BindingDB PrimarySearch

Found 2 hits of ic50 for UniProtKB: P20248
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 [F82H,L83V,H84D] (Homo sapiens (Human))	BDBM5544 (4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}benz...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	103	n/a	n/a	n/a	n/a	7.5	30
University of Oxford					Assay Description In vitro kinase assay using purified enzyme, was incubated at 30 Â°C with substrate, and test compounds in the presence of 12.5 uM ATP/ [ga...				J Med Chem 49: 5470-7 (2006) Article DOI: 10.1021/jm060216x BindingDB Entry DOI: 10.7270/Q2TQ5ZS3
University of Oxford					More data for this Ligand-Target Pair				3D Structure (crystal)
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 [F82H,L83V,H84D] (Homo sapiens (Human))	BDBM12082 (((2-chloro-5-methyl-phenyl)-{6-[4-(3-(dimethylamin...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	7.5	30
University of Oxford					Assay Description In vitro kinase assay using purified enzyme, was incubated at 30 Â°C with substrate, and test compounds in the presence of 12.5 uM ATP/ [ga...				J Med Chem 49: 5470-7 (2006) Article DOI: 10.1021/jm060216x BindingDB Entry DOI: 10.7270/Q2TQ5ZS3
University of Oxford					More data for this Ligand-Target Pair				3D Structure (crystal)