Compile Data Set for Download or QSAR

Found 25 hits of ic50 for UniProtKB: P22002   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM81939 (CAS_52-53-9 | NSC_62969 | VERAPAMIL) Show SMILES COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC Show InChI InChI=1S/C27H38N2O4/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6/h9-12,17-18,20H,8,13-16H2,1-7H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
Vietnam Academy of Science and Technology Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of 60 mM K+-induced contraction				J Nat Prod 77: 1586-93 (2014) Article DOI: 10.1021/np500076v BindingDB Entry DOI: 10.7270/Q26H4K1N
					More data for this Ligand-Target Pair				3D Structure (crystal)
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM81939 (CAS_52-53-9 | NSC_62969 | VERAPAMIL) Show SMILES COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC Show InChI InChI=1S/C27H38N2O4/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6/h9-12,17-18,20H,8,13-16H2,1-7H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
Vietnam Academy of Science and Technology Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of phenylephrine-induced contraction				J Nat Prod 77: 1586-93 (2014) Article DOI: 10.1021/np500076v BindingDB Entry DOI: 10.7270/Q26H4K1N
					More data for this Ligand-Target Pair				3D Structure (crystal)
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM81939 (CAS_52-53-9 | NSC_62969 | VERAPAMIL) Show SMILES COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC Show InChI InChI=1S/C27H38N2O4/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6/h9-12,17-18,20H,8,13-16H2,1-7H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	481	n/a	n/a	n/a	n/a	n/a	n/a
Vietnam Academy of Science and Technology Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel in Wistar rat aorta rings assessed as reduction in L-type Ba(2+) current at Vh of -50 mV				J Nat Prod 77: 1586-93 (2014) Article DOI: 10.1021/np500076v BindingDB Entry DOI: 10.7270/Q26H4K1N
					More data for this Ligand-Target Pair				3D Structure (crystal)
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50280989 (2,6-dimethyl-5-methyloxycarbonyl-4-(3-nitrophenyl)...) Show SMILES COC(=O)C1[C@@H](C(C(=O)OC(=[OH+])C2=C(C)N=C(C)C([C@H]2c2cccc(c2)[N+]([O-])=O)=C([O-])OC)=C(C)N=C1C)c1cccc(c1)[N+]([O-])=O |w:29.31,c:12,37,t:15,34| Show InChI InChI=1S/C32H30N4O11/c1-15-23(29(37)45-5)27(19-9-7-11-21(13-19)35(41)42)25(17(3)33-15)31(39)47-32(40)26-18(4)34-16(2)24(30(38)46-6)28(26)20-10-8-12-22(14-20)36(43)44/h7-14,23,27-28,38H,1-6H3/t23?,27-,28+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	592	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]PN-200-110 binding to L-type calcium channels in rat cortex membranes.				Bioorg Med Chem Lett 3: 2099-2104 (1993) Article DOI: 10.1016/S0960-894X(01)81025-8 BindingDB Entry DOI: 10.7270/Q2DV1JS8
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50080302 (2-(1-azepanylmethyl)-4-{1-[3-(1-azepanylmethyl)-4-...) Show SMILES CC(CCC(O)(c1ccccc1)c1ccccc1)(c1ccc(O)c(CN2CCCCCC2)c1)c1ccc(O)c(CN2CCCCCC2)c1 Show InChI InChI=1S/C43H54N2O3/c1-42(38-20-22-40(46)34(30-38)32-44-26-12-2-3-13-27-44,39-21-23-41(47)35(31-39)33-45-28-14-4-5-15-29-45)24-25-43(48,36-16-8-6-9-17-36)37-18-10-7-11-19-37/h6-11,16-23,30-31,46-48H,2-5,12-15,24-29,32-33H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of L-type calcium channels in GH-3 rat pituitary cells				Bioorg Med Chem Lett 9: 2447-52 (1999) BindingDB Entry DOI: 10.7270/Q2FB524M
