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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for UniProtKB: P23743   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Diacylglycerol kinase alpha/zeta


(Homo sapiens)		BDBM50541810
PNG
(CHEMBL4645744)
Show SMILES C[C@@H]1CN([C@@H](C)CN1C(c1ccc(F)cc1)c1ccc(F)cc1)c1cc(=O)n(C)c2ccc(nc12)C#N |r|
Show InChI InChI=1S/C29H27F2N5O/c1-18-17-36(29(20-4-8-22(30)9-5-20)21-6-10-23(31)11-7-21)19(2)16-35(18)26-14-27(37)34(3)25-13-12-24(15-32)33-28(25)26/h4-14,18-19,29H,16-17H2,1-3H3/t18-,19+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

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MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 43n/an/an/an/an/an/a



Therachem Research Medilab, LLC.

Curated by ChEMBL


Assay Description
Inhibition of DGKA/DGKZ in human CD8 cells assessed as induction of CD8 activation by measuring IFNgamma level after 20 hrs by AlphaLISA assay

ACS Med Chem Lett 11: 1083-1085 (2020)


Article DOI: 10.1021/acsmedchemlett.0c00118
BindingDB Entry DOI: 10.7270/Q20868V5
More data for this
Ligand-Target Pair