Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with all data for assayid = 6 entry = 50046944   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM6332 (2-Aminoquinazoline 10 | 7-methoxy-N-[4-(morpholin-...) Show SMILES COc1ccc2cnc(Nc3ccc(cc3)N3CCOCC3)nc2c1C(C)C Show InChI InChI=1S/C22H26N4O2/c1-15(2)20-19(27-3)9-4-16-14-23-22(25-21(16)20)24-17-5-7-18(8-6-17)26-10-12-28-13-11-26/h4-9,14-15H,10-13H2,1-3H3,(H,23,24,25)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tours Curated by ChEMBL					Assay Description Inhibition of CDK2/Cyclin E (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...				Eur J Med Chem 108: 701-19 (2016) Article DOI: 10.1016/j.ejmech.2015.12.023 BindingDB Entry DOI: 10.7270/Q22J6DQD
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM7644 (3-(4-{2-methylimidazo[1,2-a]pyridin-3-yl}pyrimidin...) Show SMILES Cc1nc2ccccn2c1-c1ccnc(NC(=O)Nc2ccccc2)n1 Show InChI InChI=1S/C19H16N6O/c1-13-17(25-12-6-5-9-16(25)21-13)15-10-11-20-18(23-15)24-19(26)22-14-7-3-2-4-8-14/h2-12H,1H3,(H2,20,22,23,24,26)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tours Curated by ChEMBL					Assay Description Inhibition of CDK2/Cyclin E (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...				Eur J Med Chem 108: 701-19 (2016) Article DOI: 10.1016/j.ejmech.2015.12.023 BindingDB Entry DOI: 10.7270/Q22J6DQD
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM7643 (2,2,2-trifluoro-N-(4-{2-methylimidazo[1,2-a]pyridi...) Show SMILES Cc1nc2ccccn2c1-c1ccnc(NC(=O)C(F)(F)F)n1 Show InChI InChI=1S/C14H10F3N5O/c1-8-11(22-7-3-2-4-10(22)19-8)9-5-6-18-13(20-9)21-12(23)14(15,16)17/h2-7H,1H3,(H,18,20,21,23)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tours Curated by ChEMBL					Assay Description Inhibition of CDK2/Cyclin E (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...				Eur J Med Chem 108: 701-19 (2016) Article DOI: 10.1016/j.ejmech.2015.12.023 BindingDB Entry DOI: 10.7270/Q22J6DQD
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM6943 (13-phenyl-11-azatetracyclo[8.7.0.0^{2,7}.0^{12,17}...) Show SMILES Oc1ccc2ccc3[nH]c4c(cccc4c3c2c1)-c1ccccc1 Show InChI InChI=1S/C22H15NO/c24-16-11-9-15-10-12-20-21(19(15)13-16)18-8-4-7-17(22(18)23-20)14-5-2-1-3-6-14/h1-13,23-24H	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.77E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tours Curated by ChEMBL					Assay Description Inhibition of CDK2/Cyclin E (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...				Eur J Med Chem 108: 701-19 (2016) Article DOI: 10.1016/j.ejmech.2015.12.023 BindingDB Entry DOI: 10.7270/Q22J6DQD
					More data for this Ligand-Target Pair