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM81939 (CAS_52-53-9 | NSC_62969 | VERAPAMIL) Show SMILES COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC Show InChI InChI=1S/C27H38N2O4/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6/h9-12,17-18,20H,8,13-16H2,1-7H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vietnam Academy of Science and Technology Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel in endothelium-intact Wistar rat aorta rings assessed as relaxation of 30 mM K+-induced contraction				J Nat Prod 77: 1586-93 (2014) Article DOI: 10.1021/np500076v BindingDB Entry DOI: 10.7270/Q26H4K1N
					More data for this Ligand-Target Pair				3D Structure (crystal)
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50080296 (2-(1-azepanylmethyl)-4-{1-[3-(1-azepanylmethyl)-4-...) Show SMILES CC(C)(c1ccc(O)c(CN2CCCCCC2)c1)c1ccc(O)c(CN2CCCCCC2)c1 Show InChI InChI=1S/C29H42N2O2/c1-29(2,25-11-13-27(32)23(19-25)21-30-15-7-3-4-8-16-30)26-12-14-28(33)24(20-26)22-31-17-9-5-6-10-18-31/h11-14,19-20,32-33H,3-10,15-18,21-22H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of L-type calcium channels in GH-3 rat pituitary cells				Bioorg Med Chem Lett 9: 2447-52 (1999) BindingDB Entry DOI: 10.7270/Q2FB524M
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50085561 (4-[2-(3-{2-[2-(3-Hydroxy-phenyl)-ethyl]-benzyloxy}...) Show SMILES CC(C)Oc1cc(OCCc2ccc(cc2)C(N)=N)cc(OCc2ccccc2CCc2cccc(O)c2)c1 Show InChI InChI=1S/C33H36N2O4/c1-23(2)39-32-20-30(37-17-16-24-10-14-27(15-11-24)33(34)35)19-31(21-32)38-22-28-8-4-3-7-26(28)13-12-25-6-5-9-29(36)18-25/h3-11,14-15,18-21,23,36H,12-13,16-17,22H2,1-2H3,(H3,34,35)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Neuroscience Research Centre Curated by ChEMBL					Assay Description Inhibition of L-type [Ca2+] channel (VSCC) in rat A7r5 vascular smooth muscle cells				Bioorg Med Chem Lett 10: 345-7 (2000) BindingDB Entry DOI: 10.7270/Q2PV6JKZ
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50080295 (2-(1-azepanylmethyl)-4-{1-[3-(1-azepanylmethyl)-4-...) Show SMILES CC(CCCN(Cc1ccccc1)Cc1ccccc1)(c1ccc(O)c(CN2CCCCCC2)c1)c1ccc(O)c(CN2CCCCCC2)c1 Show InChI InChI=1S/C45H59N3O2/c1-45(41-21-23-43(49)39(31-41)35-46-26-12-2-3-13-27-46,42-22-24-44(50)40(32-42)36-47-28-14-4-5-15-29-47)25-16-30-48(33-37-17-8-6-9-18-37)34-38-19-10-7-11-20-38/h6-11,17-24,31-32,49-50H,2-5,12-16,25-30,33-36H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of L-type calcium channels in GH-3 rat pituitary cells				Bioorg Med Chem Lett 9: 2447-52 (1999) BindingDB Entry DOI: 10.7270/Q2FB524M
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50085560 (4-[2-(3-{2-[2-(4-Hydroxy-phenyl)-ethyl]-benzyloxy}...) Show SMILES CC(C)Oc1cc(OCCc2ccc(cc2)C(N)=N)cc(OCc2ccccc2CCc2ccc(O)cc2)c1 Show InChI InChI=1S/C33H36N2O4/c1-23(2)39-32-20-30(37-18-17-25-8-13-27(14-9-25)33(34)35)19-31(21-32)38-22-28-6-4-3-5-26(28)12-7-24-10-15-29(36)16-11-24/h3-6,8-11,13-16,19-21,23,36H,7,12,17-18,22H2,1-2H3,(H3,34,35)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Neuroscience Research Centre Curated by ChEMBL					Assay Description Inhibition of L-type [Ca2+] channel (VSCC) in rat A7r5 vascular smooth muscle cells				Bioorg Med Chem Lett 10: 345-7 (2000) BindingDB Entry DOI: 10.7270/Q2PV6JKZ
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50212319 (CHEMBL18412) Show SMILES COc1ccc(cc1)C1Sc2ccccc2-n2c(CNc3ccc(F)cc3)ccc12 Show InChI InChI=1S/C25H21FN2OS/c1-29-21-13-6-17(7-14-21)25-23-15-12-20(16-27-19-10-8-18(26)9-11-19)28(23)22-4-2-3-5-24(22)30-25/h2-15,25,27H,16H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars		n/a	n/a	5.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]nitrendipine from calcium channel receptor				Citation and Details BindingDB Entry DOI: 10.7270/Q2F47RB8
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50080299 (2-(1-azepanylmethyl)-4-{1-[3-(1-azepanylmethyl)-4-...) Show SMILES CC(CCC(c1ccccc1)c1ccccc1)(c1ccc(O)c(CN2CCCCCC2)c1)c1ccc(O)c(CN2CCCCCC2)c1 Show InChI InChI=1S/C43H54N2O2/c1-43(25-24-40(34-16-8-6-9-17-34)35-18-10-7-11-19-35,38-20-22-41(46)36(30-38)32-44-26-12-2-3-13-27-44)39-21-23-42(47)37(31-39)33-45-28-14-4-5-15-29-45/h6-11,16-23,30-31,40,46-47H,2-5,12-15,24-29,32-33H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of L-type calcium channels in GH-3 rat pituitary cells				Bioorg Med Chem Lett 9: 2447-52 (1999) BindingDB Entry DOI: 10.7270/Q2FB524M
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50019968 (7-Ethyl-1,3,5-trimethyl-6,7-dihydro-1H-1,2,4,5a,8-...) Show SMILES CCC1CN2C(=N1)c1c(N=C2C)c(C)nn1C |c:5,10| Show InChI InChI=1S/C12H17N5/c1-5-9-6-17-8(3)13-10-7(2)15-16(4)11(10)12(17)14-9/h9H,5-6H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Displacement of [3H]nitrendipine from L-type [Ca2+] channel of rat brain				J Med Chem 31: 454-61 (1988) BindingDB Entry DOI: 10.7270/Q25T3JGG
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50046397 (CHEMBL3314412) Show SMILES CSC(=O)N(C)CCc1c[nH]c2ccccc12 Show InChI InChI=1S/C13H16N2OS/c1-15(13(16)17-2)8-7-10-9-14-12-6-4-3-5-11(10)12/h3-6,9,14H,7-8H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vietnam Academy of Science and Technology Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of 60 mM K+-induced contraction				J Nat Prod 77: 1586-93 (2014) Article DOI: 10.1021/np500076v BindingDB Entry DOI: 10.7270/Q26H4K1N
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50046397 (CHEMBL3314412) Show SMILES CSC(=O)N(C)CCc1c[nH]c2ccccc12 Show InChI InChI=1S/C13H16N2OS/c1-15(13(16)17-2)8-7-10-9-14-12-6-4-3-5-11(10)12/h3-6,9,14H,7-8H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vietnam Academy of Science and Technology Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of phenylephrine-induced contraction				J Nat Prod 77: 1586-93 (2014) Article DOI: 10.1021/np500076v BindingDB Entry DOI: 10.7270/Q26H4K1N
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50046397 (CHEMBL3314412) Show SMILES CSC(=O)N(C)CCc1c[nH]c2ccccc12 Show InChI InChI=1S/C13H16N2OS/c1-15(13(16)17-2)8-7-10-9-14-12-6-4-3-5-11(10)12/h3-6,9,14H,7-8H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vietnam Academy of Science and Technology Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of 30 mM K+-induced contraction				J Nat Prod 77: 1586-93 (2014) Article DOI: 10.1021/np500076v BindingDB Entry DOI: 10.7270/Q26H4K1N
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50046397 (CHEMBL3314412) Show SMILES CSC(=O)N(C)CCc1c[nH]c2ccccc12 Show InChI InChI=1S/C13H16N2OS/c1-15(13(16)17-2)8-7-10-9-14-12-6-4-3-5-11(10)12/h3-6,9,14H,7-8H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.98E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vietnam Academy of Science and Technology Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel in endothelium-intact Wistar rat aorta rings assessed as relaxation of 30 mM K+-induced contraction				J Nat Prod 77: 1586-93 (2014) Article DOI: 10.1021/np500076v BindingDB Entry DOI: 10.7270/Q26H4K1N
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50046399 (CHEMBL3314413) Show SMILES CSC(=O)NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C12H14N2OS/c1-16-12(15)13-7-6-9-8-14-11-5-3-2-4-10(9)11/h2-5,8,14H,6-7H2,1H3,(H,13,15)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vietnam Academy of Science and Technology Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of phenylephrine-induced contraction				J Nat Prod 77: 1586-93 (2014) Article DOI: 10.1021/np500076v BindingDB Entry DOI: 10.7270/Q26H4K1N
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50046399 (CHEMBL3314413) Show SMILES CSC(=O)NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C12H14N2OS/c1-16-12(15)13-7-6-9-8-14-11-5-3-2-4-10(9)11/h2-5,8,14H,6-7H2,1H3,(H,13,15)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vietnam Academy of Science and Technology Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel in endothelium-intact Wistar rat aorta rings assessed as relaxation of 30 mM K+-induced contraction				J Nat Prod 77: 1586-93 (2014) Article DOI: 10.1021/np500076v BindingDB Entry DOI: 10.7270/Q26H4K1N
