Compile Data Set for Download or QSAR

Found 3 hits of ic50 for UniProtKB: P03366   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein [600-1159,Y780C]/Imidazoleglycerol-phosphate dehydratase [600-1029,Y780C] (Human immunodeficiency virus type 1)	BDBM16189 (4-(3-Iodophenyl)-3-oxobutanenitrile | beta-ketonit...) Show SMILES Ic1cccc(CC(=O)CC#N)c1 Show InChI InChI=1S/C10H8INO/c11-9-3-1-2-8(6-9)7-10(13)4-5-12/h1-3,6H,4,7H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.90E+3	n/a	n/a	n/a	n/a	7.5	37
Bar Ilan University					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 50: 2370-84 (2007) Article DOI: 10.1021/jm0613121 BindingDB Entry DOI: 10.7270/Q2VM49J0
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [600-1159,Y780C]/Imidazoleglycerol-phosphate dehydratase [600-1029,Y780C] (Human immunodeficiency virus type 1)	BDBM16196 (4-(3-Bromo-4-chlorophenyl)-1H-imidazole-5-carboxam...) Show SMILES NC(=O)c1[nH]cnc1-c1ccc(Cl)c(Br)c1 Show InChI InChI=1S/C10H7BrClN3O/c11-6-3-5(1-2-7(6)12)8-9(10(13)16)15-4-14-8/h1-4H,(H2,13,16)(H,14,15)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.64E+4	n/a	n/a	n/a	n/a	7.5	37
Bar Ilan University					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 50: 2370-84 (2007) Article DOI: 10.1021/jm0613121 BindingDB Entry DOI: 10.7270/Q2VM49J0
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [600-1159,Y780C]/Imidazoleglycerol-phosphate dehydratase [600-1029,Y780C] (Human immunodeficiency virus type 1)	BDBM1434 (11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...) Show SMILES Cc1ccnc2N(C3CC3)c3ncccc3C(=O)Nc12 Show InChI InChI=1S/C15H14N4O/c1-9-6-8-17-14-12(9)18-15(20)11-3-2-7-16-13(11)19(14)10-4-5-10/h2-3,6-8,10H,4-5H2,1H3,(H,18,20)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 50: 2370-84 (2007) Article DOI: 10.1021/jm0613121 BindingDB Entry DOI: 10.7270/Q2VM49J0
					More data for this Ligand-Target Pair				3D Structure (crystal)