Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat)) | BDBM81977 (CAS_79055-68-8 | CB3371309 | D-AP5 | D-APV) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Eastern Finland Curated by ChEMBL | Assay Description Antagonist activity at recombinant rat GluN1a/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glycine/glutamate-mediated current... | J Med Chem 60: 9885-9904 (2017) Article DOI: 10.1021/acs.jmedchem.7b01624 BindingDB Entry DOI: 10.7270/Q21R6SXD | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat)) | BDBM50246910 (CHEMBL4084540) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 4.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Eastern Finland Curated by ChEMBL | Assay Description Antagonist activity at recombinant rat GluN1a/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glycine/glutamate-mediated current... | J Med Chem 60: 9885-9904 (2017) Article DOI: 10.1021/acs.jmedchem.7b01624 BindingDB Entry DOI: 10.7270/Q21R6SXD | |||||||||||
More data for this Ligand-Target Pair |