Compile Data Set for Download or QSAR

Found 11 hits of ic50 for UniProtKB: P09211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutathione S-transferase P/Rho-associated protein kinase 1 [1-535] (Homo sapiens (Human))	BDBM258601 (US9493490, 6-(4-(aminomethyl)-2-chlorophenoxy)-7-i...) Show SMILES CC(C)c1c2B(O)OCc2ccc1Oc1ccc(CN)cc1Cl Show InChI InChI=1S/C17H19BClNO3/c1-10(2)16-15(6-4-12-9-22-18(21)17(12)16)23-14-5-3-11(8-20)7-13(14)19/h3-7,10,21H,8-9,20H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	59.6	n/a	n/a	n/a	n/a	n/a	25
Anacor Pharmaceuticals, Inc. US Patent					Assay Description Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...				US Patent US9493490 (2016) BindingDB Entry DOI: 10.7270/Q2R2109J
					More data for this Ligand-Target Pair
Glutathione S-transferase P/Rho-associated protein kinase 1 [1-535] (Homo sapiens (Human))	BDBM258598 (US9493490, Example 10 | US9493490, G) Show SMILES C[C@@H](N)c1ccc(Oc2ccc3COB(O)c3c2C)c(F)c1 |r| Show InChI InChI=1S/C16H17BFNO3/c1-9-14(5-4-12-8-21-17(20)16(9)12)22-15-6-3-11(10(2)19)7-13(15)18/h3-7,10,20H,8,19H2,1-2H3/t10-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	25
Anacor Pharmaceuticals, Inc. US Patent					Assay Description Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...				US Patent US9493490 (2016) BindingDB Entry DOI: 10.7270/Q2R2109J
					More data for this Ligand-Target Pair
Glutathione S-transferase P/Rho-associated protein kinase 1 [1-535] (Homo sapiens (Human))	BDBM258600 (US9493490, 6-(3-(aminomethyl)-2-fluorophenoxy)-7-m...) Show SMILES Cc1c2B(O)OCc2ccc1Oc1cccc(CN)c1F Show InChI InChI=1S/C15H15BFNO3/c1-9-12(6-5-11-8-20-16(19)14(9)11)21-13-4-2-3-10(7-18)15(13)17/h2-6,19H,7-8,18H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	247	n/a	n/a	n/a	n/a	n/a	25
Anacor Pharmaceuticals, Inc. US Patent					Assay Description Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...				US Patent US9493490 (2016) BindingDB Entry DOI: 10.7270/Q2R2109J
					More data for this Ligand-Target Pair
Glutathione S-transferase P/Rho-associated protein kinase 1 [1-535] (Homo sapiens (Human))	BDBM258592 (US9493490, 6-(4-(Aminomethyl)-2-chlorophenoxy)-7-e...) Show SMILES CCc1c2B(O)OCc2ccc1Oc1ccc(CN)cc1Cl Show InChI InChI=1S/C16H17BClNO3/c1-2-12-14(6-4-11-9-21-17(20)16(11)12)22-15-5-3-10(8-19)7-13(15)18/h3-7,20H,2,8-9,19H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	25
Anacor Pharmaceuticals, Inc. US Patent					Assay Description Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...				US Patent US9493490 (2016) BindingDB Entry DOI: 10.7270/Q2R2109J
					More data for this Ligand-Target Pair
Glutathione S-transferase P/Rho-associated protein kinase 1 [1-535] (Homo sapiens (Human))	BDBM258595 (US9493490, 6-(4-(aminomethyl)-2-fluorophenoxy)-7-m...) Show SMILES Cc1c2B(O)OCc2ccc1Oc1ccc(CN)cc1F Show InChI InChI=1S/C15H15BFNO3/c1-9-13(5-3-11-8-20-16(19)15(9)11)21-14-4-2-10(7-18)6-12(14)17/h2-6,19H,7-8,18H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	25
Anacor Pharmaceuticals, Inc. US Patent					Assay Description Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...				US Patent US9493490 (2016) BindingDB Entry DOI: 10.7270/Q2R2109J
					More data for this Ligand-Target Pair
Glutathione S-transferase P/Rho-associated protein kinase 1 [1-535] (Homo sapiens (Human))	BDBM258596 (US9493490, 6-(4-(1-aminoethyl)-2-fluorophenoxy)-7-...) Show SMILES CC(N)c1ccc(Oc2ccc3COB(O)c3c2C)c(F)c1 Show InChI InChI=1S/C16H17BFNO3/c1-9-14(5-4-12-8-21-17(20)16(9)12)22-15-6-3-11(10(2)19)7-13(15)18/h3-7,10,20H,8,19H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	25
Anacor Pharmaceuticals, Inc. US Patent					Assay Description Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...				US Patent US9493490 (2016) BindingDB Entry DOI: 10.7270/Q2R2109J
					More data for this Ligand-Target Pair
Glutathione S-transferase P/Rho-associated protein kinase 1 [1-535] (Homo sapiens (Human))	BDBM258594 (US9493490, 6-(4-(1-aminoethyl)-2-fluorophenoxy)ben...) Show SMILES CC(N)c1ccc(Oc2ccc3COB(O)c3c2)c(F)c1 Show InChI InChI=1S/C15H15BFNO3/c1-9(18)10-3-5-15(14(17)6-10)21-12-4-2-11-8-20-16(19)13(11)7-12/h2-7,9,19H,8,18H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	25
Anacor Pharmaceuticals, Inc. US Patent					Assay Description Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...				US Patent US9493490 (2016) BindingDB Entry DOI: 10.7270/Q2R2109J
					More data for this Ligand-Target Pair
Glutathione S-transferase P/Rho-associated protein kinase 1 [1-535] (Homo sapiens (Human))	BDBM258597 (US9493490, Example 9 | US9493490, F) Show SMILES C[C@H](N)c1ccc(Oc2ccc3COB(O)c3c2C)c(F)c1 |r| Show InChI InChI=1S/C16H17BFNO3/c1-9-14(5-4-12-8-21-17(20)16(9)12)22-15-6-3-11(10(2)19)7-13(15)18/h3-7,10,20H,8,19H2,1-2H3/t10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	25
Anacor Pharmaceuticals, Inc. US Patent					Assay Description Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...				US Patent US9493490 (2016) BindingDB Entry DOI: 10.7270/Q2R2109J
					More data for this Ligand-Target Pair
Glutathione S-transferase P/Rho-associated protein kinase 1 [1-535] (Homo sapiens (Human))	BDBM258599 (US9493490, Example 11 | US9493490, L | US9493490, ...) Show SMILES Cc1c2B(O)OCc2ccc1Oc1cccc(CNC(=O)OC(C)(C)C)c1F Show InChI InChI=1S/C20H23BFNO5/c1-12-15(9-8-14-11-26-21(25)17(12)14)27-16-7-5-6-13(18(16)22)10-23-19(24)28-20(2,3)4/h5-9,25H,10-11H2,1-4H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	25
Anacor Pharmaceuticals, Inc. US Patent					Assay Description Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...				US Patent US9493490 (2016) BindingDB Entry DOI: 10.7270/Q2R2109J
					More data for this Ligand-Target Pair
Glutathione S-transferase P/Rho-associated protein kinase 1 [1-535] (Homo sapiens (Human))	BDBM258593 (US9493490, 6-(4-(aminomethyl)-2-chlorophenoxy)-7-c...) Show SMILES NCc1ccc(Oc2ccc3COB(O)c3c2Cl)c(Cl)c1 Show InChI InChI=1S/C14H12BCl2NO3/c16-10-5-8(6-18)1-3-11(10)21-12-4-2-9-7-20-15(19)13(9)14(12)17/h1-5,19H,6-7,18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	25
Anacor Pharmaceuticals, Inc. US Patent					Assay Description Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...				US Patent US9493490 (2016) BindingDB Entry DOI: 10.7270/Q2R2109J
					More data for this Ligand-Target Pair
Glutathione S-transferase P/Rho-associated protein kinase 1 [1-535] (Homo sapiens (Human))	BDBM258593 (US9493490, 6-(4-(aminomethyl)-2-chlorophenoxy)-7-c...) Show SMILES NCc1ccc(Oc2ccc3COB(O)c3c2Cl)c(Cl)c1 Show InChI InChI=1S/C14H12BCl2NO3/c16-10-5-8(6-18)1-3-11(10)21-12-4-2-9-7-20-15(19)13(9)14(12)17/h1-5,19H,6-7,18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	25
Anacor Pharmaceuticals, Inc. US Patent					Assay Description Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...				US Patent US9493490 (2016) BindingDB Entry DOI: 10.7270/Q2R2109J
					More data for this Ligand-Target Pair