Found 38 hits of ki for UniProtKB: P25025 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214182
(CHEMBL438929)Show SMILES CC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CCSC)NC(C)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O Show InChI InChI=1S/C108H164N24O38S2/c1-12-62(114-103(165)78-20-15-39-130(78)107(169)76(51-133)127-98(160)72(47-59-24-28-61(138)29-25-59)123-101(163)75(50-85(148)149)125-92(154)64(30-33-81(140)141)116-100(162)74(49-84(146)147)121-89(151)54(6)112-102(164)77-19-16-40-131(77)108(170)79-21-17-41-132(79)106(168)68(37-43-172-11)113-57(9)136)90(152)118-67(36-42-171-10)93(155)122-70(44-52(2)3)96(158)117-65(31-34-82(142)143)94(156)128-86(55(7)134)104(166)119-66(32-35-83(144)145)95(157)129-87(56(8)135)105(167)126-71(45-53(4)5)97(159)124-73(48-80(110)139)99(161)115-63(18-13-14-38-109)91(153)120-69(88(111)150)46-58-22-26-60(137)27-23-58/h22-29,52-56,62-79,86-87,133-135,137-138H,12-21,30-51,109H2,1-11H3,(H2,110,139)(H2,111,150)(H,112,164)(H,113,136)(H,114,165)(H,115,161)(H,116,162)(H,117,158)(H,118,152)(H,119,166)(H,120,153)(H,121,151)(H,122,155)(H,123,163)(H,124,159)(H,125,154)(H,126,167)(H,127,160)(H,128,156)(H,129,157)(H,140,141)(H,142,143)(H,144,145)(H,146,147)(H,148,149)/t54-,55+,56+,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,86-,87-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214158
(CHEMBL441586)Show SMILES [#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#16]-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](-[#6])=O)-[#6@@H](-[#6])-[#8])-[#6@@H](-[#6])-[#8])-[#6](-[#6])-[#6])-[#6@@H](-[#6])-[#6]-[#6])-[#6@@H](-[#6])-[#8])-[#6@@H](-[#6])-[#6]-[#6])-[#6@@H](-[#6])-[#8])-[#6](-[#7])=O Show InChI InChI=1S/C137H236N46O48S/c1-23-60(10)99(106(142)204)177-119(217)80(38-43-95(198)199)169-131(229)103(68(18)185)180-110(208)66(16)158-121(219)86(54-96(200)201)174-123(221)82(50-57(4)5)170-109(207)64(14)157-111(209)72(30-26-45-151-134(143)144)160-92(193)56-155-127(225)100(61(11)24-2)178-125(223)85(53-91(141)192)173-124(222)84(52-90(140)191)172-113(211)74(32-28-47-153-136(147)148)162-112(210)73(31-27-46-152-135(145)146)163-115(213)78(36-41-93(194)195)161-108(206)65(15)159-130(228)102(67(17)184)181-120(218)79(37-42-94(196)197)165-114(212)76(34-39-88(138)189)167-129(227)101(62(12)25-3)179-128(226)98(59(8)9)176-118(216)77(35-40-89(139)190)168-132(230)104(69(19)186)182-117(215)75(33-29-48-154-137(149)150)164-116(214)81(44-49-232-22)166-122(220)83(51-58(6)7)175-133(231)105(70(20)187)183-126(224)87(55-97(202)203)171-107(205)63(13)156-71(21)188/h57-70,72-87,98-105,184-187H,23-56H2,1-22H3,(H2,138,189)(H2,139,190)(H2,140,191)(H2,141,192)(H2,142,204)(H,155,225)(H,156,188)(H,157,209)(H,158,219)(H,159,228)(H,160,193)(H,161,206)(H,162,210)(H,163,213)(H,164,214)(H,165,212)(H,166,220)(H,167,227)(H,168,230)(H,169,229)(H,170,207)(H,171,205)(H,172,211)(H,173,222)(H,174,221)(H,175,231)(H,176,216)(H,177,217)(H,178,223)(H,179,226)(H,180,208)(H,181,218)(H,182,215)(H,183,224)(H,194,195)(H,196,197)(H,198,199)(H,200,201)(H,202,203)(H4,143,144,151)(H4,145,146,152)(H4,147,148,153)(H4,149,150,154)/t60-,61-,62-,63-,64+,65-,66-,67+,68+,69+,70+,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,98-,99-,100-,101-,102-,103-,104-,105-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214157
(CHEMBL411239)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC)NC(=O)[C@@H](NC(C)=O)C(C)C)C(C)C)[C@@H](C)O)C(C)C)C(N)=O |wU:78.80,27.27,4.4,90.92,50.50,123.125,102.104,114.116,135.138,64.66,2.2,wD:110.112,82.84,141.144,19.19,31.31,39.39,8.8,73.75,152.155,(-6.35,2.08,;-6.74,3.24,;-5.73,4.39,;-4.51,4.15,;-6.2,5.86,;-5.19,7.01,;-5.67,8.47,;-6.88,8.72,;-4.65,9.62,;-5.14,11.09,;-6.64,11.4,;-7.13,12.86,;-8.64,13.18,;-9.12,14.64,;-10.33,14.89,;-8.3,15.56,;-3.14,9.31,;-2.66,7.85,;-3.48,6.93,;-1.15,7.54,;-.12,8.69,;1.39,8.37,;2.21,9.29,;1.77,7.2,;-.66,6.08,;.85,5.76,;1.66,6.68,;1.33,4.3,;2.84,3.99,;3.32,2.53,;2.51,1.61,;4.84,2.22,;5.86,3.37,;7.37,3.05,;8.4,4.2,;9.61,3.95,;5.32,.75,;6.83,.44,;7.65,1.36,;7.31,-1.02,;8.82,-1.34,;9.31,-2.8,;10.82,-3.11,;11.31,-4.57,;12.81,-4.88,;13.2,-6.06,;13.63,-3.96,;6.29,-2.17,;4.78,-1.86,;4.39,-.68,;3.75,-3.01,;2.24,-2.7,;1.76,-1.23,;2.66,.02,;1.76,1.24,;.3,.77,;-1.03,1.56,;-2.38,.77,;-2.38,-.77,;-1.03,-1.55,;.3,-.77,;4.24,-4.47,;5.75,-4.78,;6.56,-3.86,;6.23,-6.24,;5.21,-7.4,;5.7,-8.86,;4.67,-10.01,;5.16,-11.48,;4.34,-12.4,;7.74,-6.56,;8.22,-8.02,;7.41,-8.94,;9.74,-8.33,;10.56,-7.41,;10.22,-9.8,;11.73,-10.11,;12.55,-9.19,;12.22,-11.57,;13.72,-11.88,;14.21,-13.35,;13.39,-14.27,;15.72,-13.66,;16.75,-12.51,;18.26,-12.82,;18.64,-13.99,;19.08,-11.9,;16.21,-15.12,;17.72,-15.44,;18.53,-14.51,;18.2,-16.89,;17.18,-18.05,;17.66,-19.51,;18.87,-19.76,;16.85,-20.43,;19.71,-17.21,;20.19,-18.67,;19.38,-19.59,;21.7,-18.98,;22.19,-20.45,;23.7,-20.76,;24.52,-19.84,;24.18,-22.22,;23.16,-23.38,;23.65,-24.84,;22.83,-25.76,;24.85,-25.09,;25.69,-22.53,;26.18,-24,;25.36,-24.92,;27.69,-24.31,;28.17,-25.77,;29.68,-26.09,;30.5,-25.16,;30.17,-27.55,;29.15,-28.7,;29.63,-30.16,;28.61,-31.32,;27.4,-31.07,;29,-32.49,;31.68,-27.86,;32.16,-29.32,;31.34,-30.24,;33.67,-29.63,;34.16,-31.1,;35.67,-31.41,;36.69,-30.26,;38.2,-30.57,;38.68,-32.03,;39.89,-32.27,;37.66,-33.18,;36.16,-32.87,;34.69,-28.48,;34.21,-27.02,;33,-26.77,;35.23,-25.86,;36.74,-26.17,;37.55,-25.25,;34.74,-24.4,;35.77,-23.25,;36.97,-23.5,;35.28,-21.79,;36.3,-20.63,;35.81,-19.17,;34.61,-18.92,;36.63,-18.25,;33.77,-21.47,;32.95,-22.4,;33.38,-20.31,;28.71,-23.16,;28.33,-21.99,;29.92,-23.41,;11.19,-12.72,;9.99,-12.48,;11.58,-13.89,;.31,3.15,;.7,1.98,;-.9,3.4,;-7.72,6.17,;-8.54,5.25,;-8.1,7.34,)| Show InChI InChI=1S/C104H169N29O27S/c1-18-55(13)83(85(107)143)132-91(149)67(30-25-40-113-104(110)111)122-94(152)71(43-51(5)6)129-101(159)82(54(11)12)131-93(151)69(37-41-161-17)124-89(147)66(29-24-39-112-103(108)109)121-96(154)73(45-60-48-114-64-27-21-20-26-62(60)64)126-90(148)65(28-22-23-38-105)120-86(144)56(14)116-102(160)84(57(15)134)133-98(156)75(47-79(141)142)127-97(155)74(46-76(106)137)118-77(138)49-115-87(145)70(42-50(3)4)128-100(158)81(53(9)10)130-92(150)68(35-36-78(139)140)123-95(153)72(44-59-31-33-61(136)34-32-59)125-88(146)63(19-2)119-99(157)80(52(7)8)117-58(16)135/h20-21,26-27,31-34,48,50-57,63,65-75,80-84,114,134,136H,18-19,22-25,28-30,35-47,49,105H2,1-17H3,(H2,106,137)(H2,107,143)(H,115,145)(H,116,160)(H,117,135)(H,118,138)(H,119,157)(H,120,144)(H,121,154)(H,122,152)(H,123,153)(H,124,147)(H,125,146)(H,126,148)(H,127,155)(H,128,158)(H,129,159)(H,130,150)(H,131,151)(H,132,149)(H,133,156)(H,139,140)(H,141,142)(H4,108,109,112)(H4,110,111,113)/t55-,56-,57+,63-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,80-,81-,82-,83-,84-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214188
(CHEMBL216870)Show SMILES CSCC[C@H](NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C50H71N11O19S/c1-25(52-47(77)36-8-5-18-60(36)50(80)37-9-6-19-61(37)48(78)30(16-20-81-3)53-26(2)63)42(72)55-32(22-39(67)68)45(75)54-29(14-15-38(65)66)43(73)57-33(23-40(69)70)46(76)56-31(21-27-10-12-28(64)13-11-27)44(74)58-34(24-62)49(79)59-17-4-7-35(59)41(51)71/h10-13,25,29-37,62,64H,4-9,14-24H2,1-3H3,(H2,51,71)(H,52,77)(H,53,63)(H,54,75)(H,55,72)(H,56,76)(H,57,73)(H,58,74)(H,65,66)(H,67,68)(H,69,70)/t25-,29-,30-,31-,32-,33-,34-,35-,36-,37-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214188
(CHEMBL216870)Show SMILES CSCC[C@H](NC(C)=O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C50H71N11O19S/c1-25(52-47(77)36-8-5-18-60(36)50(80)37-9-6-19-61(37)48(78)30(16-20-81-3)53-26(2)63)42(72)55-32(22-39(67)68)45(75)54-29(14-15-38(65)66)43(73)57-33(23-40(69)70)46(76)56-31(21-27-10-12-28(64)13-11-27)44(74)58-34(24-62)49(79)59-17-4-7-35(59)41(51)71/h10-13,25,29-37,62,64H,4-9,14-24H2,1-3H3,(H2,51,71)(H,52,77)(H,53,63)(H,54,75)(H,55,72)(H,56,76)(H,57,73)(H,58,74)(H,65,66)(H,67,68)(H,69,70)/t25-,29-,30-,31-,32-,33-,34-,35-,36-,37-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214185
(CHEMBL412507)Show SMILES CSCC[C@H](NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C111H148N24O37S2/c1-55(2)41-69(122-104(165)77(49-89(147)148)131-107(168)79(51-91(151)152)129-99(160)71(43-60-21-12-9-13-22-60)124-106(167)78(50-90(149)150)130-101(162)73(45-62-52-114-65-24-15-14-23-64(62)65)126-96(157)67(34-39-173-6)118-58(5)137)98(159)127-74(46-84(112)139)102(163)123-70(42-59-19-10-8-11-20-59)97(158)116-56(3)93(154)115-53-85(140)119-68(35-40-174-7)109(170)135-38-18-27-83(135)111(172)134-37-17-26-82(134)108(169)117-57(4)94(155)121-75(47-87(143)144)103(164)120-66(32-33-86(141)142)95(156)128-76(48-88(145)146)105(166)125-72(44-61-28-30-63(138)31-29-61)100(161)132-80(54-136)110(171)133-36-16-25-81(133)92(113)153/h8-15,19-24,28-31,52,55-57,66-83,114,136,138H,16-18,25-27,32-51,53-54H2,1-7H3,(H2,112,139)(H2,113,153)(H,115,154)(H,116,158)(H,117,169)(H,118,137)(H,119,140)(H,120,164)(H,121,155)(H,122,165)(H,123,163)(H,124,167)(H,125,166)(H,126,157)(H,127,159)(H,128,156)(H,129,160)(H,130,162)(H,131,168)(H,132,161)(H,141,142)(H,143,144)(H,145,146)(H,147,148)(H,149,150)(H,151,152)/t56-,57-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214155
(CHEMBL413914)Show SMILES C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O |wU:85.88,69.72,5.5,wD:65.69,91.94,52.53,40.40,77.80,100.105,25.25,14.14,1.0,(10.92,-12.5,;11.99,-13.12,;13.32,-12.35,;13.32,-10.81,;12.26,-10.19,;14.66,-10.04,;15.99,-10.81,;17.32,-10.04,;18.66,-10.8,;18.66,-12.03,;19.73,-10.19,;14.66,-8.5,;15.99,-7.73,;17.06,-8.34,;16,-6.19,;14.66,-5.41,;14.67,-3.87,;13.34,-3.09,;13.34,-1.55,;12.01,-.78,;12.01,.45,;10.94,-1.39,;17.33,-5.42,;17.33,-3.88,;16.27,-3.26,;18.67,-3.11,;18.67,-1.57,;20.01,-.8,;20.01,.74,;21.35,1.51,;22.68,.74,;22.67,-.8,;21.34,-1.57,;20,-3.88,;20,-5.42,;18.93,-6.03,;21.06,-6.04,;11.98,-14.66,;13.05,-15.27,;10.65,-15.43,;10.65,-16.97,;9.31,-17.73,;7.98,-16.96,;6.64,-17.72,;5.31,-16.94,;5.32,-15.4,;4.25,-14.78,;6.66,-14.64,;7.99,-15.42,;11.98,-17.74,;13.05,-17.12,;11.98,-19.28,;13.31,-20.05,;13.31,-21.59,;11.97,-22.36,;11.83,-23.88,;10.32,-24.2,;9.55,-22.86,;10.59,-21.72,;14.65,-19.29,;14.65,-18.06,;15.98,-20.06,;16.11,-21.59,;17.62,-21.91,;18.39,-20.58,;17.37,-19.43,;17.68,-17.93,;16.76,-17.11,;19.15,-17.44,;19.46,-15.93,;18.31,-14.91,;16.85,-15.4,;16.6,-16.6,;15.92,-14.58,;20.92,-15.45,;21.84,-16.27,;21.23,-13.94,;22.7,-13.46,;23.84,-14.48,;23.53,-15.99,;22.36,-16.38,;24.45,-16.82,;23.01,-11.95,;22.09,-11.13,;24.47,-11.46,;24.79,-9.96,;23.63,-8.93,;22.47,-9.32,;26.25,-9.48,;27.17,-10.29,;26.56,-7.97,;28.03,-7.48,;29.17,-8.51,;28.92,-9.71,;28.34,-5.97,;27.42,-5.15,;29.8,-5.49,;31.03,-6.4,;32.28,-5.49,;31.8,-4.03,;30.26,-4.03,;29.34,-2.8,;29.82,-1.66,;28.11,-2.94,)| Show InChI InChI=1S/C64H91N21O19/c1-32(74-54(95)39(18-19-49(65)90)77-55(96)38(11-6-20-72-64(69)70)76-56(97)40(75-33(2)88)23-34-9-4-3-5-10-34)53(94)78-41(24-35-14-16-37(89)17-15-35)57(98)81-44(25-36-28-71-31-73-36)62(103)85-22-8-13-48(85)61(102)80-43(27-51(67)92)58(99)79-42(26-50(66)91)59(100)82-45(29-86)60(101)83-46(30-87)63(104)84-21-7-12-47(84)52(68)93/h3-5,9-10,14-17,28,31-32,38-48,86-87,89H,6-8,11-13,18-27,29-30H2,1-2H3,(H2,65,90)(H2,66,91)(H2,67,92)(H2,68,93)(H,71,73)(H,74,95)(H,75,88)(H,76,97)(H,77,96)(H,78,94)(H,79,99)(H,80,102)(H,81,98)(H,82,100)(H,83,101)(H4,69,70,72)/t32-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50213962
(CHEMBL410765)Show SMILES CSCC[C@H](NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C112H150N24O38S2/c1-55(2)41-69(122-103(165)77(49-89(149)150)131-106(168)79(51-91(153)154)129-98(160)70(42-59-19-10-8-11-20-59)123-105(167)78(50-90(151)152)130-100(162)73(45-62-52-115-65-24-15-14-23-64(62)65)126-96(158)67(34-39-175-6)118-58(5)139)97(159)127-74(46-84(113)141)101(163)125-72(43-60-21-12-9-13-22-60)107(169)133-92(57(4)138)109(171)116-53-85(142)119-68(35-40-176-7)110(172)136-38-18-27-83(136)112(174)135-37-17-26-82(135)108(170)117-56(3)94(156)121-75(47-87(145)146)102(164)120-66(32-33-86(143)144)95(157)128-76(48-88(147)148)104(166)124-71(44-61-28-30-63(140)31-29-61)99(161)132-80(54-137)111(173)134-36-16-25-81(134)93(114)155/h8-15,19-24,28-31,52,55-57,66-83,92,115,137-138,140H,16-18,25-27,32-51,53-54H2,1-7H3,(H2,113,141)(H2,114,155)(H,116,171)(H,117,170)(H,118,139)(H,119,142)(H,120,164)(H,121,156)(H,122,165)(H,123,167)(H,124,166)(H,125,163)(H,126,158)(H,127,159)(H,128,157)(H,129,160)(H,130,162)(H,131,168)(H,132,161)(H,133,169)(H,143,144)(H,145,146)(H,147,148)(H,149,150)(H,151,152)(H,153,154)/t56-,57+,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,92-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214192
(CHEMBL428833)Show SMILES CSCC[C@H](NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C110H146N24O38S/c1-53(2)39-67(120-101(163)75(47-87(147)148)129-104(166)77(49-89(151)152)127-96(158)68(40-58-19-10-8-11-20-58)121-103(165)76(48-88(149)150)128-98(160)71(43-61-50-113-64-24-15-14-23-63(61)64)124-94(156)66(34-38-173-7)117-57(6)137)95(157)125-72(44-82(111)139)99(161)123-70(41-59-21-12-9-13-22-59)105(167)131-90(56(5)136)107(169)114-51-83(140)115-55(4)108(170)134-37-18-27-81(134)110(172)133-36-17-26-80(133)106(168)116-54(3)92(154)119-73(45-85(143)144)100(162)118-65(32-33-84(141)142)93(155)126-74(46-86(145)146)102(164)122-69(42-60-28-30-62(138)31-29-60)97(159)130-78(52-135)109(171)132-35-16-25-79(132)91(112)153/h8-15,19-24,28-31,50,53-56,65-81,90,113,135-136,138H,16-18,25-27,32-49,51-52H2,1-7H3,(H2,111,139)(H2,112,153)(H,114,169)(H,115,140)(H,116,168)(H,117,137)(H,118,162)(H,119,154)(H,120,163)(H,121,165)(H,122,164)(H,123,161)(H,124,156)(H,125,157)(H,126,155)(H,127,158)(H,128,160)(H,129,166)(H,130,159)(H,131,167)(H,141,142)(H,143,144)(H,145,146)(H,147,148)(H,149,150)(H,151,152)/t54-,55-,56+,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,90-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214193
(CHEMBL410889)Show SMILES CSCC[C@H](NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C112H150N24O37S2/c1-55(2)42-70(123-103(164)78(50-89(148)149)132-106(167)80(52-91(152)153)130-99(160)72(43-60-20-11-9-12-21-60)125-105(166)79(51-90(150)151)131-100(161)74(46-63-53-115-66-25-16-15-24-65(63)66)127-96(157)68(35-40-174-7)119-59(6)138)98(159)128-75(47-84(113)140)101(162)126-73(44-61-22-13-10-14-23-61)107(168)133-92(58(5)137)109(170)116-54-85(141)120-69(36-41-175-8)111(172)136-39-19-28-83(136)112(173)135-38-18-27-82(135)108(169)117-56(3)94(155)122-76(48-87(144)145)102(163)121-67(33-34-86(142)143)95(156)129-77(49-88(146)147)104(165)124-71(45-62-29-31-64(139)32-30-62)97(158)118-57(4)110(171)134-37-17-26-81(134)93(114)154/h9-16,20-25,29-32,53,55-58,67-83,92,115,137,139H,17-19,26-28,33-52,54H2,1-8H3,(H2,113,140)(H2,114,154)(H,116,170)(H,117,169)(H,118,158)(H,119,138)(H,120,141)(H,121,163)(H,122,155)(H,123,164)(H,124,165)(H,125,166)(H,126,162)(H,127,157)(H,128,159)(H,129,156)(H,130,160)(H,131,161)(H,132,167)(H,133,168)(H,142,143)(H,144,145)(H,146,147)(H,148,149)(H,150,151)(H,152,153)/t56-,57-,58+,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,92-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214184
(CHEMBL438420)Show SMILES CSCC[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(C)=O)[C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C110H146N24O38S/c1-53(2)39-67(121-101(163)75(47-87(147)148)129-104(166)77(49-89(151)152)127-96(158)68(40-58-19-10-8-11-20-58)122-103(165)76(48-88(149)150)128-98(160)71(119-92(154)54(3)115-57(6)137)43-61-50-113-64-24-15-14-23-63(61)64)95(157)125-72(44-82(111)139)99(161)124-70(41-59-21-12-9-13-22-59)105(167)131-90(56(5)136)107(169)114-51-83(140)117-66(34-38-173-7)108(170)134-37-18-27-81(134)110(172)133-36-17-26-80(133)106(168)116-55(4)93(155)120-73(45-85(143)144)100(162)118-65(32-33-84(141)142)94(156)126-74(46-86(145)146)102(164)123-69(42-60-28-30-62(138)31-29-60)97(159)130-78(52-135)109(171)132-35-16-25-79(132)91(112)153/h8-15,19-24,28-31,50,53-56,65-81,90,113,135-136,138H,16-18,25-27,32-49,51-52H2,1-7H3,(H2,111,139)(H2,112,153)(H,114,169)(H,115,137)(H,116,168)(H,117,140)(H,118,162)(H,119,154)(H,120,155)(H,121,163)(H,122,165)(H,123,164)(H,124,161)(H,125,157)(H,126,156)(H,127,158)(H,128,160)(H,129,166)(H,130,159)(H,131,167)(H,141,142)(H,143,144)(H,145,146)(H,147,148)(H,149,150)(H,151,152)/t54-,55-,56+,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,90-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214187
(CHEMBL415828)Show SMILES CSCC[C@H](NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C110H148N24O38S2/c1-53(2)39-68(121-102(164)76(47-87(147)148)130-105(167)78(49-89(151)152)128-97(159)69(40-58-19-11-9-12-20-58)122-104(166)77(48-88(149)150)129-99(161)72(43-61-50-113-64-24-16-15-23-63(61)64)125-95(157)66(33-37-173-7)117-57(6)137)96(158)126-73(44-82(111)139)100(162)124-71(41-59-21-13-10-14-22-59)106(168)132-90(56(5)136)108(170)114-51-83(140)118-67(34-38-174-8)109(171)134-36-18-26-81(134)107(169)116-54(3)92(154)115-55(4)93(155)120-74(45-85(143)144)101(163)119-65(31-32-84(141)142)94(156)127-75(46-86(145)146)103(165)123-70(42-60-27-29-62(138)30-28-60)98(160)131-79(52-135)110(172)133-35-17-25-80(133)91(112)153/h9-16,19-24,27-30,50,53-56,65-81,90,113,135-136,138H,17-18,25-26,31-49,51-52H2,1-8H3,(H2,111,139)(H2,112,153)(H,114,170)(H,115,154)(H,116,169)(H,117,137)(H,118,140)(H,119,163)(H,120,155)(H,121,164)(H,122,166)(H,123,165)(H,124,162)(H,125,157)(H,126,158)(H,127,156)(H,128,159)(H,129,161)(H,130,167)(H,131,160)(H,132,168)(H,141,142)(H,143,144)(H,145,146)(H,147,148)(H,149,150)(H,151,152)/t54-,55-,56+,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,90-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214173
(CHEMBL442313)Show SMILES CSCC[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(C)=O)[C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C107H141N23O37S/c1-52(2)38-65(117-98(158)73(46-85(143)144)125-101(161)75(48-87(147)148)123-93(153)66(39-56-18-9-7-10-19-56)118-100(160)74(47-86(145)146)124-95(155)69(113-55(5)133)42-59-49-110-62-23-14-13-22-61(59)62)92(152)121-70(43-80(108)135)96(156)120-68(40-57-20-11-8-12-21-57)102(162)127-88(54(4)132)104(164)111-50-81(136)114-64(33-37-168-6)105(165)130-36-17-26-79(130)107(167)129-35-16-25-78(129)103(163)112-53(3)90(150)116-71(44-83(139)140)97(157)115-63(31-32-82(137)138)91(151)122-72(45-84(141)142)99(159)119-67(41-58-27-29-60(134)30-28-58)94(154)126-76(51-131)106(166)128-34-15-24-77(128)89(109)149/h7-14,18-23,27-30,49,52-54,63-79,88,110,131-132,134H,15-17,24-26,31-48,50-51H2,1-6H3,(H2,108,135)(H2,109,149)(H,111,164)(H,112,163)(H,113,133)(H,114,136)(H,115,157)(H,116,150)(H,117,158)(H,118,160)(H,119,159)(H,120,156)(H,121,152)(H,122,151)(H,123,153)(H,124,155)(H,125,161)(H,126,154)(H,127,162)(H,137,138)(H,139,140)(H,141,142)(H,143,144)(H,145,146)(H,147,148)/t53-,54+,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,88-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214156
(CHEMBL414166)Show SMILES CSCC[C@H](NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C111H150N24O36S2/c1-55(2)42-70(123-103(163)78(50-89(148)149)130-105(165)79(51-90(150)151)129-99(159)71(43-60-20-11-9-12-21-60)121-93(153)56(3)116-97(157)74(46-63-52-114-66-25-16-15-24-65(63)66)126-96(156)68(35-40-172-7)118-59(6)138)98(158)127-75(47-84(112)140)101(161)125-73(44-61-22-13-10-14-23-61)106(166)132-91(58(5)137)108(168)115-53-85(141)119-69(36-41-173-8)109(169)135-39-19-28-83(135)111(171)134-38-18-27-82(134)107(167)117-57(4)94(154)122-76(48-87(144)145)102(162)120-67(33-34-86(142)143)95(155)128-77(49-88(146)147)104(164)124-72(45-62-29-31-64(139)32-30-62)100(160)131-80(54-136)110(170)133-37-17-26-81(133)92(113)152/h9-16,20-25,29-32,52,55-58,67-83,91,114,136-137,139H,17-19,26-28,33-51,53-54H2,1-8H3,(H2,112,140)(H2,113,152)(H,115,168)(H,116,157)(H,117,167)(H,118,138)(H,119,141)(H,120,162)(H,121,153)(H,122,154)(H,123,163)(H,124,164)(H,125,161)(H,126,156)(H,127,158)(H,128,155)(H,129,159)(H,130,165)(H,131,160)(H,132,166)(H,142,143)(H,144,145)(H,146,147)(H,148,149)(H,150,151)/t56-,57-,58+,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,91-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 2.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214190
(CHEMBL266910)Show SMILES CSCC[C@H](NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C110H148N24O36S2/c1-54(2)40-68(121-102(162)76(48-87(145)146)129-104(164)78(50-89(149)150)127-97(157)69(41-59-20-11-9-12-21-59)122-103(163)77(49-88(147)148)128-99(159)72(44-62-51-113-65-25-16-15-24-64(62)65)125-94(154)66(33-38-171-7)117-58(6)137)96(156)126-73(45-83(111)139)100(160)124-71(42-60-22-13-10-14-23-60)105(165)131-90(57(5)136)107(167)114-52-84(140)118-67(34-39-172-8)108(168)134-37-19-28-82(134)110(170)133-36-18-27-81(133)106(166)116-56(4)93(153)119-74(46-85(141)142)95(155)115-55(3)92(152)120-75(47-86(143)144)101(161)123-70(43-61-29-31-63(138)32-30-61)98(158)130-79(53-135)109(169)132-35-17-26-80(132)91(112)151/h9-16,20-25,29-32,51,54-57,66-82,90,113,135-136,138H,17-19,26-28,33-50,52-53H2,1-8H3,(H2,111,139)(H2,112,151)(H,114,167)(H,115,155)(H,116,166)(H,117,137)(H,118,140)(H,119,153)(H,120,152)(H,121,162)(H,122,163)(H,123,161)(H,124,160)(H,125,154)(H,126,156)(H,127,157)(H,128,159)(H,129,164)(H,130,158)(H,131,165)(H,141,142)(H,143,144)(H,145,146)(H,147,148)(H,149,150)/t55-,56-,57+,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,90-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214152
(CHEMBL439107)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(N)=O Show InChI InChI=1S/C100H142N24O34S2/c1-10-48(4)80(121-94(152)65(39-74(103)131)115-95(153)70(46-125)120-84(142)58(29-32-159-8)107-51(7)128)98(156)123-82(50(6)127)99(157)119-69(43-79(139)140)100(158)124-31-19-26-71(124)96(154)109-57(27-28-72(101)129)83(141)108-59(30-33-160-9)85(143)113-63(37-54-44-105-56-25-18-17-24-55(54)56)88(146)117-67(41-77(135)136)91(149)111-61(35-52-20-13-11-14-21-52)87(145)116-68(42-78(137)138)92(150)118-66(40-76(133)134)90(148)110-60(34-47(2)3)86(144)114-64(38-73(102)130)89(147)112-62(36-53-22-15-12-16-23-53)93(151)122-81(49(5)126)97(155)106-45-75(104)132/h11-18,20-25,44,47-50,57-71,80-82,105,125-127H,10,19,26-43,45-46H2,1-9H3,(H2,101,129)(H2,102,130)(H2,103,131)(H2,104,132)(H,106,155)(H,107,128)(H,108,141)(H,109,154)(H,110,148)(H,111,149)(H,112,147)(H,113,143)(H,114,144)(H,115,153)(H,116,145)(H,117,146)(H,118,150)(H,119,157)(H,120,142)(H,121,152)(H,122,151)(H,123,156)(H,133,134)(H,135,136)(H,137,138)(H,139,140)/t48-,49+,50+,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,80-,81-,82-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214160
(CHEMBL436775)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(C)=O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(N)=O Show InChI InChI=1S/C75H111N17O16/c1-12-43(9)63(92-72(105)56(35-48-37-79-51-29-21-20-28-49(48)51)83-59(96)38-80-67(100)57(36-58(77)95)89-73(106)62(42(7)8)82-45(11)94)74(107)87-54(33-46-24-16-14-17-25-46)66(99)81-39-60(97)90-64(44(10)93)75(108)88-55(34-47-26-18-15-19-27-47)71(104)86-53(32-40(3)4)70(103)84-50(13-2)68(101)85-52(30-22-23-31-76)69(102)91-61(41(5)6)65(78)98/h14-21,24-29,37,40-44,50,52-57,61-64,79,93H,12-13,22-23,30-36,38-39,76H2,1-11H3,(H2,77,95)(H2,78,98)(H,80,100)(H,81,99)(H,82,94)(H,83,96)(H,84,103)(H,85,101)(H,86,104)(H,87,107)(H,88,108)(H,89,106)(H,90,97)(H,91,102)(H,92,105)/t43-,44+,50+,52-,53-,54-,55-,56-,57-,61-,62-,63-,64-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214178
(CHEMBL439291)Show SMILES CSCC[C@H](NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C111H150N24O36S2/c1-55(2)42-70(123-103(163)77(49-88(146)147)122-93(153)56(3)116-97(157)71(43-60-20-11-9-12-21-60)124-105(165)79(51-90(150)151)130-100(160)74(46-63-52-114-66-25-16-15-24-65(63)66)127-96(156)68(35-40-172-7)118-59(6)138)98(158)128-75(47-84(112)140)101(161)126-73(44-61-22-13-10-14-23-61)106(166)132-91(58(5)137)108(168)115-53-85(141)119-69(36-41-173-8)109(169)135-39-19-28-83(135)111(171)134-38-18-27-82(134)107(167)117-57(4)94(154)121-76(48-87(144)145)102(162)120-67(33-34-86(142)143)95(155)129-78(50-89(148)149)104(164)125-72(45-62-29-31-64(139)32-30-62)99(159)131-80(54-136)110(170)133-37-17-26-81(133)92(113)152/h9-16,20-25,29-32,52,55-58,67-83,91,114,136-137,139H,17-19,26-28,33-51,53-54H2,1-8H3,(H2,112,140)(H2,113,152)(H,115,168)(H,116,157)(H,117,167)(H,118,138)(H,119,141)(H,120,162)(H,121,154)(H,122,153)(H,123,163)(H,124,165)(H,125,164)(H,126,161)(H,127,156)(H,128,158)(H,129,155)(H,130,160)(H,131,159)(H,132,166)(H,142,143)(H,144,145)(H,146,147)(H,148,149)(H,150,151)/t56-,57-,58+,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,91-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214154
(CHEMBL443593)Show SMILES CSCC[C@H](NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C111H150N24O36S2/c1-55(2)42-70(123-103(163)77(49-88(146)147)130-105(165)79(51-90(150)151)128-98(158)72(43-60-20-11-9-12-21-60)124-104(164)78(50-89(148)149)129-100(160)74(46-63-52-114-66-25-16-15-24-65(63)66)126-96(156)68(35-40-172-7)118-59(6)138)97(157)127-75(47-84(112)140)101(161)125-73(44-61-22-13-10-14-23-61)106(166)132-91(58(5)137)108(168)115-53-85(141)119-69(36-41-173-8)109(169)135-39-19-28-83(135)111(171)134-38-18-27-82(134)107(167)117-57(4)94(154)122-76(48-87(144)145)102(162)120-67(33-34-86(142)143)95(155)116-56(3)93(153)121-71(45-62-29-31-64(139)32-30-62)99(159)131-80(54-136)110(170)133-37-17-26-81(133)92(113)152/h9-16,20-25,29-32,52,55-58,67-83,91,114,136-137,139H,17-19,26-28,33-51,53-54H2,1-8H3,(H2,112,140)(H2,113,152)(H,115,168)(H,116,155)(H,117,167)(H,118,138)(H,119,141)(H,120,162)(H,121,153)(H,122,154)(H,123,163)(H,124,164)(H,125,161)(H,126,156)(H,127,157)(H,128,158)(H,129,160)(H,130,165)(H,131,159)(H,132,166)(H,142,143)(H,144,145)(H,146,147)(H,148,149)(H,150,151)/t56-,57-,58+,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,91-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 4.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214159
(CHEMBL415385)Show SMILES CSCC[C@H](NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C111H149N23O37S2/c1-55(2)42-70(122-102(162)77(49-88(146)147)129-105(165)79(51-90(150)151)127-98(158)71(43-60-20-11-9-12-21-60)123-104(164)78(50-89(148)149)128-100(160)74(46-63-52-113-66-25-16-15-24-65(63)66)125-96(156)68(35-40-172-7)117-59(6)137)97(157)115-56(3)93(153)120-73(44-61-22-13-10-14-23-61)106(166)131-91(58(5)136)108(168)114-53-84(139)118-69(36-41-173-8)109(169)134-39-19-28-83(134)111(171)133-38-18-27-82(133)107(167)116-57(4)94(154)121-75(47-86(142)143)101(161)119-67(33-34-85(140)141)95(155)126-76(48-87(144)145)103(163)124-72(45-62-29-31-64(138)32-30-62)99(159)130-80(54-135)110(170)132-37-17-26-81(132)92(112)152/h9-16,20-25,29-32,52,55-58,67-83,91,113,135-136,138H,17-19,26-28,33-51,53-54H2,1-8H3,(H2,112,152)(H,114,168)(H,115,157)(H,116,167)(H,117,137)(H,118,139)(H,119,161)(H,120,153)(H,121,154)(H,122,162)(H,123,164)(H,124,163)(H,125,156)(H,126,155)(H,127,158)(H,128,160)(H,129,165)(H,130,159)(H,131,166)(H,140,141)(H,142,143)(H,144,145)(H,146,147)(H,148,149)(H,150,151)/t56-,57-,58+,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,91-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 4.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214162
(CHEMBL410689)Show SMILES CSCC[C@H](NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C106H146N24O38S2/c1-50(2)37-64(118-99(161)73(46-85(147)148)125-98(160)71(44-83(143)144)117-88(150)51(3)111-92(154)69(42-81(139)140)124-95(157)67(40-57-47-109-60-20-13-12-19-59(57)60)121-91(153)62(30-35-169-7)113-54(6)133)93(155)122-68(41-78(107)135)96(158)120-66(38-55-17-10-9-11-18-55)101(163)127-86(53(5)132)103(165)110-48-79(136)114-63(31-36-170-8)104(166)130-34-16-23-77(130)106(168)129-33-15-22-76(129)102(164)112-52(4)89(151)116-70(43-82(141)142)97(159)115-61(28-29-80(137)138)90(152)123-72(45-84(145)146)100(162)119-65(39-56-24-26-58(134)27-25-56)94(156)126-74(49-131)105(167)128-32-14-21-75(128)87(108)149/h9-13,17-20,24-27,47,50-53,61-77,86,109,131-132,134H,14-16,21-23,28-46,48-49H2,1-8H3,(H2,107,135)(H2,108,149)(H,110,165)(H,111,154)(H,112,164)(H,113,133)(H,114,136)(H,115,159)(H,116,151)(H,117,150)(H,118,161)(H,119,162)(H,120,158)(H,121,153)(H,122,155)(H,123,152)(H,124,157)(H,125,160)(H,126,156)(H,127,163)(H,137,138)(H,139,140)(H,141,142)(H,143,144)(H,145,146)(H,147,148)/t51-,52-,53+,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,86-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 4.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214180
(CHEMBL415612)Show SMILES CSCC[C@H](NC(C)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C104H145N23O38S2/c1-50(2)38-62(115-96(157)70(46-82(142)143)122-98(159)71(47-83(144)145)121-91(152)63(39-55-18-11-9-12-19-55)116-95(156)68(44-80(138)139)114-86(147)51(3)108-88(149)60(31-36-166-7)110-54(6)130)90(151)119-66(42-76(105)132)93(154)118-65(40-56-20-13-10-14-21-56)99(160)124-84(53(5)129)101(162)107-48-77(133)111-61(32-37-167-8)102(163)127-35-17-24-75(127)104(165)126-34-16-23-74(126)100(161)109-52(4)87(148)113-67(43-79(136)137)94(155)112-59(29-30-78(134)135)89(150)120-69(45-81(140)141)97(158)117-64(41-57-25-27-58(131)28-26-57)92(153)123-72(49-128)103(164)125-33-15-22-73(125)85(106)146/h9-14,18-21,25-28,50-53,59-75,84,128-129,131H,15-17,22-24,29-49H2,1-8H3,(H2,105,132)(H2,106,146)(H,107,162)(H,108,149)(H,109,161)(H,110,130)(H,111,133)(H,112,155)(H,113,148)(H,114,147)(H,115,157)(H,116,156)(H,117,158)(H,118,154)(H,119,151)(H,120,150)(H,121,152)(H,122,159)(H,123,153)(H,124,160)(H,134,135)(H,136,137)(H,138,139)(H,140,141)(H,142,143)(H,144,145)/t51-,52-,53+,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,84-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 5.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214189
(CHEMBL266999)Show SMILES CSCC[C@H](NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C111H150N24O36S2/c1-55(2)42-70(121-102(162)77(49-88(146)147)130-105(165)79(51-90(150)151)128-98(158)71(43-60-20-11-9-12-21-60)122-104(164)78(50-89(148)149)129-100(160)74(46-63-52-114-66-25-16-15-24-65(63)66)125-96(156)68(35-40-172-7)118-59(6)138)97(157)126-75(47-84(112)140)101(161)124-73(44-61-22-13-10-14-23-61)106(166)132-91(58(5)137)108(168)115-53-85(141)119-69(36-41-173-8)109(169)135-39-19-28-83(135)111(171)134-38-18-27-82(134)107(167)117-56(3)93(153)116-57(4)94(154)120-67(33-34-86(142)143)95(155)127-76(48-87(144)145)103(163)123-72(45-62-29-31-64(139)32-30-62)99(159)131-80(54-136)110(170)133-37-17-26-81(133)92(113)152/h9-16,20-25,29-32,52,55-58,67-83,91,114,136-137,139H,17-19,26-28,33-51,53-54H2,1-8H3,(H2,112,140)(H2,113,152)(H,115,168)(H,116,153)(H,117,167)(H,118,138)(H,119,141)(H,120,154)(H,121,162)(H,122,164)(H,123,163)(H,124,161)(H,125,156)(H,126,157)(H,127,155)(H,128,158)(H,129,160)(H,130,165)(H,131,159)(H,132,166)(H,142,143)(H,144,145)(H,146,147)(H,148,149)(H,150,151)/t56-,57-,58+,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,91-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 5.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214179
(CHEMBL411496)Show SMILES CSCC[C@H](NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C109H144N24O38S2/c1-53(114-95(157)72(45-84(142)143)126-103(165)76(49-88(150)151)127-96(158)67(40-57-18-9-7-10-19-57)121-102(164)75(48-87(148)149)128-98(160)70(43-60-50-112-63-23-14-13-22-62(60)63)124-94(156)65(33-38-172-5)116-56(4)136)91(153)119-71(44-81(110)138)99(161)123-69(41-58-20-11-8-12-21-58)104(166)130-89(55(3)135)106(168)113-51-82(139)117-66(34-39-173-6)107(169)133-37-17-26-80(133)109(171)132-36-16-25-79(132)105(167)115-54(2)92(154)120-73(46-85(144)145)100(162)118-64(31-32-83(140)141)93(155)125-74(47-86(146)147)101(163)122-68(42-59-27-29-61(137)30-28-59)97(159)129-77(52-134)108(170)131-35-15-24-78(131)90(111)152/h7-14,18-23,27-30,50,53-55,64-80,89,112,134-135,137H,15-17,24-26,31-49,51-52H2,1-6H3,(H2,110,138)(H2,111,152)(H,113,168)(H,114,157)(H,115,167)(H,116,136)(H,117,139)(H,118,162)(H,119,153)(H,120,154)(H,121,164)(H,122,163)(H,123,161)(H,124,156)(H,125,155)(H,126,165)(H,127,158)(H,128,160)(H,129,159)(H,130,166)(H,140,141)(H,142,143)(H,144,145)(H,146,147)(H,148,149)(H,150,151)/t53-,54-,55+,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,89-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 6.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214163
(CHEMBL412745)Show SMILES CSCC[C@H](NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C111H150N24O36S2/c1-55(2)42-70(121-93(153)56(3)116-97(157)76(48-87(144)145)129-99(159)71(43-60-20-11-9-12-21-60)123-105(165)79(51-90(150)151)130-101(161)74(46-63-52-114-66-25-16-15-24-65(63)66)126-96(156)68(35-40-172-7)118-59(6)138)98(158)127-75(47-84(112)140)102(162)125-73(44-61-22-13-10-14-23-61)106(166)132-91(58(5)137)108(168)115-53-85(141)119-69(36-41-173-8)109(169)135-39-19-28-83(135)111(171)134-38-18-27-82(134)107(167)117-57(4)94(154)122-77(49-88(146)147)103(163)120-67(33-34-86(142)143)95(155)128-78(50-89(148)149)104(164)124-72(45-62-29-31-64(139)32-30-62)100(160)131-80(54-136)110(170)133-37-17-26-81(133)92(113)152/h9-16,20-25,29-32,52,55-58,67-83,91,114,136-137,139H,17-19,26-28,33-51,53-54H2,1-8H3,(H2,112,140)(H2,113,152)(H,115,168)(H,116,157)(H,117,167)(H,118,138)(H,119,141)(H,120,163)(H,121,153)(H,122,154)(H,123,165)(H,124,164)(H,125,162)(H,126,156)(H,127,158)(H,128,155)(H,129,159)(H,130,161)(H,131,160)(H,132,166)(H,142,143)(H,144,145)(H,146,147)(H,148,149)(H,150,151)/t56-,57-,58+,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,91-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 6.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214186
(CHEMBL408320)Show SMILES CSCC[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(C)=O)[C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C96H131N21O36S/c1-46(2)34-56(105-88(145)64(42-76(132)133)112-90(147)65(43-77(134)135)111-83(140)57(35-50-16-9-7-10-17-50)106-86(143)61(39-73(126)127)101-49(5)120)82(139)109-60(38-70(97)122)85(142)108-59(36-51-18-11-8-12-19-51)91(148)114-78(48(4)119)93(150)99-44-71(123)102-55(29-33-154-6)94(151)117-32-15-22-69(117)96(153)116-31-14-21-68(116)92(149)100-47(3)80(137)104-62(40-74(128)129)87(144)103-54(27-28-72(124)125)81(138)110-63(41-75(130)131)89(146)107-58(37-52-23-25-53(121)26-24-52)84(141)113-66(45-118)95(152)115-30-13-20-67(115)79(98)136/h7-12,16-19,23-26,46-48,54-69,78,118-119,121H,13-15,20-22,27-45H2,1-6H3,(H2,97,122)(H2,98,136)(H,99,150)(H,100,149)(H,101,120)(H,102,123)(H,103,144)(H,104,137)(H,105,145)(H,106,143)(H,107,146)(H,108,142)(H,109,139)(H,110,138)(H,111,140)(H,112,147)(H,113,141)(H,114,148)(H,124,125)(H,126,127)(H,128,129)(H,130,131)(H,132,133)(H,134,135)/t47-,48+,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,78-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 6.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214183
(CHEMBL264498)Show SMILES CSCC[C@H](NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C106H146N24O38S2/c1-50(2)37-64(117-98(160)71(44-83(143)144)125-101(163)73(46-85(147)148)123-94(156)65(38-55-17-10-9-11-18-55)118-100(162)72(45-84(145)146)124-96(158)67(40-57-47-109-60-20-13-12-19-59(57)60)120-91(153)62(30-35-169-7)113-54(6)133)93(155)121-68(41-78(107)135)92(154)111-52(4)89(151)127-86(53(5)132)103(165)110-48-79(136)114-63(31-36-170-8)104(166)130-34-16-23-77(130)106(168)129-33-15-22-76(129)102(164)112-51(3)88(150)116-69(42-81(139)140)97(159)115-61(28-29-80(137)138)90(152)122-70(43-82(141)142)99(161)119-66(39-56-24-26-58(134)27-25-56)95(157)126-74(49-131)105(167)128-32-14-21-75(128)87(108)149/h9-13,17-20,24-27,47,50-53,61-77,86,109,131-132,134H,14-16,21-23,28-46,48-49H2,1-8H3,(H2,107,135)(H2,108,149)(H,110,165)(H,111,154)(H,112,164)(H,113,133)(H,114,136)(H,115,159)(H,116,150)(H,117,160)(H,118,162)(H,119,161)(H,120,153)(H,121,155)(H,122,152)(H,123,156)(H,124,158)(H,125,163)(H,126,157)(H,127,151)(H,137,138)(H,139,140)(H,141,142)(H,143,144)(H,145,146)(H,147,148)/t51-,52-,53+,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,86-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 1.07E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214151
(CHEMBL414538)Show SMILES CSCC[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)[C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C92H126N20O33S/c1-45(2)34-55(101-84(137)62(41-73(125)126)107-86(139)63(42-74(127)128)106-80(133)56(97-48(5)115)35-49-16-9-7-10-17-49)79(132)104-59(38-68(93)117)82(135)103-58(36-50-18-11-8-12-19-50)87(140)109-75(47(4)114)89(142)95-43-69(118)98-54(29-33-146-6)90(143)112-32-15-22-67(112)92(145)111-31-14-21-66(111)88(141)96-46(3)77(130)100-60(39-71(121)122)83(136)99-53(27-28-70(119)120)78(131)105-61(40-72(123)124)85(138)102-57(37-51-23-25-52(116)26-24-51)81(134)108-64(44-113)91(144)110-30-13-20-65(110)76(94)129/h7-12,16-19,23-26,45-47,53-67,75,113-114,116H,13-15,20-22,27-44H2,1-6H3,(H2,93,117)(H2,94,129)(H,95,142)(H,96,141)(H,97,115)(H,98,118)(H,99,136)(H,100,130)(H,101,137)(H,102,138)(H,103,135)(H,104,132)(H,105,131)(H,106,133)(H,107,139)(H,108,134)(H,109,140)(H,119,120)(H,121,122)(H,123,124)(H,125,126)(H,127,128)/t46-,47+,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,75-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 1.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214191
(CHEMBL269493)Show SMILES CSCC[C@H](NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(N)=O Show InChI InChI=1S/C110H148N24O38S2/c1-53(2)39-68(121-101(163)76(47-87(147)148)130-104(166)78(49-89(151)152)128-96(158)69(40-58-19-11-9-12-20-58)122-103(165)77(48-88(149)150)129-98(160)72(43-61-50-113-64-24-16-15-23-63(61)64)125-94(156)66(33-37-173-7)117-57(6)137)95(157)126-73(44-82(111)139)99(161)124-71(41-59-21-13-10-14-22-59)105(167)132-90(56(5)136)108(170)114-51-83(140)118-67(34-38-174-8)109(171)134-36-18-26-81(134)110(172)133-35-17-25-80(133)107(169)116-55(4)92(154)120-74(45-85(143)144)100(162)119-65(31-32-84(141)142)93(155)127-75(46-86(145)146)102(164)123-70(42-60-27-29-62(138)30-28-60)97(159)131-79(52-135)106(168)115-54(3)91(112)153/h9-16,19-24,27-30,50,53-56,65-81,90,113,135-136,138H,17-18,25-26,31-49,51-52H2,1-8H3,(H2,111,139)(H2,112,153)(H,114,170)(H,115,168)(H,116,169)(H,117,137)(H,118,140)(H,119,162)(H,120,154)(H,121,163)(H,122,165)(H,123,164)(H,124,161)(H,125,156)(H,126,157)(H,127,155)(H,128,158)(H,129,160)(H,130,166)(H,131,159)(H,132,167)(H,141,142)(H,143,144)(H,145,146)(H,147,148)(H,149,150)(H,151,152)/t54-,55-,56+,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,90-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 1.55E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214174
(CHEMBL411434)Show SMILES [H][C@](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(O)=O)NC(C)=O)([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@@]1([H])C(N)=O Show InChI InChI=1S/C83H117N19O32S/c1-39(2)29-48(92-76(127)55(36-66(117)118)97-74(125)52(33-63(111)112)88-42(5)105)71(122)95-51(32-60(84)107)73(124)94-50(30-43-13-8-7-9-14-43)78(129)99-67(41(4)104)80(131)86-37-61(108)89-47(24-28-135-6)81(132)102-27-12-17-59(102)83(134)101-26-11-16-58(101)79(130)87-40(3)69(120)91-53(34-64(113)114)75(126)90-46(22-23-62(109)110)70(121)96-54(35-65(115)116)77(128)93-49(31-44-18-20-45(106)21-19-44)72(123)98-56(38-103)82(133)100-25-10-15-57(100)68(85)119/h7-9,13-14,18-21,39-41,46-59,67,103-104,106H,10-12,15-17,22-38H2,1-6H3,(H2,84,107)(H2,85,119)(H,86,131)(H,87,130)(H,88,105)(H,89,108)(H,90,126)(H,91,120)(H,92,127)(H,93,128)(H,94,124)(H,95,122)(H,96,121)(H,97,125)(H,98,123)(H,99,129)(H,109,110)(H,111,112)(H,113,114)(H,115,116)(H,117,118)/t40-,41+,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,67-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 1.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214150
(CHEMBL409378)Show SMILES CSCC[C@H](NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C106H146N24O37S2/c1-51(2)38-64(117-98(159)71(45-83(142)143)125-100(161)73(47-85(146)147)123-94(155)65(39-56-20-11-9-12-21-56)118-99(160)72(46-84(144)145)124-95(156)67(41-58-48-109-60-25-16-15-24-59(58)60)120-91(152)62(31-36-168-7)113-55(6)133)93(154)121-68(42-78(107)134)96(157)119-66(40-57-22-13-10-14-23-57)101(162)127-86(54(5)132)103(164)110-49-79(135)114-63(32-37-169-8)104(165)130-35-19-28-77(130)106(167)129-34-18-27-76(129)102(163)112-53(4)88(149)116-70(44-82(140)141)97(158)115-61(29-30-80(136)137)90(151)122-69(43-81(138)139)92(153)111-52(3)89(150)126-74(50-131)105(166)128-33-17-26-75(128)87(108)148/h9-16,20-25,48,51-54,61-77,86,109,131-132H,17-19,26-47,49-50H2,1-8H3,(H2,107,134)(H2,108,148)(H,110,164)(H,111,153)(H,112,163)(H,113,133)(H,114,135)(H,115,158)(H,116,149)(H,117,159)(H,118,160)(H,119,157)(H,120,152)(H,121,154)(H,122,151)(H,123,155)(H,124,156)(H,125,161)(H,126,150)(H,127,162)(H,136,137)(H,138,139)(H,140,141)(H,142,143)(H,144,145)(H,146,147)/t52-,53-,54+,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,86-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 2.65E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214181
(CHEMBL437667)Show SMILES CSCC[C@H](NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C110H148N24O38S2/c1-53(2)39-68(121-102(164)76(47-87(147)148)130-105(167)78(49-89(151)152)128-97(159)69(40-58-19-11-9-12-20-58)122-104(166)77(48-88(149)150)129-99(161)72(43-61-50-113-64-24-16-15-23-63(61)64)125-95(157)66(33-37-173-7)117-57(6)137)96(158)126-73(44-82(111)139)100(162)124-71(41-59-21-13-10-14-22-59)106(168)132-90(56(5)136)108(170)114-51-83(140)118-67(34-38-174-8)93(155)116-55(4)109(171)134-36-18-26-81(134)107(169)115-54(3)92(154)120-74(45-85(143)144)101(163)119-65(31-32-84(141)142)94(156)127-75(46-86(145)146)103(165)123-70(42-60-27-29-62(138)30-28-60)98(160)131-79(52-135)110(172)133-35-17-25-80(133)91(112)153/h9-16,19-24,27-30,50,53-56,65-81,90,113,135-136,138H,17-18,25-26,31-49,51-52H2,1-8H3,(H2,111,139)(H2,112,153)(H,114,170)(H,115,169)(H,116,155)(H,117,137)(H,118,140)(H,119,163)(H,120,154)(H,121,164)(H,122,166)(H,123,165)(H,124,162)(H,125,157)(H,126,158)(H,127,156)(H,128,159)(H,129,161)(H,130,167)(H,131,160)(H,132,168)(H,141,142)(H,143,144)(H,145,146)(H,147,148)(H,149,150)(H,151,152)/t54-,55-,56+,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,90-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 4.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50213963
(CHEMBL410977)Show SMILES CSCC[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(C)=O)[C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C79H112N18O29S/c1-38(2)29-47(88-71(118)51(33-61(106)107)84-41(5)100)68(115)91-50(32-58(80)102)70(117)90-49(30-42-13-8-7-9-14-42)74(121)94-64(40(4)99)76(123)82-36-59(103)85-46(24-28-127-6)77(124)97-27-12-17-57(97)79(126)96-26-11-16-56(96)75(122)83-39(3)66(113)87-52(34-62(108)109)72(119)86-45(22-23-60(104)105)67(114)92-53(35-63(110)111)73(120)89-48(31-43-18-20-44(101)21-19-43)69(116)93-54(37-98)78(125)95-25-10-15-55(95)65(81)112/h7-9,13-14,18-21,38-40,45-57,64,98-99,101H,10-12,15-17,22-37H2,1-6H3,(H2,80,102)(H2,81,112)(H,82,123)(H,83,122)(H,84,100)(H,85,103)(H,86,119)(H,87,113)(H,88,118)(H,89,120)(H,90,117)(H,91,115)(H,92,114)(H,93,116)(H,94,121)(H,104,105)(H,106,107)(H,108,109)(H,110,111)/t39-,40+,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,64-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 7.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214176
(CHEMBL262779)Show SMILES CSCC[C@H](NC(=O)CNC(C)=O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C52H74N12O20S/c1-26(55-49(81)37-8-5-18-63(37)52(84)38-9-6-19-64(38)50(82)31(16-20-85-3)56-39(68)24-54-27(2)66)44(76)58-33(22-41(71)72)47(79)57-30(14-15-40(69)70)45(77)60-34(23-42(73)74)48(80)59-32(21-28-10-12-29(67)13-11-28)46(78)61-35(25-65)51(83)62-17-4-7-36(62)43(53)75/h10-13,26,30-38,65,67H,4-9,14-25H2,1-3H3,(H2,53,75)(H,54,66)(H,55,81)(H,56,68)(H,57,79)(H,58,76)(H,59,80)(H,60,77)(H,61,78)(H,69,70)(H,71,72)(H,73,74)/t26-,30-,31-,32-,33-,34-,35-,36-,37-,38-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 8.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214177
(CHEMBL409189)Show SMILES CSCC[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(C)=O)[C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C65H90N14O23S/c1-33(68-61(98)47-14-9-24-78(47)65(102)48-15-10-25-79(48)63(100)40(22-26-103-4)70-49(84)31-67-62(99)53(34(2)81)76-60(97)41(69-35(3)82)27-36-11-6-5-7-12-36)55(92)72-43(29-51(87)88)58(95)71-39(20-21-50(85)86)56(93)74-44(30-52(89)90)59(96)73-42(28-37-16-18-38(83)19-17-37)57(94)75-45(32-80)64(101)77-23-8-13-46(77)54(66)91/h5-7,11-12,16-19,33-34,39-48,53,80-81,83H,8-10,13-15,20-32H2,1-4H3,(H2,66,91)(H,67,99)(H,68,98)(H,69,82)(H,70,84)(H,71,95)(H,72,92)(H,73,96)(H,74,93)(H,75,94)(H,76,97)(H,85,86)(H,87,88)(H,89,90)/t33-,34+,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,53-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 1.85E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214153
(CHEMBL216711)Show SMILES CSCC[C@H](NC(=O)CNC(=O)[C@@H](NC(C)=O)[C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C56H81N13O22S/c1-27(59-52(87)39-9-6-19-68(39)56(91)40-10-7-20-69(40)54(89)33(17-21-92-4)61-41(74)25-58-53(88)45(28(2)71)60-29(3)72)47(82)63-35(23-43(77)78)50(85)62-32(15-16-42(75)76)48(83)65-36(24-44(79)80)51(86)64-34(22-30-11-13-31(73)14-12-30)49(84)66-37(26-70)55(90)67-18-5-8-38(67)46(57)81/h11-14,27-28,32-40,45,70-71,73H,5-10,15-26H2,1-4H3,(H2,57,81)(H,58,88)(H,59,87)(H,60,72)(H,61,74)(H,62,85)(H,63,82)(H,64,86)(H,65,83)(H,66,84)(H,75,76)(H,77,78)(H,79,80)/t27-,28+,32-,33-,34-,35-,36-,37-,38-,39-,40-,45-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 2.05E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214161
(CHEMBL415172)Show SMILES CSCC[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(C)=O)[C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C69H96N16O25S/c1-34(58(99)77-45(30-54(94)95)62(103)76-40(20-21-53(92)93)59(100)80-46(31-55(96)97)63(104)78-42(28-38-16-18-39(89)19-17-38)60(101)81-47(33-86)68(109)83-23-8-13-48(83)57(71)98)73-65(106)49-14-9-24-84(49)69(110)50-15-10-25-85(50)67(108)41(22-26-111-4)75-52(91)32-72-66(107)56(35(2)87)82-64(105)43(27-37-11-6-5-7-12-37)79-61(102)44(29-51(70)90)74-36(3)88/h5-7,11-12,16-19,34-35,40-50,56,86-87,89H,8-10,13-15,20-33H2,1-4H3,(H2,70,90)(H2,71,98)(H,72,107)(H,73,106)(H,74,88)(H,75,91)(H,76,103)(H,77,99)(H,78,104)(H,79,102)(H,80,100)(H,81,101)(H,82,105)(H,92,93)(H,94,95)(H,96,97)/t34-,35+,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,56-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 2.70E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 1/2
(Homo sapiens (Human)) | BDBM50214175
(CHEMBL410027)Show SMILES CSCC[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(C)=O)[C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(N)=O Show InChI InChI=1S/C75H107N17O26S/c1-37(2)29-46(80-40(5)95)65(108)86-49(32-56(76)97)67(110)85-48(30-41-13-8-7-9-14-41)70(113)89-61(39(4)94)72(115)78-35-57(98)81-45(24-28-119-6)73(116)92-27-12-17-55(92)75(118)91-26-11-16-54(91)71(114)79-38(3)63(106)83-50(33-59(101)102)68(111)82-44(22-23-58(99)100)64(107)87-51(34-60(103)104)69(112)84-47(31-42-18-20-43(96)21-19-42)66(109)88-52(36-93)74(117)90-25-10-15-53(90)62(77)105/h7-9,13-14,18-21,37-39,44-55,61,93-94,96H,10-12,15-17,22-36H2,1-6H3,(H2,76,97)(H2,77,105)(H,78,115)(H,79,114)(H,80,95)(H,81,98)(H,82,111)(H,83,106)(H,84,112)(H,85,110)(H,86,108)(H,87,107)(H,88,109)(H,89,113)(H,99,100)(H,101,102)(H,103,104)/t38-,39+,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,61-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 3.10E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibitory activity against interleukin-8 receptor using [125I]IL8 |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2P55QP3 |
More data for this
Ligand-Target Pair | |
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