: 10.1016/j.bmc.2021.116220 BindingDB Entry DOI: 10.7270/Q2H70KKB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human)) | BDBM50568112![]() (CHEMBL4851452) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.39E+4 | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of RSK2 in human MOLM-13 assessed as reduction in cell viability measured after 72 hrs by MTS assay | Citation and Details Article DOI: 10.1016/j.bmc.2021.116220 BindingDB Entry DOI: 10.7270/Q2H70KKB | |||||||||||
More data for this Ligand-Target Pair |