Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM368552![]() (N-(1H-pyrazolo[4,3-b] pyridin- 3-yl)isoquinolin-6-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human plasmin using pyroGlu-Phe-Lys-pNA.HCl | Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM368542![]() (1-(1H-pyrazol-1-yl)-N- (1H- pyrazolo[4,3-b]pyridin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human plasmin using pyroGlu-Phe-Lys-pNA.HCl | Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM368526![]() (1-(difluoromethyl)-N- (1H-pyrazolo [4,3-b]pyridin-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human urine urokinase using L-PyroGlu-Gly-Arg-pNA.HCl substrate at 5 uM | Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H | |||||||||||
More data for this Ligand-Target Pair |