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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for UniProtKB: P18507   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gamma-aminobutyric acid receptor subunit alpha-1/gamma-2


(Homo sapiens (Human))		BDBM50507839
PNG
(PF-6305591 | Pf-06305591)
Show SMILES C[C@H]([C@H](N)c1nc2ccc(cc2[nH]1)C(C)(C)C)C(N)=O
Show InChI InChI=1S/C15H22N4O/c1-8(13(17)20)12(16)14-18-10-6-5-9(15(2,3)4)7-11(10)19-14/h5-8,12H,16H2,1-4H3,(H2,17,20)(H,18,19)/t8-,12+/m1/s1
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of GABA receptor alpha1gamma2 (unknown origin)

Bioorg Med Chem 27: 230-239 (2019)


Article DOI: 10.1016/j.bmc.2018.12.002
BindingDB Entry DOI: 10.7270/Q2ZK5KZN
More data for this
Ligand-Target Pair