Compile Data Set for Download or QSAR

Found 72 hits of ic50 for UniProtKB: P61964   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525707 (US11174250, Example 125) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1nc(ncc1F)N1CCOCC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525675 (US11174250, Example 93) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(ccc1F)C(=O)NC1CC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	197	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525693 (US11174250, Example 111) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(ccc1F)C(=O)N(C)C1CCCCC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	203	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525589 (US11174250, Example 7) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(CNC2CCCCC2)ccc1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	216	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525628 (US11174250, Example 46) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(ccc1F)C(=O)NC1CCCCC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525706 (US11174250, Example 124) Show SMILES CC1CN(CC(C)N1C)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(ccc1F)C(=O)NC1CCCCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	293	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525582 (US11174250, Example 32 | US11174250, Example Table...) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(ccc1F)C(=O)NC1CCCCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	332	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525627 (US11174250, Example 45) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(CNC2CCCCC2)ccc1F |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	514	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525609 (US11174250, Example 27) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(CN2CCOCC2)ccc1F |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	529	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525664 (US11174250, Example 82) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1ccc(OCC2CC2)nc1F |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	549	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525578 (US11174250, Example 73 | US11174250, Example Table...) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(CN2CCC(F)CC2)ccc1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	592	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525578 (US11174250, Example 73 | US11174250, Example Table...) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(CN2CCC(F)CC2)ccc1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	592	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525692 (US11174250, Example 110) Show SMILES CN(C1CCCCC1)C(=O)c1ccc(F)c(c1)-c1ccc(N2CCN(C)CC2)c(NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	607	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525583 (US11174250, Example 1) Show SMILES C[C@H]1CN(Cc2ccc(F)c(c2)-c2ccc(N3CCN(C)CC3)c(NC(=O)c3c[nH]c(=O)cc3C(F)(F)F)c2)C[C@@H](C)O1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	764	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525608 (US11174250, Example 26) Show SMILES CC1CN(CCN1C)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(CN2CCOCC2)ccc1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	779	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525659 (US11174250, Example 77) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(CN2CCOC(C)(C)C2)ccc1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	907	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525575 (US11174250, Example 2 | US11174250, Example Table4...) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(CN2CCOCC2)ccc1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	939	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525575 (US11174250, Example 2 | US11174250, Example Table4...) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(CN2CCOCC2)ccc1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	939	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525575 (US11174250, Example 2 | US11174250, Example Table4...) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(CN2CCOCC2)ccc1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	939	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525585 (US11174250, Example 3) Show SMILES COCOc1cc(F)c(cc1C(=O)NC(C)(C)CC(C)(C)C)-c1ccc(N2CCN(C)CC2)c(NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	966	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525672 (US11174250, Example 90) Show SMILES CNC(=O)c1ccc(F)c(c1)-c1ccc(N2C[C@H](C)N(C)[C@H](C)C2)c(NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)c1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525648 (US11174250, Example 66) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(CN2CCN(CC3CC3)CC2)ccc1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525652 (US11174250, Example 70) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(CN2CCC(CC2)N2CCOCC2)ccc1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525649 (US11174250, Example 67) Show SMILES CN(Cc1ccc(F)c(c1)-c1ccc(N2CCN(C)CC2)c(NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)c1)C1CCCCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525619 (US11174250, Example 37) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(CNC2CCOCC2)ccc1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525642 (US11174250, Example 60) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(CN2CCOCC2)cnc1F |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525598 (US11174250, Example 16) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1ccc(OCC2CC2)nc1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525590 (US11174250, Example 8) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1ccc(OC2CCOCC2)nc1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525631 (US11174250, Example 49) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)F)-c1cc(CN2CCOCC2)ccc1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525613 (US11174250, Example 31) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(OC2CCOCC2)ncc1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525656 (US11174250, Example 74) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(CN2C3CC2COC3)ccc1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525632 (US11174250, Example 50) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(OCC2CC2)ncc1F |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525650 (US11174250, Example 68) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(CN2CCN(Cc3ccc(F)cc3)CC2)ccc1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525581 (US11174250, Example 116 | US11174250, Example Tabl...) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(ccc1Cl)C(=O)NC1CCCCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525658 (US11174250, Example 76) Show SMILES CN(Cc1ccc(F)c(c1)-c1ccc(N2CCN(C)CC2)c(NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)c1)[C@H]1CCOC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525653 (US11174250, Example 71) Show SMILES CN(C)[C@@H]1CCN(Cc2ccc(F)c(c2)-c2ccc(N3CCN(C)CC3)c(NC(=O)c3c[nH]c(=O)cc3C(F)(F)F)c2)C1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525657 (US11174250, Example 75) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(CN2CC[C@H](C2)S(C)(=O)=O)ccc1F |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525695 (US11174250, Example 113) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(CN(C)C2COC2)c(F)cc1F |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525597 (US11174250, Example 15) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(OCC2CC2)ncc1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525624 (US11174250, Example 42) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cnc(OCC[Si](C)(C)C)cc1C(F)(F)F)-c1cc(CNC2CCC(F)(F)CC2)ccc1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525617 (US11174250, Example 35) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(CNC(C)(C)C)ccc1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525629 (US11174250, Example 47) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(ccc1F)C(=O)N1CCOCC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525621 (US11174250, Example 39) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1ccnc(N2CCOCC2)c1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525588 (US11174250, Example 6) Show SMILES CC(C)COc1ccc(F)c(c1)-c1ccc(N2CCN(C)CC2)c(NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525678 (US11174250, Example 96) Show SMILES C[C@H]1CN(CCN1C)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1ncccc1F |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525651 (US11174250, Example 69) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(CN2CC[C@@H](O)C2)ccc1F |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525625 (US11174250, Example 43) Show SMILES CN(Cc1ccc(F)c(c1)-c1ccc(N2CCN(C)CC2)c(NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)c1)C1COC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525669 (US11174250, Example 87) Show SMILES CN(C)C1CCN(C1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(CN2CCOCC2)ccc1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525681 (US11174250, Example 99) Show SMILES CN1CCN(CC1)c1ccc(c(F)c1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(CN2CCOCC2)ccc1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.99E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534] (Human-Homo sapiens (Human))	BDBM525620 (US11174250, Example 38) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1ccc(CN2CCOCC2)cc1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.99E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K
					More data for this Ligand-Target Pair

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