Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 3 (Homo sapiens (Human)) | BDBM50134435 (CHEMBL3747735) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 74 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Antagonist activity at human mGlu3 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 3 (Homo sapiens (Human)) | BDBM50134438 (CHEMBL3747073) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 150 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Antagonist activity at human mGlu3 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 3 (Homo sapiens (Human)) | BDBM50134443 (CHEMBL3746457) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.76E+3 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Antagonist activity at human mGlu3 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 3 (Homo sapiens (Human)) | BDBM50134469 (CHEMBL3746344) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 540 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Antagonist activity at human mGlu3 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 3 (Homo sapiens (Human)) | BDBM50134455 (CHEMBL3747522) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 290 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Antagonist activity at human mGlu3 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 3 (Homo sapiens (Human)) | BDBM50134466 (CHEMBL3747116) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.39E+3 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Antagonist activity at human mGlu3 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 3 (Homo sapiens (Human)) | BDBM50134449 (CHEMBL3745812) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 34 | n/a | n/a | n/a | n/a |
Janssen Research and Development Curated by ChEMBL | Assay Description Antagonist activity at human mGlu3 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization | Bioorg Med Chem Lett 26: 429-34 (2016) Article DOI: 10.1016/j.bmcl.2015.11.098 BindingDB Entry DOI: 10.7270/Q2SJ1NGS | |||||||||||
More data for this Ligand-Target Pair |