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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for UniProtKB: P36506   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dual specificity mitogen-activated protein kinase kinase 1/2


(Rattus norvegicus)		BDBM50498018
PNG
(CHEMBL3326331)
Show SMILES COc1cccc(c1N)-c1cc(=O)c2cccc(NCCCO)c2o1
Show InChI InChI=1S/C19H20N2O4/c1-24-16-8-3-6-13(18(16)20)17-11-15(23)12-5-2-7-14(19(12)25-17)21-9-4-10-22/h2-3,5-8,11,21-22H,4,9-10,20H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 97n/an/an/an/an/an/a



University of Gothenburg

Curated by ChEMBL


Assay Description
Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...

Eur J Med Chem 85: 127-38 (2014)


Article DOI: 10.1016/j.ejmech.2014.07.018
BindingDB Entry DOI: 10.7270/Q2Z322NF
More data for this
Ligand-Target Pair