Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mineralocorticoid receptor [729-984] (Homo sapiens (Human)) | BDBM238163![]() (US10017502, Example 6 | US9394291, 6 | US9394291, ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 58 | n/a | n/a | n/a | n/a | 7.5 | n/a |
AstraZeneca AB US Patent | Assay Description Test A2: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at... | US Patent US9394291 (2016) BindingDB Entry DOI: 10.7270/Q2125RJS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mineralocorticoid receptor [729-984] (Homo sapiens (Human)) | BDBM238159![]() (US10017502, Example 4b | US9394291, 4a) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | 240 | n/a | n/a | n/a | n/a | 7.5 | n/a |
AstraZeneca AB US Patent | Assay Description Test A2: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at... | US Patent US9394291 (2016) BindingDB Entry DOI: 10.7270/Q2125RJS | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Mineralocorticoid receptor [729-984] (Homo sapiens (Human)) | BDBM238158![]() (US10017502, Example 4 | US9394291, 4) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | 740 | n/a | n/a | n/a | n/a | 7.5 | n/a |
AstraZeneca AB US Patent | Assay Description Test A2: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at... | US Patent US9394291 (2016) BindingDB Entry DOI: 10.7270/Q2125RJS | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Mineralocorticoid receptor [729-984] (Homo sapiens (Human)) | BDBM238152![]() (US10017502, Example 2 | US9394291, 2 | US9394291, ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
AstraZeneca AB US Patent | Assay Description Test A2: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at... | US Patent US9394291 (2016) BindingDB Entry DOI: 10.7270/Q2125RJS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mineralocorticoid receptor [729-984] (Homo sapiens (Human)) | BDBM238151![]() (US10017502, Example 1 | US9394291, 1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
AstraZeneca AB US Patent | Assay Description Test A2: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at... | US Patent US9394291 (2016) BindingDB Entry DOI: 10.7270/Q2125RJS | |||||||||||
More data for this Ligand-Target Pair |