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50046399 (CHEMBL3314413) Show SMILES CSC(=O)NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C12H14N2OS/c1-16-12(15)13-7-6-9-8-14-11-5-3-2-4-10(9)11/h2-5,8,14H,6-7H2,1H3,(H,13,15)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vietnam Academy of Science and Technology Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of 60 mM K+-induced contraction				J Nat Prod 77: 1586-93 (2014) Article DOI: 10.1021/np500076v BindingDB Entry DOI: 10.7270/Q26H4K1N
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50046399 (CHEMBL3314413) Show SMILES CSC(=O)NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C12H14N2OS/c1-16-12(15)13-7-6-9-8-14-11-5-3-2-4-10(9)11/h2-5,8,14H,6-7H2,1H3,(H,13,15)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26E+5	n/a	n/a	n/a	n/a	n/a	n/a
Vietnam Academy of Science and Technology Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel in endothelium-denuded Wistar rat aorta rings assessed as relaxation of 30 mM K+-induced contraction				J Nat Prod 77: 1586-93 (2014) Article DOI: 10.1021/np500076v BindingDB Entry DOI: 10.7270/Q26H4K1N
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50046397 (CHEMBL3314412) Show SMILES CSC(=O)N(C)CCc1c[nH]c2ccccc12 Show InChI InChI=1S/C13H16N2OS/c1-15(13(16)17-2)8-7-10-9-14-12-6-4-3-5-11(10)12/h3-6,9,14H,7-8H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.51E+5	n/a	n/a	n/a	n/a	n/a	n/a
Vietnam Academy of Science and Technology Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel in Wistar rat aorta rings assessed as reduction in L-type Ba(2+) current at Vh of -50 mV				J Nat Prod 77: 1586-93 (2014) Article DOI: 10.1021/np500076v BindingDB Entry DOI: 10.7270/Q26H4K1N
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50230150 (CHEMBL345052) Show SMILES OC(COc1cccc2oc(cc12)C#N)CN1CCN(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H29N3O3/c30-19-25-18-26-27(12-7-13-28(26)35-25)34-21-24(33)20-31-14-16-32(17-15-31)29(22-8-3-1-4-9-22)23-10-5-2-6-11-23/h1-13,18,24,29,33H,14-17,20-21H2	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Calcium channel binding activity against dihydropyridine receptor in rat brain cortical membranes				J Med Chem 35: 4442-9 (1992) BindingDB Entry DOI: 10.7270/Q2RJ4MQB
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50001689 (4-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy...) Show SMILES OC(COc1cccc2[nH]c(cc12)C#N)CN1CCN(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H30N4O2/c30-19-24-18-26-27(31-24)12-7-13-28(26)35-21-25(34)20-32-14-16-33(17-15-32)29(22-8-3-1-4-9-22)23-10-5-2-6-11-23/h1-13,18,25,29,31,34H,14-17,20-21H2	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	5.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Calcium channel binding activity against dihydropyridine receptor in rat brain cortical membranes				J Med Chem 35: 4442-9 (1992) BindingDB Entry DOI: 10.7270/Q2RJ4MQB
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S (Rattus norvegicus-RAT)	BDBM50230151 (CHEMBL136313) Show SMILES OC(COc1ccnc2ccccc12)CN1CCN(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H31N3O2/c33-25(22-34-28-15-16-30-27-14-8-7-13-26(27)28)21-31-17-19-32(20-18-31)29(23-9-3-1-4-10-23)24-11-5-2-6-12-24/h1-16,25,29,33H,17-22H2	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>5.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Calcium channel binding activity against dihydropyridine receptor in rat brain cortical membranes				J Med Chem 35: 4442-9 (1992) BindingDB Entry DOI: 10.7270/Q2RJ4MQB
					More data for this Ligand-Target Pair