Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-2/subunit gamma-1 (Homo sapiens (Human)) | BDBM50242401 (4-hydroxy-3-(2'-hydroxybiphenyl-4-yl)-6-oxo-6,7-di...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 1.45E+4 | n/a | n/a | n/a | n/a | n/a |
Maastricht University Curated by ChEMBL | Assay Description Binding affinity to human recombinant N-terminal AVI-tagged phosphorylated AMPK alpha1beta2gamma1 expressed in Escherichia coli BL21 cells after 1 to... | J Med Chem 59: 2879-93 (2016) Article DOI: 10.1021/acs.jmedchem.5b01201 BindingDB Entry DOI: 10.7270/Q26976KB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |