Found 6 hits of ic50 for UniProtKB: P54289 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-3/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM327851
(US9663479, Formula 2 peak 2 (chiral)) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Novassay S.A.
US Patent
| Assay Description
This section describes a scintillation proximity assay (SPA) to measure [3H] gabapentin ([3H]GBP) binding to membranes containing α2δ-1 and... |
US Patent US9663479 (2017)
BindingDB Entry DOI: 10.7270/Q2FT8P41 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-3/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM327848
(US9663479, Formula 2 (Racemic))Show SMILES CCC1=C[C@@H]2[C@@H](C[C@]2(CN)Cc2nn[nH]n2)C1 |r,t:2| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Novassay S.A.
US Patent
| Assay Description
This section describes a scintillation proximity assay (SPA) to measure [3H] gabapentin ([3H]GBP) binding to membranes containing α2δ-1 and... |
US Patent US9663479 (2017)
BindingDB Entry DOI: 10.7270/Q2FT8P41 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-3/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM327849
(US9663479, Formula 3 (Racemic))Show SMILES CCC1=C[C@@H]2[C@@H](C[C@]2(CN)Cc2nc(=O)o[nH]2)C1 |r,t:2| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Novassay S.A.
US Patent
| Assay Description
This section describes a scintillation proximity assay (SPA) to measure [3H] gabapentin ([3H]GBP) binding to membranes containing α2δ-1 and... |
US Patent US9663479 (2017)
BindingDB Entry DOI: 10.7270/Q2FT8P41 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-3/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM327847
(US9663479, Pregabalin)Show InChI InChI=1S/C8H17NO2/c1-6(2)3-7(5-9)4-8(10)11/h6-7H,3-5,9H2,1-2H3,(H,10,11) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Novassay S.A.
US Patent
| Assay Description
This section describes a scintillation proximity assay (SPA) to measure [3H] gabapentin ([3H]GBP) binding to membranes containing α2δ-1 and... |
US Patent US9663479 (2017)
BindingDB Entry DOI: 10.7270/Q2FT8P41 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-3/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM327850
(US9663479, Formula 2 peak 1 (Chiral))Show SMILES CCC1=CC2C(C[C@@]2(CN)Cc2nn[nH]n2)C1 |r,t:2| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 165 | n/a | n/a | n/a | n/a | n/a | n/a |
Novassay S.A.
US Patent
| Assay Description
This section describes a scintillation proximity assay (SPA) to measure [3H] gabapentin ([3H]GBP) binding to membranes containing α2δ-1 and... |
US Patent US9663479 (2017)
BindingDB Entry DOI: 10.7270/Q2FT8P41 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-3/calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM327852
(US9663479, Formula 1 (Racemic))Show SMILES CCNC[C@]1(Cc2nnn[nH]2)C[C@H]2CC(CC)=C[C@@H]12 |r,c:17| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >500 | n/a | n/a | n/a | n/a | n/a | n/a |
Novassay S.A.
US Patent
| Assay Description
This section describes a scintillation proximity assay (SPA) to measure [3H] gabapentin ([3H]GBP) binding to membranes containing α2δ-1 and... |
US Patent US9663479 (2017)
BindingDB Entry DOI: 10.7270/Q2FT8P41 |
More data for this
Ligand-Target Pair | |
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