Found 5 hits of ki for UniProtKB: P29703 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Saccharomyces cerevisiae (Baker's yeast)) | BDBM50289981
(Prenyl pyrophosphate analogue | {[(2E,6E)-8-[(3-be...)Show SMILES C\C(CC\C=C(/C)COC(=O)c1cccc(c1)C(=O)c1ccccc1)=C/COP([O-])(=O)OP([O-])([O-])=O Show InChI InChI=1S/C24H28O10P2/c1-18(14-15-33-36(30,31)34-35(27,28)29)8-6-9-19(2)17-32-24(26)22-13-7-12-21(16-22)23(25)20-10-4-3-5-11-20/h3-5,7,9-14,16H,6,8,15,17H2,1-2H3,(H,30,31)(H2,27,28,29)/p-3/b18-14+,19-9+ | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| KEGG
PC cid
PC sid
UniChem
Similars
| Article
| 380 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of yeast Farnesyl transferase |
Bioorg Med Chem Lett 7: 2125-2130 (1997)
Article DOI: 10.1016/S0960-894X(97)00373-9
BindingDB Entry DOI: 10.7270/Q2542P3X |
More data for this
Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Saccharomyces cerevisiae (Baker's yeast)) | BDBM50289982
(Prenyl pyrophosphate analogue)Show SMILES C\C(CC\C=C(/C)CNC(=O)c1cccc(c1)C(=O)c1ccccc1)=C/COP([O-])(=O)OP([O-])([O-])=O Show InChI InChI=1S/C24H29NO9P2/c1-18(14-15-33-36(31,32)34-35(28,29)30)8-6-9-19(2)17-25-24(27)22-13-7-12-21(16-22)23(26)20-10-4-3-5-11-20/h3-5,7,9-14,16H,6,8,15,17H2,1-2H3,(H,25,27)(H,31,32)(H2,28,29,30)/p-3/b18-14+,19-9+ | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
Similars
| Article
| 700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of yeast Farnesyl transferase |
Bioorg Med Chem Lett 7: 2125-2130 (1997)
Article DOI: 10.1016/S0960-894X(97)00373-9
BindingDB Entry DOI: 10.7270/Q2542P3X |
More data for this
Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Saccharomyces cerevisiae (Baker's yeast)) | BDBM50289979
(Prenyl pyrophosphate analogue | {[(2E)-4-[(3-benzo...)Show SMILES C\C(COC(=O)c1cccc(c1)C(=O)c1ccccc1)=C/COP([O-])(=O)OP([O-])([O-])=O Show InChI InChI=1S/C19H20O10P2/c1-14(10-11-28-31(25,26)29-30(22,23)24)13-27-19(21)17-9-5-8-16(12-17)18(20)15-6-3-2-4-7-15/h2-10,12H,11,13H2,1H3,(H,25,26)(H2,22,23,24)/p-3/b14-10+ | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
Similars
| Article
| 960 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of yeast Farnesyl transferase |
Bioorg Med Chem Lett 7: 2125-2130 (1997)
Article DOI: 10.1016/S0960-894X(97)00373-9
BindingDB Entry DOI: 10.7270/Q2542P3X |
More data for this
Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Saccharomyces cerevisiae (Baker's yeast)) | BDBM50289978
(Prenyl pyrophosphate analogue | {[(2E)-4-[(3-benzo...)Show SMILES C\C(CNC(=O)c1cccc(c1)C(=O)c1ccccc1)=C/COP([O-])(=O)OP([O-])([O-])=O Show InChI InChI=1S/C19H21NO9P2/c1-14(10-11-28-31(26,27)29-30(23,24)25)13-20-19(22)17-9-5-8-16(12-17)18(21)15-6-3-2-4-7-15/h2-10,12H,11,13H2,1H3,(H,20,22)(H,26,27)(H2,23,24,25)/p-3/b14-10+ | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
Similars
| Article
| 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of yeast Farnesyl transferase |
Bioorg Med Chem Lett 7: 2125-2130 (1997)
Article DOI: 10.1016/S0960-894X(97)00373-9
BindingDB Entry DOI: 10.7270/Q2542P3X |
More data for this
Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Saccharomyces cerevisiae (Baker's yeast)) | BDBM50144314
((2E,4E,6E,8E)-3,7,11-trimethyldodeca-2,4,6,8,10-pe...)Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]=[#6]/[#6](/[#6])=[#6]/[#6]=[#6]/[#6](/[#6])=[#6]/[#6]-[#8]P([#8])(=O)[#8]P([#8])([#8])=O Show InChI InChI=1S/C15H24O7P2/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-21-24(19,20)22-23(16,17)18/h5-11H,12H2,1-4H3,(H,19,20)(H2,16,17,18)/b8-5+,10-6+,14-9+,15-11+ | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 8.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Utah
Curated by ChEMBL
| Assay Description
Dissociation constant against yeast farnesyltransferase |
Bioorg Med Chem Lett 14: 2137-40 (2004)
Article DOI: 10.1016/j.bmcl.2004.02.077
BindingDB Entry DOI: 10.7270/Q2S181Z3 |
More data for this
Ligand-Target Pair | |
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