Compile Data Set for Download or QSAR

Found 32 hits Enz. Inhib. hit(s) with all data for assayid = 3 entry = 50004522   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483684 (CHEMBL1766213) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)cc12)C(=O)NCN1CCCCC1 Show InChI InChI=1S/C23H26ClN3O3S/c1-15-10-16(2)12-18(11-15)31(29,30)22-19-13-17(24)6-7-20(19)26-21(22)23(28)25-14-27-8-4-3-5-9-27/h6-7,10-13,26H,3-5,8-9,14H2,1-2H3,(H,25,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483689 (CHEMBL1766210) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Br)cc12)C(=O)NCN1CCCC1 Show InChI InChI=1S/C22H24BrN3O3S/c1-14-9-15(2)11-17(10-14)30(28,29)21-18-12-16(23)5-6-19(18)25-20(21)22(27)24-13-26-7-3-4-8-26/h5-6,9-12,25H,3-4,7-8,13H2,1-2H3,(H,24,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483681 (CHEMBL1766209) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)cc12)C(=O)NCN1CCCC1 Show InChI InChI=1S/C22H24ClN3O3S/c1-14-9-15(2)11-17(10-14)30(28,29)21-18-12-16(23)5-6-19(18)25-20(21)22(27)24-13-26-7-3-4-8-26/h5-6,9-12,25H,3-4,7-8,13H2,1-2H3,(H,24,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483698 (CHEMBL1766215) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(cc12)[N+]([O-])=O)C(=O)NCN1CCCCC1 Show InChI InChI=1S/C23H26N4O5S/c1-15-10-16(2)12-18(11-15)33(31,32)22-19-13-17(27(29)30)6-7-20(19)25-21(22)23(28)24-14-26-8-4-3-5-9-26/h6-7,10-13,25H,3-5,8-9,14H2,1-2H3,(H,24,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483683 (CHEMBL1766237) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)cc12)C(=O)NCCn1cccc1 Show InChI InChI=1S/C23H22ClN3O3S/c1-15-11-16(2)13-18(12-15)31(29,30)22-19-14-17(24)5-6-20(19)26-21(22)23(28)25-7-10-27-8-3-4-9-27/h3-6,8-9,11-14,26H,7,10H2,1-2H3,(H,25,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483705 (CHEMBL1766223) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(cc12)[N+]([O-])=O)C(=O)NCc1ccccc1 Show InChI InChI=1S/C24H21N3O5S/c1-15-10-16(2)12-19(11-15)33(31,32)23-20-13-18(27(29)30)8-9-21(20)26-22(23)24(28)25-14-17-6-4-3-5-7-17/h3-13,26H,14H2,1-2H3,(H,25,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483682 (CHEMBL1766240) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)c(F)c12)C(=O)NCCn1cccc1 Show InChI InChI=1S/C23H21ClFN3O3S/c1-14-11-15(2)13-16(12-14)32(30,31)22-19-18(6-5-17(24)20(19)25)27-21(22)23(29)26-7-10-28-8-3-4-9-28/h3-6,8-9,11-13,27H,7,10H2,1-2H3,(H,26,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50033883 (CHEMBL1766221) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)cc12)C(=O)NCc1ccccc1 Show InChI InChI=1S/C24H21ClN2O3S/c1-15-10-16(2)12-19(11-15)31(29,30)23-20-13-18(25)8-9-21(20)27-22(23)24(28)26-14-17-6-4-3-5-7-17/h3-13,27H,14H2,1-2H3,(H,26,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483679 (CHEMBL1766214) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Br)cc12)C(=O)NCN1CCCCC1 Show InChI InChI=1S/C23H26BrN3O3S/c1-15-10-16(2)12-18(11-15)31(29,30)22-19-13-17(24)6-7-20(19)26-21(22)23(28)25-14-27-8-4-3-5-9-27/h6-7,10-13,26H,3-5,8-9,14H2,1-2H3,(H,25,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483707 (CHEMBL1766211) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(cc12)[N+]([O-])=O)C(=O)NCN1CCCC1 Show InChI InChI=1S/C22H24N4O5S/c1-14-9-15(2)11-17(10-14)32(30,31)21-18-12-16(26(28)29)5-6-19(18)24-20(21)22(27)23-13-25-7-3-4-8-25/h5-6,9-12,24H,3-4,7-8,13H2,1-2H3,(H,23,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483680 (CHEMBL1766239) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(cc12)[N+]([O-])=O)C(=O)NCCn1cccc1 Show InChI