Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Estradiol-bound Estrogen receptor [255-595] (Homo sapiens (Human)) | BDBM217392 (CLTERHKILHRLLQE | NRBoxII) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | 7.4 | 25 |
University of Delaware | Assay Description Peptides and the ERα LBD were diluted in 1× PBS buffer [140 mM NaCl, 2.7 mM KCl, 10 mM K2HPO4, and 2 mM KH2PO4 (pH 7.4)]. Peptide concentrations... | Biochemistry 56: 1062-1074 (2017) Article DOI: 10.1021/acs.biochem.6b01020 BindingDB Entry DOI: 10.7270/Q23B5Z0G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estradiol-bound Estrogen receptor [255-595] (Homo sapiens (Human)) | BDBM217395 (CLTERHKILHR(Hse(C4F9))LQE | Leu12Hse(C4F9)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | 7.4 | 25 |
University of Delaware | Assay Description Peptides and the ERα LBD were diluted in 1× PBS buffer [140 mM NaCl, 2.7 mM KCl, 10 mM K2HPO4, and 2 mM KH2PO4 (pH 7.4)]. Peptide concentrations... | Biochemistry 56: 1062-1074 (2017) Article DOI: 10.1021/acs.biochem.6b01020 BindingDB Entry DOI: 10.7270/Q23B5Z0G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estradiol-bound Estrogen receptor [255-595] (Homo sapiens (Human)) | BDBM217393 (CLTERHK(Hse(C4F9))LHRLLQE | Ile8Hse(C4F9)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 7.10E+3 | n/a | n/a | n/a | 7.4 | 25 |
University of Delaware | Assay Description Peptides and the ERα LBD were diluted in 1× PBS buffer [140 mM NaCl, 2.7 mM KCl, 10 mM K2HPO4, and 2 mM KH2PO4 (pH 7.4)]. Peptide concentrations... | Biochemistry 56: 1062-1074 (2017) Article DOI: 10.1021/acs.biochem.6b01020 BindingDB Entry DOI: 10.7270/Q23B5Z0G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estradiol-bound Estrogen receptor [255-595] (Homo sapiens (Human)) | BDBM217394 (CLTERHKI(Hse(C4F9))HRLLQE | Leu9Hse(C4F9)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 4.30E+4 | n/a | n/a | n/a | 7.4 | 25 |
University of Delaware | Assay Description Peptides and the ERα LBD were diluted in 1× PBS buffer [140 mM NaCl, 2.7 mM KCl, 10 mM K2HPO4, and 2 mM KH2PO4 (pH 7.4)]. Peptide concentrations... | Biochemistry 56: 1062-1074 (2017) Article DOI: 10.1021/acs.biochem.6b01020 BindingDB Entry DOI: 10.7270/Q23B5Z0G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estradiol-bound Estrogen receptor [255-595] (Homo sapiens (Human)) | BDBM217396 (CLTERHKI(hyp(C4F9))HRLLQE | Leu9hyp(C4F9)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | >1.50E+5 | n/a | n/a | n/a | 7.4 | 25 |
University of Delaware | Assay Description Peptides and the ERα LBD were diluted in 1× PBS buffer [140 mM NaCl, 2.7 mM KCl, 10 mM K2HPO4, and 2 mM KH2PO4 (pH 7.4)]. Peptide concentrations... | Biochemistry 56: 1062-1074 (2017) Article DOI: 10.1021/acs.biochem.6b01020 BindingDB Entry DOI: 10.7270/Q23B5Z0G | |||||||||||
More data for this Ligand-Target Pair |