Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with all data for assayid = 4 entry = 50001606   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Rattus norvegicus (rat))	BDBM50287311 (CHEMBL4176968) Show SMILES CC[C@@]1(CC(O)=O)CCc2cc(ccc2C1=O)-c1ccc(NC(=O)Nc2cccc(c2)C(F)(F)F)cc1 |r| Show InChI InChI=1S/C28H25F3N2O4/c1-2-27(16-24(34)35)13-12-19-14-18(8-11-23(19)25(27)36)17-6-9-21(10-7-17)32-26(37)33-22-5-3-4-20(15-22)28(29,30)31/h3-11,14-15H,2,12-13,16H2,1H3,(H,34,35)(H2,32,33,37)/t27-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant rat DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA as...				ACS Med Chem Lett 9: 103-108 (2018) Article DOI: 10.1021/acsmedchemlett.7b00450 BindingDB Entry DOI: 10.7270/Q2V127C9
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Rattus norvegicus (rat))	BDBM50287389 (CHEMBL4174767) Show SMILES CC[C@@]1(CC(O)=O)CCc2cc(ccc2C1=O)-c1ccc(NC(=O)Nc2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C27H25ClN2O4/c1-2-27(16-24(31)32)14-13-19-15-18(5-12-23(19)25(27)33)17-3-8-21(9-4-17)29-26(34)30-22-10-6-20(28)7-11-22/h3-12,15H,2,13-14,16H2,1H3,(H,31,32)(H2,29,30,34)/t27-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant rat DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA as...				ACS Med Chem Lett 9: 103-108 (2018) Article DOI: 10.1021/acsmedchemlett.7b00450 BindingDB Entry DOI: 10.7270/Q2V127C9
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Rattus norvegicus (rat))	BDBM50287313 (CHEMBL4168991) Show SMILES CCC1(CC(O)=O)CCc2cc(ccc2C1=O)-c1ccc(NC(=O)Nc2cccc(c2)C(F)(F)F)cc1 Show InChI InChI=1S/C28H25F3N2O4/c1-2-27(16-24(34)35)13-12-19-14-18(8-11-23(19)25(27)36)17-6-9-21(10-7-17)32-26(37)33-22-5-3-4-20(15-22)28(29,30)31/h3-11,14-15H,2,12-13,16H2,1H3,(H,34,35)(H2,32,33,37)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant rat DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA as...				ACS Med Chem Lett 9: 103-108 (2018) Article DOI: 10.1021/acsmedchemlett.7b00450 BindingDB Entry DOI: 10.7270/Q2V127C9
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Rattus norvegicus (rat))	BDBM50287320 (CHEMBL4166344) Show SMILES CC[C@]1(CC(O)=O)CCc2cc(ccc2C1=O)-c1ccc(NC(=O)Nc2cccc(c2)C(F)(F)F)cc1 |r| Show InChI InChI=1S/C27H35ClN2OS/c1-18(2)20-10-13-23-22(14-20)25(32-26(3,4)5)24(15-27(6,7)17-29-31)30(23)16-19-8-11-21(28)12-9-19/h8-14,18H,15-17H2,1-7H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant rat DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA as...				ACS Med Chem Lett 9: 103-108 (2018) Article DOI: 10.1021/acsmedchemlett.7b00450 BindingDB Entry DOI: 10.7270/Q2V127C9
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Rattus norvegicus (rat))	BDBM50287330 (CHEMBL4166868) Show SMILES CC[C@]1(CC(O)=O)CCc2cc(ccc2C1=O)-c1ccc(NC(=O)Nc2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C27H25ClN2O4/c1-2-27(16-24(31)32)14-13-19-15-18(5-12-23(19)25(27)33)17-3-8-21(9-4-17)29-26(34)30-22-10-6-20(28)7-11-22/h3-12,15H,2,13-14,16H2,1H3,(H,31,32)(H2,29,30,34)/t27-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant rat DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA as...				ACS Med Chem Lett 9: 103-108 (2018) Article DOI: 10.1021/acsmedchemlett.7b00450 BindingDB Entry DOI: 10.7270/Q2V127C9
					More data for this Ligand-Target Pair