InChI=1S/C23H22N4O5S/c1-15-11-16(2)13-18(12-15)33(31,32)22-19-14-17(27(29)30)5-6-20(19)25-21(22)23(28)24-7-10-26-8-3-4-9-26/h3-6,8-9,11-14,25H,7,10H2,1-2H3,(H,24,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483685 (CHEMBL1766224) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)c(F)c12)C(=O)NCc1ccccc1 Show InChI InChI=1S/C24H20ClFN2O3S/c1-14-10-15(2)12-17(11-14)32(30,31)23-20-19(9-8-18(25)21(20)26)28-22(23)24(29)27-13-16-6-4-3-5-7-16/h3-12,28H,13H2,1-2H3,(H,27,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483706 (CHEMBL1766217) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)cc12)C(=O)NCN1CCOCC1 Show InChI InChI=1S/C22H24ClN3O4S/c1-14-9-15(2)11-17(10-14)31(28,29)21-18-12-16(23)3-4-19(18)25-20(21)22(27)24-13-26-5-7-30-8-6-26/h3-4,9-12,25H,5-8,13H2,1-2H3,(H,24,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483687 (CHEMBL1766231) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(cc12)[N+]([O-])=O)C(=O)NCCN1CCOCC1 Show InChI InChI=1S/C23H26N4O6S/c1-15-11-16(2)13-18(12-15)34(31,32)22-19-14-17(27(29)30)3-4-20(19)25-21(22)23(28)24-5-6-26-7-9-33-10-8-26/h3-4,11-14,25H,5-10H2,1-2H3,(H,24,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483686 (CHEMBL1766235) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(cc12)[N+]([O-])=O)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C25H23N3O5S/c1-16-12-17(2)14-20(13-16)34(32,33)24-21-15-19(28(30)31)8-9-22(21)27-23(24)25(29)26-11-10-18-6-4-3-5-7-18/h3-9,12-15,27H,10-11H2,1-2H3,(H,26,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483694 (CHEMBL1766230) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Br)cc12)C(=O)NCCN1CCOCC1 Show InChI InChI=1S/C23H26BrN3O4S/c1-15-11-16(2)13-18(12-15)32(29,30)22-19-14-17(24)3-4-20(19)26-21(22)23(28)25-5-6-27-7-9-31-10-8-27/h3-4,11-14,26H,5-10H2,1-2H3,(H,25,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483699 (CHEMBL1766226) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Br)cc12)C(=O)NCCN1CCCC1 Show InChI InChI=1S/C23H26BrN3O3S/c1-15-11-16(2)13-18(12-15)31(29,30)22-19-14-17(24)5-6-20(19)26-21(22)23(28)25-7-10-27-8-3-4-9-27/h5-6,11-14,26H,3-4,7-10H2,1-2H3,(H,25,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483688 (CHEMBL1766321) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)c(F)c12)C(=O)NCCOc1ccccc1 Show InChI InChI=1S/C25H22ClFN2O4S/c1-15-12-16(2)14-18(13-15)34(31,32)24-21-20(9-8-19(26)22(21)27)29-23(24)25(30)28-10-11-33-17-6-4-3-5-7-17/h3-9,12-14,29H,10-11H2,1-2H3,(H,28,30)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50033884 (CHEMBL1766233) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)cc12)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C25H23ClN2O3S/c1-16-12-17(2)14-20(13-16)32(30,31)24-21-15-19(26)8-9-22(21)28-23(24)25(29)27-11-10-18-6-4-3-5-7-18/h3-9,12-15,28H,10-11H2,1-2H3,(H,27,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483690 (CHEMBL1766220) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)c(F)c12)C(=O)NCN1CCOCC1 Show InChI InChI=1S/C22H23ClFN3O4S/c1-13-9-14(2)11-15(10-13)32(29,30)21-18-17(4-3-16(23)19(18)24)26-20(21)22(28)25-12-27-5-7-31-8-6-27/h3-4,9-11,26H,5-8,12H2,1-2H3,(H,25,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483691 (CHEMBL1766225) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)cc12)C(=O)NCCN1CCCC1 Show InChI InChI=1S/C23H26ClN3O3S/c1-15-11-16(2)13-18(12-15)31(29,30)22-19-14-17(24)5-6-20(19)26-21(22)23(28)25-7-10-27-8-3-4-9-27/h5-6,11-14,26H,3-4,7-10H2,1-2H3,(H,25,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483692 (CHEMBL1766229) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)cc12)C(=O)NCCN1CCOCC1 Show InChI InChI=1S/C23H26ClN3O4S/c1-15-11-16(2)13-18(12-15)32(29,30)22-19-14-17(24)3-4-20(19)26-21(22)23(28)25-5-6-27-7-9-31-10-8-27/h3-4,11-14,26H,5-10H2,1-2H3,(H,25,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483695 (CHEMBL1766234) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Br)cc12)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C25H23BrN2O3S/c1-16-12-17(2)14-20(13-16)32(30,31)24-21-15-19(26)8-9-22(21)28-23(24)25(29)27-11-10-18-6-4-3-5-7-18/h3-9,12-15,28H,10-11H2,1-2H3,(H,27,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	128	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483693 (CHEMBL1766219) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(cc12)[N+]([O-])=O)C(=O)NCN1CCOCC1 Show InChI InChI=1S/C22H24N4O6S/c1-14-9-15(2)11-17(10-14)33(30,31)21-18-12-16(26(28)29)3-4-19(18)24-20(21)22(27)23-13-25-5-7-32-8-6-25/h3-4,9-12,24H,5-8,13H2,1-2H3,(H,23,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483702 (CHEMBL1766228) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)c(F)c12)C(=O)NCCN1CCCC1 Show InChI InChI=1S/C23H25ClFN3O3S/c1-14-11-15(2)13-16(12-14)32(30,31)22-19-18(6-5-17(24)20(19)25)27-21(22)23(29)26-7-10-28-8-3-4-9-28/h5-6,11-13,27H,3-4,7-10H2,1-2H3,(H,26,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483696 (CHEMBL1766218) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Br)cc12)C(=O)NCN1CCOCC1 Show InChI InChI=1S/C22H24BrN3O4S/c1-14-9-15(2)11-17(10-14)31(28,29)21-18-12-16(23)3-4-19(18)25-20(21)22(27)24-13-26-5-7-30-8-6-26/h3-4,9-12,25H,5-8,13H2,1-2H3,(H,24,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	168	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483697 (CHEMBL1766227) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(cc12)[N+]([O-])=O)C(=O)NCCN1CCCC1 Show InChI InChI=1S/C23H26N4O5S/c1-15-11-16(2)13-18(12-15)33(31,32)22-19-14-17(27(29)30)5-6-20(19)25-21(22)23(28)24-7-10-26-8-3-4-9-26/h5-6,11-14,25H,3-4,7-10H2,1-2H3,(H,24,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483700 (CHEMBL1766232) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)c(F)c12)C(=O)NCCN1CCOCC1 Show InChI InChI=1S/C23H25ClFN3O4S/c1-14-11-15(2)13-16(12-14)33(30,31)22-19-18(4-3-17(24)20(19)25)27-21(22)23(29)26-5-6-28-7-9-32-10-8-28/h3-4,11-13,27H,5-10H2,1-2H3,(H,26,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	711	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483701 (CHEMBL1766320) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(cc12)[N+]([O-])=O)C(=O)NCCOc1ccccc1 Show InChI InChI=1S/C25H23N3O6S/c1-16-12-17(2)14-20(13-16)35(32,33)24-21-15-18(28(30)31)8-9-22(21)27-23(24)25(29)26-10-11-34-19-6-4-3-5-7-19/h3-9,12-15,27H,10-11H2,1-2H3,(H,26,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483678 (CHEMBL1766222) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Br)cc12)C(=O)NCc1ccccc1 Show InChI InChI=1S/C24H21BrN2O3S/c1-15-10-16(2)12-19(11-15)31(29,30)23-20-13-18(25)8-9-21(20)27-22(23)24(28)26-14-17-6-4-3-5-7-17/h3-13,27H,14H2,1-2H3,(H,26,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483703 (CHEMBL1766241) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)cc12)C(=O)NCCOc1ccccc1 Show InChI InChI=1S/C25H23ClN2O4S/c1-16-12-17(2)14-20(13-16)33(30,31)24-21-15-18(26)8-9-22(21)28-23(24)25(29)27-10-11-32-19-6-4-3-5-7-19/h3-9,12-15,28H,10-11H2,1-2H3,(H,27,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483704 (CHEMBL1766242) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Br)cc12)C(=O)NCCOc1ccccc1 Show InChI InChI=1S/C25H23BrN2O4S/c1-16-12-17(2)14-20(13-16)33(30,31)24-21-15-18(26)8-9-22(21)28-23(24)25(29)27-10-11-32-19-6-4-3-5-7-19/h3-9,12-15,28H,10-11H2,1-2H3,(H,27,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair