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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for UniProtKB: P17787   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-2


(Homo sapiens (Human))		BDBM50459884
PNG
(CHEMBL4228846)
Show SMILES Brc1cccc2cc(sc12)C(=O)N[C@@H]1CCCNC1 |r|
Show InChI InChI=1S/C14H15BrN2OS/c15-11-5-1-3-9-7-12(19-13(9)11)14(18)17-10-4-2-6-16-8-10/h1,3,5,7,10,16H,2,4,6,8H2,(H,17,18)/t10-/m1/s1
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MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 660n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human alpha2beta2 nAChR expressed in HEK cells preincubated for 15 mins followed by dihydro-beta-erythroidine hydro...

Bioorg Med Chem Lett 27: 3207-3218 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.073
BindingDB Entry DOI: 10.7270/Q2MC92NR
More data for this
Ligand-Target Pair