BindingDB PrimarySearch

Found 6 hits of ic50 for UniProtKB: P00740
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Coagulation factor IX/VIII (Homo sapiens (Human))	BDBM50565732 (CHEMBL4782167) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human citrated plasma iXase (factor 8a-factor 9a complex) preincubated for 2 mins followed by factor 10 addition and measured after 1 m...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112796 BindingDB Entry DOI: 10.7270/Q28D0113
TBA					More data for this Ligand-Target Pair
Coagulation factor IX/VIII (Homo sapiens (Human))	BDBM50565731 (CHEMBL4786745) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human citrated plasma iXase (factor 8a-factor 9a complex) preincubated for 2 mins followed by factor 10 addition and measured after 1 m...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112796 BindingDB Entry DOI: 10.7270/Q28D0113
TBA					More data for this Ligand-Target Pair
Coagulation factor IX/VIII (Homo sapiens (Human))	BDBM50458155 (CHEMBL4210593) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	98.7	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human intrinsic factor tenase using factor-10 as substrate preincubated for 2 mins followed by substrate addition for 1 min measured ev...				Eur J Med Chem 148: 423-435 (2018) Article DOI: 10.1016/j.ejmech.2018.02.047 BindingDB Entry DOI: 10.7270/Q2M0483C
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor IX/VIII (Homo sapiens (Human))	BDBM50458157 (CHEMBL4216002) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human intrinsic factor tenase using factor-10 as substrate preincubated for 2 mins followed by substrate addition for 1 min measured ev...				Eur J Med Chem 148: 423-435 (2018) Article DOI: 10.1016/j.ejmech.2018.02.047 BindingDB Entry DOI: 10.7270/Q2M0483C
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor IX/VIII (Homo sapiens (Human))	BDBM50458156 (CHEMBL4204328) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human intrinsic factor tenase using factor-10 as substrate preincubated for 2 mins followed by substrate addition for 1 min measured ev...				Eur J Med Chem 148: 423-435 (2018) Article DOI: 10.1016/j.ejmech.2018.02.047 BindingDB Entry DOI: 10.7270/Q2M0483C
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor IX/VIII (Homo sapiens (Human))	BDBM50565730 (CHEMBL4792554) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human citrated plasma iXase (factor 8a-factor 9a complex) preincubated for 2 mins followed by factor 10 addition and measured after 1 m...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112796 BindingDB Entry DOI: 10.7270/Q28D0113
TBA					More data for this Ligand-Target Pair