Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Proto-oncogene tyrosine-protein kinase ROS/Sodium-dependent phosphate transport protein 2B (Homo sapiens (Human)) | BDBM50018830 (CHEMBL3286830 | US10543199, Compound PF-06463922 |...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of SLC34A2-ROS1 (unknown origin) expressed in human HCC78 cells assessed as reduction in cell viability | Citation and Details Article DOI: 10.1021/acsmedchemlett.8b00147 BindingDB Entry DOI: 10.7270/Q2D2227R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase ROS/Sodium-dependent phosphate transport protein 2B (Homo sapiens (Human)) | BDBM50306682 ((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of SLC34A2-ROS1 (unknown origin) expressed in human HCC78 cells assessed as reduction in cell viability | Citation and Details Article DOI: 10.1021/acsmedchemlett.8b00147 BindingDB Entry DOI: 10.7270/Q2D2227R | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |