Compile Data Set for Download or QSAR

Found 28 hits Enz. Inhib. hit(s) with all data for assayid = 5 entry = 50013706   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50568739 (CHEMBL4856059) Show SMILES C[C@@H](NC(=O)\N=C(/N)NCCCc1sc(N)nc1C)c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	7.60	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50568777 (CHEMBL4845733) Show SMILES C[C@H](CNC(=S)\N=C(/N)NCCCc1sc(N)nc1C)c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	148	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50568741 (CHEMBL4875600) Show SMILES CC(NC(=O)\N=C(/N)NCCCc1sc(N)nc1C)c1cccc(F)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50121205 (CHEBI:18295 | Histamine) Show SMILES NCCc1c[nH]cn1 Show InChI InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	n/a	n/a	692	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50568744 (CHEMBL4853668) Show SMILES CCCCCCNC(=O)\N=C(/N)NCCCc1sc(N)nc1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50568747 (CHEMBL4876025) Show SMILES Cc1nc(N)sc1CCCN\C(N)=N\C(=O)NC(c1ccccc1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50568748 (CHEMBL4867962) Show SMILES C[C@H](NC(=O)\N=C(/N)NCCCc1sc(N)nc1C)c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50568749 (CHEMBL4850448) Show SMILES Cc1nc(N)sc1CCCN\C(N)=N\C(=O)NC(c1ccccc1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	48	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50568750 (CHEMBL4870510) Show SMILES CCC(NC(=O)\N=C(/N)NCCCc1sc(N)nc1C)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50568751 (CHEMBL4858849) Show SMILES CC(C)C(NC(=O)\N=C(/N)NCCCc1sc(N)nc1C)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	35	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50568752 (CHEMBL4869194) Show SMILES CC(NC(=O)\N=C(/N)NCCCc1sc(N)nc1C)c1ccc(C)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50568753 (CHEMBL4848697) Show SMILES CC(NC(=O)\N=C(/N)NCCCc1sc(N)nc1C)c1ccc(F)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50568754 (CHEMBL4863347) Show SMILES CC(NC(=O)\N=C(/N)NCCCc1sc(N)nc1C)c1ccc(Cl)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50568755 (CHEMBL4876267) Show SMILES CC(NC(=O)\N=C(/N)NCCCc1sc(N)nc1C)c1ccc(Br)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50568756 (CHEMBL4848026) Show SMILES COc1ccc(cc1)C(C)NC(=O)\N=C(/N)NCCCc1sc(N)nc1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	38	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50568757 (CHEMBL4863523) Show SMILES CC(NC(=O)\N=C(/N)NCCCc1sc(N)nc1C)c1ccc(OC(F)(F)F)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	724	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50568758 (CHEMBL4864852) Show SMILES CC(NC(=O)\N=C(/N)NCCCc1sc(N)nc1C)c1ccccc1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50568759 (CHEMBL4865965) Show SMILES Cc1nc(N)sc1CCCN\C(N)=N\C(=O)NCc1ccco1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50568760 (CHEMBL4846380) Show SMILES CC(NC(=O)\N=C(/N)NCCCc1sc(N)nc1C)c1ccco1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	9.80	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50568761 (CHEMBL4861704) Show SMILES CC(NC(=O)\N=C(/N)NCCCc1sc(N)nc1C)c1cccs1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50568762 (CHEMBL4866734) Show SMILES Cc1nc(N)sc1CCCN\C(N)=N\C(=O)NCC(c1ccccc1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	174	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50568763 (CHEMBL4852212) Show SMILES C[C@@H](CNC(=O)\N=C(/N)NCCCc1sc(N)nc1C)c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50568764 (CHEMBL4869389) Show SMILES C[C@H](CNC(=O)\N=C(/N)NCCCc1sc(N)nc1C)c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50568772 (CHEMBL4856602) Show SMILES Cc1nc(N)sc1CCCN\C(N)=N\C(=S)NC(c1ccccc1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	66	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50568773 (CHEMBL4853772) Show SMILES C[C@@H](NC(=S)\N=C(/N)NCCCc1sc(N)nc1C)c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	89	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50568774 (CHEMBL4854278) Show SMILES C[C@H](NC(=S)\N=C(/N)NCCCc1sc(N)nc1C)c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	224	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50568776 (CHEMBL4850490) Show SMILES C[C@@H](CNC(=S)\N=C(/N)NCCCc1sc(N)nc1C)c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	490	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50568740 (CHEMBL4860528) Show SMILES CCCCCNC(=O)\N=C(/N)NCCCc1sc(N)nc1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.80	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at guinea pig right atrium histamine H2 receptor assessed as increase in heart rate incubated for 30 mins in presence of cimetidine				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113190 BindingDB Entry DOI: 10.7270/Q2TF0245
					More data for this Ligand-Target Pair