Compile Data Set for Download or QSAR

Found 279 hits of ic50 for UniProtKB: P08172   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477482 (5-bromo-2-(N-((1S,2R)-2-(6-fluoro-2,3-dimethylphen...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ncc(Br)cc1C(N)=O)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477418 (US10889555, Example 200A | US10889555, Example 207...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c2c1OCC[C@@]2(C)O)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477358 (6-(8-oxa-3-azabicyclo[3.2.1]octane-3-carbonyl)-5-c...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c(n1)C(=O)N1CC2CCC(C1)O2)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477305 (US10889555, Example 39 | US11634395, Example 39) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1cc(C(=O)N(C)C)c(Cl)cc1C(N)=O)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477477 (US10889555, Example 245 | US11634395, Example 245) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ncc(Cl)cc1C(N)=O)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477445 (US10889555, Example 222B | US10889555, Example 226...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c2c1OCC[C@@]2(C)O)c1n[nH]c(=O)o1)c1c(F)ccc(Br)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477519 (US10889555, Example 287 | US11634395, Example 287) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)cc1C(N)=S)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477459 (US10889555, Example 230B | US11634395, Example 230...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(F)c2[C@H](O)CCOc12)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477447 (5-fluoro-N-((1S,2R)-2-(6-fluoro-2,3-dimethylphenyl...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(F)c2c1OCC[C@]2(C)O)c1n[nH]c(=O)o1)c1c(F)ccc(Br)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477236 (US10889555, Example 1 | US11634395, Example 1) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Br)cc1C(N)=O)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477520 (US10889555, Example 288 | US11634395, Example 288) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c2N(C)CCOc12)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477552 (US10889555, Example 329 | US11634395, Example 329) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c2c1OCCC2(C)N)c1n[nH]c(=O)o1)c1c(F)ccc(Br)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477496 (2-(N-((1S,2R)-2-(3-bromo-6-fluoro-2-methylphenyl)-...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ncc(Cl)cc1C(N)=O)c1n[nH]c(=O)o1)c1c(F)ccc(Br)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477445 (US10889555, Example 222B | US10889555, Example 226...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c2c1OCC[C@@]2(C)O)c1n[nH]c(=O)o1)c1c(F)ccc(Br)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477414 (2-(N-((1S,2R)-2-(6-fluoro-2,3-dimethylphenyl)-1-(5...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1cc(ccc1C(N)=O)C(C)(C)O)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477355 (5-chloro-N-((1S,2R) 2-(6-fluoro-2,3-dimethylphenyl...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c(n1)C(=O)N1CCCC1)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477442 (5-chloro-N-((1S,2R)-2-(6-fluoro-2,3-dimethylphenyl...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c2c1OCC[C@]2(O)C(F)(F)F)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477484 (3-chloro-6-(N-((1S,2R)-2-(6-fluoro-2,3-dimethylphe...) Show SMILES CNC(=O)c1nc(ccc1Cl)S(=O)(=O)N[C@@H]([C@H](C)c1c(F)ccc(C)c1C)c1n[nH]c(=O)o1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477350 (US10889555, Example 109 | US11634395, Example 109 ...) Show SMILES COC(=O)c1nc(ccc1Cl)S(=O)(=O)N[C@@H]([C@H](C)c1c(F)ccc(C)c1C)c1n[nH]c(=O)o1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477456 (N-((1S,2R)-2-(3-chloro-6-fluoro-2-methylphenyl)-1-...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(F)c2c1OCC[C@]2(C)O)c1n[nH]c(=O)o1)c1c(F)ccc(Cl)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477415 (5-chloro-2-(N-((1S,2R)-2-(6-fluoro-2,3-dimethylphe...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1cc(c(Cl)cc1C(N)=O)C(C)(C)O)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477354 (5-chloro-N-((1S,2R)-2-(6-fluoro-2,3-dimethylphenyl...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c(n1)C(=O)N1CCOCC1)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477430 (US10889555, Example 208B) Show SMILES COc1c(ccc(Cl)c1[C@@H](C)O)S(=O)(=O)N[C@@H]([C@H](C)c1c(F)ccc(C)c1C)c1n[nH]c(=O)o1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477495 (4-(2,2-difluoroethoxy)-2-(N-((1S,2R)-2-(6-fluoro-2...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1cc(OCC(F)F)ccc1C(N)=O)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477486 (5-bromo-2-(N-((1S,2R)-2-(3-chloro-6-fluoro-2- | US...