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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for UniProtKB: P16056   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor/Nucleoprotein TPR


(Mus musculus)		BDBM163243
PNG
(US9062045, Comparator No. 1 (JNJ-38877605))
Show SMILES Cn1cc(cn1)-c1ccc2nnc(n2n1)C(F)(F)c1ccc2ncccc2c1
Show InChI InChI=1S/C19H13F2N7/c1-27-11-13(10-23-27)16-6-7-17-24-25-18(28(17)26-16)19(20,21)14-4-5-15-12(9-14)3-2-8-22-15/h2-11H,1H3
PDB

UniProtKB/SwissProt

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MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 8.60n/an/an/an/an/an/a



Chinese Academy of Sciences (CAS)

Curated by ChEMBL


Assay Description
Inhibition of TPR-MET in mouse BAF3 cells assessed as reduction in cell proliferation after 72 hrs by SRB or MTT assay

Eur J Med Chem 116: 239-251 (2016)


Article DOI: 10.1016/j.ejmech.2016.03.076
BindingDB Entry DOI: 10.7270/Q2P27111
More data for this
Ligand-Target Pair