Compile Data Set for Download or QSAR

Found 26 hits Enz. Inhib. hit(s) with all data for assayid = 5 entry = 50033363   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50343920 (4-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenoxy)aniline | ...) Show SMILES Nc1ccc(Oc2ccc(OCCN3CCCC3)cc2)cc1 Show InChI InChI=1S/C18H22N2O2/c19-15-3-5-17(6-4-15)22-18-9-7-16(8-10-18)21-14-13-20-11-1-2-12-20/h3-10H,1-2,11-14,19H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50343918 (2-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenoxy)aniline | ...) Show SMILES Nc1ccccc1Oc1ccc(OCCN2CCCC2)cc1 Show InChI InChI=1S/C18H22N2O2/c19-17-5-1-2-6-18(17)22-16-9-7-15(8-10-16)21-14-13-20-11-3-4-12-20/h1-2,5-10H,3-4,11-14,19H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50343904 (2-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenoxy)pyridine |...) Show SMILES C(CN1CCCC1)Oc1ccc(Oc2ccccn2)cc1 Show InChI InChI=1S/C17H20N2O2/c1-2-10-18-17(5-1)21-16-8-6-15(7-9-16)20-14-13-19-11-3-4-12-19/h1-2,5-10H,3-4,11-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50343917 (1-(2-(4-(4-Bromophenoxy)phenoxy)ethyl)pyrrolidine ...) Show SMILES Brc1ccc(Oc2ccc(OCCN3CCCC3)cc2)cc1 Show InChI InChI=1S/C18H20BrNO2/c19-15-3-5-17(6-4-15)22-18-9-7-16(8-10-18)21-14-13-20-11-1-2-12-20/h3-10H,1-2,11-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50343905 (4-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenoxy)pyridine |...) Show SMILES C(CN1CCCC1)Oc1ccc(Oc2ccncc2)cc1 Show InChI InChI=1S/C17H20N2O2/c1-2-12-19(11-1)13-14-20-15-3-5-16(6-4-15)21-17-7-9-18-10-8-17/h3-10H,1-2,11-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50343927 (1-(2-(4-(4-Nitrophenoxy)phenoxy)ethyl)pyrrolidine ...) Show SMILES [O-][N+](=O)c1ccc(Oc2ccc(OCCN3CCCC3)cc2)cc1 Show InChI InChI=1S/C18H20N2O4/c21-20(22)15-3-5-17(6-4-15)24-18-9-7-16(8-10-18)23-14-13-19-11-1-2-12-19/h3-10H,1-2,11-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50343916 (1-(2-(4-(4-Chlorophenoxy)phenoxy)ethyl)pyrrolidine...) Show SMILES Clc1ccc(Oc2ccc(OCCN3CCCC3)cc2)cc1 Show InChI InChI=1S/C18H20ClNO2/c19-15-3-5-17(6-4-15)22-18-9-7-16(8-10-18)21-14-13-20-11-1-2-12-20/h3-10H,1-2,11-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50343912 (1-(2-(4-(2-(Trifluoromethyl)phenoxy)phenoxy)ethyl)...) Show SMILES FC(F)(F)c1ccccc1Oc1ccc(OCCN2CCCC2)cc1 Show InChI InChI=1S/C19H20F3NO2/c20-19(21,22)17-5-1-2-6-18(17)25-16-9-7-15(8-10-16)24-14-13-23-11-3-4-12-23/h1-2,5-10H,3-4,11-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50085245 (1-[2-(4-Phenoxy-phenoxy)-ethyl]-pyrrolidine | CHEM...) Show SMILES