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ncc(Br)cc1C(N)=O)c1n[nH]c(=O)o1)c1c(F)ccc(Cl)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477518 (US10889555, Example 286 | US11634395, Example 286) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)cc1C(=O)NO)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477465 (US10889555, Example 235B | US11634395, Example 235...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c2[C@H](O)CCOc12)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477473 (N-((1S,2R)-2-(3-bromo-6-fluoro-2-methylphenyl)-1-(...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c2[C@@H](O)CCOc12)c1n[nH]c(=O)o1)c1c(F)ccc(Br)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477444 (N-((1S,2R)-2-(3-bromo-6-fluoro-2-methylphenyl)-1-(...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c2c1OCC[C@]2(C)O)c1n[nH]c(=O)o1)c1c(F)ccc(Br)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477357 (6-(3-oxa-8-azabicyclo[3.2.1]octane-8-carbonyl)-5-c...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c(n1)C(=O)N1C2CCC1COC2)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477269 (5-chloro-2-(N-((1S,2R)-2-(6-fluoro-2,3-dimethylphe...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)cc1C(N)=O)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477464 (5-chloro-N-((1S,2R)-2-(6-fluoro-2,3-dimethylphenyl...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c2[C@@H](O)CCOc12)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477432 (US10889555, Example 209B | US10889555, Example 228...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c2c1OCC[C@]2(C)O)c1n[nH]c(=O)o1)c1c(F)ccc(Cl)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477444 (N-((1S,2R)-2-(3-bromo-6-fluoro-2-methylphenyl)-1-(...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c2c1OCC[C@]2(C)O)c1n[nH]c(=O)o1)c1c(F)ccc(Br)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477443 (US10889555, Example 220B) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c2c1OCC[C@@]2(O)C(F)(F)F)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477425 (4-chloro-N-((1S,2R)-2-(2-fluoronaphthalene-1-yl)-1...) Show SMILES COc1c(ccc(Cl)c1C(C)O)S(=O)(=O)N[C@@H]([C@H](C)c1c(F)ccc2ccccc12)c1n[nH]c(=O)o1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477420 (US10889555, Example 200B | US10889555, Example 207...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c2c1OCC[C@]2(C)O)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477413 (US10889555, Example 196 | US11634395, Example 196) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1cc(c(F)cc1C(N)=O)C(C)(C)O)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477381 (5-chloro-N-((1S,2R)-2-(6-fluoro-2,3-dimethylphenyl...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c(n1)C(=O)N1CCC2(COC2)CC1)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477389 (8-(N-((1S,2R)-2-(3-bromo-6-fluoro-2-methylphenyl)-...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c2c1OCCC2(C)OC(C)=O)c1n[nH]c(=O)o1)c1c(F)ccc(Br)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477559 (US10889555, Example 337 | US11634395, Example 337) Show SMILES C[C@@H]([C@H](N(C)S(=O)(=O)c1ccc(Cl)cc1C(N)=O)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477485 (3-chloro-6-(N-((1S,2R)-2-(6-fluoro-2,3-dimethylphe...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c(n1)C(=O)N(C)C)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477493 (7-(N-((1S,2R)-2-(6-fluoro-2,3-dimethylphenyl)-1-(5...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1cc2OCCOc2cc1C(N)=O)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477453 (US10889555, Example 227B) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(F)c2c1OCC[C@@]2(C)O)c1n[nH]c(=O)o1)c1c(F)ccc(Br)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477564 (4-cyano-N-(1S,2R)-(6-fluoro-2,3-dimethylphenyl)-1-...) Show SMILES COc1cc(ccc1S(=O)(=O)N[C@@H]([C@H](C)c1c(F)ccc(C)c1C)c1n[nH]c(=O)o1)C#N |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477447 (5-fluoro-N-((1S,2R)-2-(6-fluoro-2,3-dimethylphenyl...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(F)c2c1OCC[C@]2(C)O)c1n[nH]c(=O)o1)c1c(F)ccc(Br)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477406 (US10889555, Example 186 | US11634395, Example 186) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(F)c(c1F)C(C)(C)O)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477475 (N-((1S,2R)-2-(6-fluoro-2,3-dimethylphenyl)-1-(5-ox...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(c2[C@@H](O)CCOc12)C(F)(F)F)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477533 (US10889555, Example 305 | US10889555, Example 306 ...) Show SMILES COc1cc(Cl)ccc1S(=O)(=O)N[C@@H]([C@H](C)c1c(F)ccc(-c2cnn(C)c2)c1C)c1n[nH]c(=O)o1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2 (Homo sapiens (Human))	BDBM477363 (N-((1S,2R)-2-(3-bromo-6-fluoro-2-methylphenyl)-1-(...) Show SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c2C(=O)CCOc12)c1n[nH]c(=O)o1)c1c(F)ccc(Br)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...				US Patent US10889555 (2021) BindingDB Entry DOI: 10.7270/Q2RR229N
					More data for this Ligand-Target Pair

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