Compile Data Set for Download or QSAR

Found 15 hits of ic50 for UniProtKB: P02550   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin alpha-1A/beta chain (Sus scrofa (Pig))	BDBM50095321 (2-Methoxy-5-(3,4,5-trimethoxy-benzyloxy)-benzaldeh...) Show SMILES COc1ccc(OCc2cc(OC)c(OC)c(OC)c2)cc1C=O Show InChI InChI=1S/C18H20O6/c1-20-15-6-5-14(9-13(15)10-19)24-11-12-7-16(21-2)18(23-4)17(8-12)22-3/h5-10H,11H2,1-4H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
The University of Manchester Curated by ChEMBL					Assay Description Effect on tubulin binding and the concentration required to cause 50% decrease in tubulin assembly at 350 nm.				Bioorg Med Chem Lett 11: 51-4 (2001) BindingDB Entry DOI: 10.7270/Q2C82CHT
					More data for this Ligand-Target Pair
Tubulin alpha-1A/beta chain (Sus scrofa (Pig))	BDBM50135466 (CHEMBL3752997) Show SMILES COc1cc(cc(OC)c1OC)-c1n[nH]nc1-c1cc2ccccc2s1 Show InChI InChI=1S/C19H17N3O3S/c1-23-13-8-12(9-14(24-2)19(13)25-3)17-18(21-22-20-17)16-10-11-6-4-5-7-15(11)26-16/h4-10H,1-3H3,(H,20,21,22)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Arkansas for Medical Sciences Curated by ChEMBL					Assay Description Inhibition of porcine brain tubulin polymerization by spectrophotometric analysis				Medchemcomm 6: 1535-1543 (2016) BindingDB Entry DOI: 10.7270/Q2H41T8J
					More data for this Ligand-Target Pair
Tubulin alpha-1A/beta chain (Sus scrofa (Pig))	BDBM50095321 (2-Methoxy-5-(3,4,5-trimethoxy-benzyloxy)-benzaldeh...) Show SMILES COc1ccc(OCc2cc(OC)c(OC)c(OC)c2)cc1C=O Show InChI InChI=1S/C18H20O6/c1-20-15-6-5-14(9-13(15)10-19)24-11-12-7-16(21-2)18(23-4)17(8-12)22-3/h5-10H,11H2,1-4H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Manchester Curated by ChEMBL					Assay Description Concentration required to cause 50% decrease in the binding of [3H]colchicine from purified porcine tubulin.				Bioorg Med Chem Lett 11: 51-4 (2001) BindingDB Entry DOI: 10.7270/Q2C82CHT
					More data for this Ligand-Target Pair
Tubulin alpha-1A/beta chain (Sus scrofa (Pig))	BDBM50095317 (2-Methoxy-5-(3,4,5-trimethoxy-phenoxymethyl)-pheno...) Show SMILES COc1ccc(COc2cc(OC)c(OC)c(OC)c2)cc1O Show InChI InChI=1S/C17H20O6/c1-19-14-6-5-11(7-13(14)18)10-23-12-8-15(20-2)17(22-4)16(9-12)21-3/h5-9,18H,10H2,1-4H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Manchester Curated by ChEMBL					Assay Description Effect on tubulin binding and the concentration required to cause 50% decrease in tubulin assembly at 350 nm.				Bioorg Med Chem Lett 11: 51-4 (2001) BindingDB Entry DOI: 10.7270/Q2C82CHT
					More data for this Ligand-Target Pair
Tubulin alpha-1A/beta chain (Sus scrofa (Pig))	BDBM50135464 (CHEMBL3753885) Show SMILES COc1cc(OC)cc(c1)-c1n[nH]nc1-c1c[nH]c2ccccc12 Show InChI InChI=1S/C18H16N4O2/c1-23-12-7-11(8-13(9-12)24-2)17-18(21-22-20-17)15-10-19-16-6-4-3-5-14(15)16/h3-10,19H,1-2H3,(H,20,21,22)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Arkansas for Medical Sciences Curated by ChEMBL					Assay Description Inhibition of porcine brain tubulin polymerization by spectrophotometric analysis				Medchemcomm 6: 1535-1543 (2016) BindingDB Entry DOI: 10.7270/Q2H41T8J
					More data for this Ligand-Target Pair
Tubulin alpha-1A/beta chain (Sus scrofa (Pig))	BDBM50095326 (2-Methoxy-5-(3,4,5-trimethoxy-phenoxy)-phenol | CH...) Show SMILES COc1ccc(Oc2cc(OC)c(OC)c(OC)c2)cc1O Show InChI InChI=1S/C16H18O6/c1-18-13-6-5-10(7-12(13)17)22-11-8-14(19-2)16(21-4)15(9-11)20-3/h5-9,17H,1-4H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Manchester Curated by ChEMBL					Assay Description Effect on tubulin binding and the concentration required to cause 50% decrease in tubulin assembly at 350 nm.				Bioorg Med Chem Lett 11: 51-4 (2001) BindingDB Entry DOI: 10.7270/Q2C82CHT
					More data for this Ligand-Target Pair
Tubulin alpha-1A/beta chain (Sus scrofa (Pig))	BDBM50135465 (CHEMBL3753880) Show SMILES COc1cc(cc(OC)c1OC)-c1n[nH]nc1-c1c[nH]c2ccccc12 Show InChI InChI=1S/C19H18N4O3/c1-24-15-8-11(9-16(25-2)19(15)26-3)17-18(22-23-21-17)13-10-20-14-7-5-4-6-12(13)14/h4-10,20H,1-3H3,(H,21,22,23)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Arkansas for Medical Sciences Curated by ChEMBL					Assay Description Inhibition of porcine brain tubulin polymerization by spectrophotometric analysis				Medchemcomm 6: 1535-1543 (2016) BindingDB Entry DOI: 10.7270/Q2H41T8J
					More data for this Ligand-Target Pair
Tubulin alpha-1A/beta chain (Sus scrofa (Pig))	BDBM50095320 (2-Methoxy-5-(3,4,5-trimethoxy-benzyloxy)-phenol | ...) Show SMILES COc1ccc(OCc2cc(OC)c(OC)c(OC)c2)cc1O Show InChI InChI=1S/C17H20O6/c1-19-14-6-5-12(9-13(14)18)23-10-11-7-15(20-2)17(22-4)16(8-11)21-3/h5-9,18H,10H2,1-4H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Manchester Curated by ChEMBL					Assay Description Effect on tubulin binding and the concentration required to cause 50% decrease in tubulin assembly at 350 nm.				Bioorg Med Chem Lett 11: 51-4 (2001) BindingDB Entry DOI: 10.7270/Q2C82CHT
					More data for this Ligand-Target Pair
Tubulin alpha-1A/beta chain (Sus scrofa (Pig))	BDBM50095326 (2-Methoxy-5-(3,4,5-trimethoxy-phenoxy)-phenol | CH...) Show SMILES COc1ccc(Oc2cc(OC)c(OC)c(OC)c2)cc1O Show InChI InChI=1S/C16H18O6/c1-18-13-6-5-10(7-12(13)17)22-11-8-14(19-2)16(21-4)15(9-11)20-3/h5-9,17H,1-4H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Manchester Curated by ChEMBL					Assay Description Concentration required to cause 50% decrease in the binding of [3H]colchicine from purified porcine tubulin.				Bioorg Med Chem Lett 11: 51-4 (2001) BindingDB Entry DOI: 10.7270/Q2C82CHT
					More data for this Ligand-Target Pair
Tubulin alpha-1A/beta chain (Sus scrofa (Pig))	BDBM50095317 (2-Methoxy-5-(3,4,5-trimethoxy-phenoxymethyl)-pheno...) Show SMILES COc1ccc(COc2cc(OC)c(OC)c(OC)c2)cc1O Show InChI InChI=1S/C17H20O6/c1-19-14-6-5-11(7-13(14)18)10-23-12-8-15(20-2)17(22-4)16(9-12)21-3/h5-9,18H,10H2,1-4H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Manchester Curated by ChEMBL					Assay Description Concentration required to cause 50% decrease in the binding of [3H]colchicine from purified porcine tubulin.				Bioorg Med Chem Lett 11: 51-4 (2001) BindingDB Entry DOI: 10.7270/Q2C82CHT
					More data for this Ligand-Target Pair
Tubulin alpha-1A/beta chain (Sus scrofa (Pig))	BDBM50134459 (2-(3-Hydroxy-4-methoxy-phenyl)-6,7,8-trimethoxy-ch...) Show SMILES COc1ccc(cc1O)-c1cc(=O)c2cc(OC)c(OC)c(OC)c2o1 Show InChI InChI=1S/C19H18O7/c1-22-14-6-5-10(7-13(14)21)15-9-12(20)11-8-16(23-2)18(24-3)19(25-4)17(11)26-15/h5-9,21H,1-4H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Ability to inhibit the binding of [3H]colchicine to porcine tubulin				Bioorg Med Chem Lett 13: 3759-63 (2003) BindingDB Entry DOI: 10.7270/Q2G73D48
					More data for this Ligand-Target Pair
Tubulin alpha-1A/beta chain (Sus scrofa (Pig))	BDBM50134450 (2-[1-(3-Hydroxy-4-methoxy-phenyl)-meth-(Z)-ylidene...) Show SMILES COc1ccc(\C=C2/Oc3c(cc(OC)c(OC)c3OC)C2=O)cc1O Show InChI InChI=1S/C19H18O7/c1-22-13-6-5-10(7-12(13)20)8-14-16(21)11-9-15(23-2)18(24-3)19(25-4)17(11)26-14/h5-9,20H,1-4H3/b14-8-	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Ability to inhibit the binding of [3H]colchicine to porcine tubulin				Bioorg Med Chem Lett 13: 3759-63 (2003) BindingDB Entry DOI: 10.7270/Q2G73D48
					More data for this Ligand-Target Pair
Tubulin alpha-1A/beta chain (Sus scrofa (Pig))	BDBM50095319 (2-Methoxy-5-(3,4,5-trimethoxy-phenylamino)-phenol ...) Show SMILES COc1ccc(Nc2cc(OC)c(OC)c(OC)c2)cc1O Show InChI InChI=1S/C16H19NO5/c1-19-13-6-5-10(7-12(13)18)17-11-8-14(20-2)16(22-4)15(9-11)21-3/h5-9,17-18H,1-4H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Manchester Curated by ChEMBL					Assay Description Effect on tubulin binding and the concentration required to cause 50% decrease in tubulin assembly at 350 nm.				Bioorg Med Chem Lett 11: 51-4 (2001) BindingDB Entry DOI: 10.7270/Q2C82CHT
					More data for this Ligand-Target Pair
Tubulin alpha-1A/beta chain (Sus scrofa (Pig))	BDBM50095320 (2-Methoxy-5-(3,4,5-trimethoxy-benzyloxy)-phenol | ...) Show SMILES COc1ccc(OCc2cc(OC)c(OC)c(OC)c2)cc1O Show InChI InChI=1S/C17H20O6/c1-19-14-6-5-12(9-13(14)18)23-10-11-7-15(20-2)17(22-4)16(8-11)21-3/h5-9,18H,10H2,1-4H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.26E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Manchester Curated by ChEMBL					Assay Description Concentration required to cause 50% decrease in the binding of [3H]colchicine from purified porcine tubulin.				Bioorg Med Chem Lett 11: 51-4 (2001) BindingDB Entry DOI: 10.7270/Q2C82CHT
					More data for this Ligand-Target Pair
Tubulin alpha-1A/beta chain (Sus scrofa (Pig))	BDBM50095319 (2-Methoxy-5-(3,4,5-trimethoxy-phenylamino)-phenol ...) Show SMILES COc1ccc(Nc2cc(OC)c(OC)c(OC)c2)cc1O Show InChI InChI=1S/C16H19NO5/c1-19-13-6-5-10(7-12(13)18)17-11-8-14(20-2)16(22-4)15(9-11)21-3/h5-9,17-18H,1-4H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.98E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Manchester Curated by ChEMBL					Assay Description Concentration required to cause 50% decrease in the binding of [3H]colchicine from purified porcine tubulin.				Bioorg Med Chem Lett 11: 51-4 (2001) BindingDB Entry DOI: 10.7270/Q2C82CHT
					More data for this Ligand-Target Pair