C(CN1CCCC1)Oc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C18H21NO2/c1-2-6-17(7-3-1)21-18-10-8-16(9-11-18)20-15-14-19-12-4-5-13-19/h1-3,6-11H,4-5,12-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50343919 (3-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenoxy)aniline | ...) Show SMILES Nc1cccc(Oc2ccc(OCCN3CCCC3)cc2)c1 Show InChI InChI=1S/C18H22N2O2/c19-15-4-3-5-18(14-15)22-17-8-6-16(7-9-17)21-13-12-20-10-1-2-11-20/h3-9,14H,1-2,10-13,19H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	970	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50343915 (1-(2-(4-(4-Fluorophenoxy)phenoxy)ethyl)pyrrolidine...) Show SMILES Fc1ccc(Oc2ccc(OCCN3CCCC3)cc2)cc1 Show InChI InChI=1S/C18H20FNO2/c19-15-3-5-17(6-4-15)22-18-9-7-16(8-10-18)21-14-13-20-11-1-2-12-20/h3-10H,1-2,11-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50343926 (1-(2-(4-(3-Nitrophenoxy)phenoxy)ethyl)pyrrolidine ...) Show SMILES [O-][N+](=O)c1cccc(Oc2ccc(OCCN3CCCC3)cc2)c1 Show InChI InChI=1S/C18H20N2O4/c21-20(22)15-4-3-5-18(14-15)24-17-8-6-16(7-9-17)23-13-12-19-10-1-2-11-19/h3-9,14H,1-2,10-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50343914 (1-(2-(4-(4-(Trifluoromethyl)phenoxy)phenoxy)ethyl)...) Show SMILES FC(F)(F)c1ccc(Oc2ccc(OCCN3CCCC3)cc2)cc1 Show InChI InChI=1S/C19H20F3NO2/c20-19(21,22)15-3-5-17(6-4-15)25-18-9-7-16(8-10-18)24-14-13-23-11-1-2-12-23/h3-10H,1-2,11-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50343923 (CHEMBL1775110 | N-(4-(4-(2-(Pyrrolidin-1-yl)ethoxy...) Show SMILES CS(=O)(=O)Nc1ccc(Oc2ccc(OCCN3CCCC3)cc2)cc1 Show InChI InChI=1S/C19H24N2O4S/c1-26(22,23)20-16-4-6-18(7-5-16)25-19-10-8-17(9-11-19)24-15-14-21-12-2-3-13-21/h4-11,20H,2-3,12-15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50343925 (1-(2-(4-(2-Nitrophenoxy)-phenoxy)ethyl)pyrrolidine...) Show SMILES [O-][N+](=O)c1ccccc1Oc1ccc(OCCN2CCCC2)cc1 Show InChI InChI=1S/C18H20N2O4/c21-20(22)17-5-1-2-6-18(17)24-16-9-7-15(8-10-16)23-14-13-19-11-3-4-12-19/h1-2,5-10H,3-4,11-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50343911 (3-Nitro-2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenoxy)py...) Show SMILES [O-][N+](=O)c1cccnc1Oc1ccc(OCCN2CCCC2)cc1 Show InChI InChI=1S/C17H19N3O4/c21-20(22)16-4-3-9-18-17(16)24-15-7-5-14(6-8-15)23-13-12-19-10-1-2-11-19/h3-9H,1-2,10-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50343909 (1-(2-(4-(4-(Methylsulfonyl)-2-nitrophenoxy)phenoxy...) Show SMILES CS(=O)(=O)c1ccc(Oc2ccc(OCCN3CCCC3)cc2)c(c1)[N+]([O-])=O Show InChI InChI=1S/C19H22N2O6S/c1-28(24,25)17-8-9-19(18(14-17)21(22)23)27-16-6-4-15(5-7-16)26-13-12-20-10-2-3-11-20/h4-9,14H,2-3,10-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50343908 (1-(2-(4-(4-(Methylsulfonyl)phenoxy)phenoxy)ethyl)p...) Show SMILES