Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50352039![]() (CHEMBL1823817) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutical Research& Development L.L.C. Curated by ChEMBL | Assay Description Antagonist activity against human P2X7 receptor assessed as inhibition of IL-1beta production by cell based assay | Bioorg Med Chem Lett 25: 3157-63 (2015) Article DOI: 10.1016/j.bmcl.2015.06.004 BindingDB Entry DOI: 10.7270/Q2BV7JD0 | |||||||||||
More data for this Ligand-Target Pair |