Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-Y/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM50528810 (CHEMBL4580787) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 256 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibition of recombinant NanoLuc-tagged CDK2/cyclin Y expressed in human HCT116 cells at 1 uM incubated for 20 to 24 hrs by by NanoBRET assay | Bioorg Med Chem Lett 29: 1985-1993 (2019) Article DOI: 10.1016/j.bmcl.2019.05.024 BindingDB Entry DOI: 10.7270/Q29P355R | |||||||||||
More data for this Ligand-Target Pair |