CS(=O)(=O)c1ccc(Oc2ccc(OCCN3CCCC3)cc2)cc1 Show InChI InChI=1S/C19H23NO4S/c1-25(21,22)19-10-8-18(9-11-19)24-17-6-4-16(5-7-17)23-15-14-20-12-2-3-13-20/h4-11H,2-3,12-15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50343907 (1-(2-(4-(3-(Methylsulfonyl)phenoxy)phenoxy)ethyl)p...) Show SMILES CS(=O)(=O)c1cccc(Oc2ccc(OCCN3CCCC3)cc2)c1 Show InChI InChI=1S/C19H23NO4S/c1-25(21,22)19-6-4-5-18(15-19)24-17-9-7-16(8-10-17)23-14-13-20-11-2-3-12-20/h4-10,15H,2-3,11-14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50343913 (1-(2-(4-(3-(Trifluoromethyl)phenoxy)phenoxy)ethyl)...) Show SMILES FC(F)(F)c1cccc(Oc2ccc(OCCN3CCCC3)cc2)c1 Show InChI InChI=1S/C19H20F3NO2/c20-19(21,22)15-4-3-5-18(14-15)25-17-8-6-16(7-9-17)24-13-12-23-10-1-2-11-23/h3-9,14H,1-2,10-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50343903 (1-(2-(4-(2,4-Dinitrophenoxy)phenoxy)ethyl)pyrrolid...) Show SMILES [O-][N+](=O)c1ccc(Oc2ccc(OCCN3CCCC3)cc2)c(c1)[N+]([O-])=O Show InChI InChI=1S/C18H19N3O6/c22-20(23)14-3-8-18(17(13-14)21(24)25)27-16-6-4-15(5-7-16)26-12-11-19-9-1-2-10-19/h3-8,13H,1-2,9-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50343921 (CHEMBL1775108 | N-(Methylsulfonyl)-N-(2-(4-(2-(pyr...) Show SMILES CS(=O)(=O)N(c1ccccc1Oc1ccc(OCCN2CCCC2)cc1)S(C)(=O)=O Show InChI InChI=1S/C20H26N2O6S2/c1-29(23,24)22(30(2,25)26)19-7-3-4-8-20(19)28-18-11-9-17(10-12-18)27-16-15-21-13-5-6-14-21/h3-4,7-12H,5-6,13-16H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50343922 (CHEMBL1775109 | N-(Methylsulfonyl)-N-(3-(4-(2-(pyr...) Show SMILES CS(=O)(=O)N(c1cccc(Oc2ccc(OCCN3CCCC3)cc2)c1)S(C)(=O)=O Show InChI InChI=1S/C20H26N2O6S2/c1-29(23,24)22(30(2,25)26)17-6-5-7-20(16-17)28-19-10-8-18(9-11-19)27-15-14-21-12-3-4-13-21/h5-11,16H,3-4,12-15H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50343924 (CHEMBL1775111 | N-Methyl-N-(2-(4-(2-(pyrrolidin-1-...) Show SMILES CN(c1ccccc1Oc1ccc(OCCN2CCCC2)cc1)S(C)(=O)=O Show InChI InChI=1S/C20H26N2O4S/c1-21(27(2,23)24)19-7-3-4-8-20(19)26-18-11-9-17(10-12-18)25-16-15-22-13-5-6-14-22/h3-4,7-12H,5-6,13-16H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50343910 (2-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenoxy)pyrazine |...) Show SMILES C(CN1CCCC1)Oc1ccc(Oc2cnccn2)cc1 Show InChI InChI=1S/C16H19N3O2/c1-2-10-19(9-1)11-12-20-14-3-5-15(6-4-14)21-16-13-17-7-8-18-16/h3-8,13H,1-2,9-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50343906 (1-(2-(4-(2-(Methylsulfonyl)phenoxy)phenoxy)ethyl)p...) Show SMILES CS(=O)(=O)c1ccccc1Oc1ccc(OCCN2CCCC2)cc1 Show InChI InChI=1S/C19H23NO4S/c1-25(21,22)19-7-3-2-6-18(19)24-17-10-8-16(9-11-17)23-15-14-20-12-4-5-13-20/h2-3,6-11H,4-5,12-15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair