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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for UniProtKB: P49356   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dimer of Protein farnesyltransferase subunit beta


(Homo sapiens (Human))		BDBM50143596
PNG
(30-oxo-(1R,5R)-19-oxa-2,6,10,12-tetraazahexacyclo[...)
Show SMILES O=C1C2CCN1[C@@H]1CCCc3ccc(Oc4cc(Cn5cncc5CN2)ccc4C#N)cc13
Show InChI InChI=1S/C26H25N5O2/c27-12-19-5-4-17-10-25(19)33-21-7-6-18-2-1-3-24(22(18)11-21)31-9-8-23(26(31)32)29-14-20-13-28-16-30(20)15-17/h4-7,10-11,13,16,23-24,29H,1-3,8-9,14-15H2/t23?,24-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 0.180n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Effective concentration required to inhibit HDJ2 farnesylation in PSN-1 cells

J Med Chem 47: 1869-78 (2004)


Article DOI: 10.1021/jm0305467
BindingDB Entry DOI: 10.7270/Q2RX9CVX
More data for this
Ligand-Target Pair