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Compile Data Set for Download or QSAR

Found 9 hits of ki for UniProtKB: P20288   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D(1A)/D(2) dopamine receptor


(BOVINE)
BDBM52987
PNG
((6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...)
Show SMILES CCCN1CCc2cc(O)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31
Show InChI InChI=1S/C19H21NO3/c1-2-6-20-7-5-12-8-13(21)10-14-17(12)15(20)9-11-3-4-16(22)19(23)18(11)14/h3-4,8,10,15,21-23H,2,5-7,9H2,1H3/t15-/m1/s1
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1.20n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Agonistic activity against calf striatal Dopamine receptor using [3H]- ADTN radioligand


J Med Chem 33: 1800-5 (1990)


BindingDB Entry DOI: 10.7270/Q2K35SMD
More data for this
Ligand-Target Pair
D(1A)/D(2) dopamine receptor


(BOVINE)
BDBM50007422
PNG
((+)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...)
Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r|
Show InChI InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3/t15-/m1/s1
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1.5n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Agonistic activity against calf striatal Dopamine receptor using [3H]- ADTN radioligand


J Med Chem 33: 1800-5 (1990)


BindingDB Entry DOI: 10.7270/Q2K35SMD
More data for this
Ligand-Target Pair
D(1A)/D(2) dopamine receptor


(BOVINE)
BDBM50010698
PNG
((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Show SMILES CN1CCc2cc(O)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r|
Show InChI InChI=1S/C17H17NO3/c1-18-5-4-10-6-11(19)8-12-15(10)13(18)7-9-2-3-14(20)17(21)16(9)12/h2-3,6,8,13,19-21H,4-5,7H2,1H3/t13-/m1/s1
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2.20n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Agonistic activity against calf striatal Dopamine receptor using [3H]- ADTN radioligand


J Med Chem 33: 1800-5 (1990)


BindingDB Entry DOI: 10.7270/Q2K35SMD
More data for this
Ligand-Target Pair
D(1A)/D(2) dopamine receptor


(BOVINE)
BDBM50001955
PNG
((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r|
Show InChI InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1
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3.70n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Agonistic activity against calf striatal Dopamine receptor using [3H]- ADTN radioligand


J Med Chem 33: 1800-5 (1990)


BindingDB Entry DOI: 10.7270/Q2K35SMD
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
D(1A)/D(2) dopamine receptor


(BOVINE)
BDBM50010692
PNG
((R)-(-)-2-methoxy-N-npropylnorapomorphine | (R)-2-...)
Show SMILES CCCN1CCc2cc(OC)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31
Show InChI InChI=1S/C20H23NO3/c1-3-7-21-8-6-13-9-14(24-2)11-15-18(13)16(21)10-12-4-5-17(22)20(23)19(12)15/h4-5,9,11,16,22-23H,3,6-8,10H2,1-2H3/t16-/m1/s1
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3.80n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Agonistic activity against calf striatal Dopamine receptor using [3H]- ADTN radioligand


J Med Chem 33: 1800-5 (1990)


BindingDB Entry DOI: 10.7270/Q2K35SMD
More data for this
Ligand-Target Pair
D(1A)/D(2) dopamine receptor


(BOVINE)
BDBM50010697
PNG
((R)-(-)-2-methoxyapomorphine | (R)-2-Methoxy-6-met...)
Show SMILES COc1cc2CCN(C)[C@@H]3Cc4ccc(O)c(O)c4-c(c1)c23 |r|
Show InChI InChI=1S/C18H19NO3/c1-19-6-5-11-7-12(22-2)9-13-16(11)14(19)8-10-3-4-15(20)18(21)17(10)13/h3-4,7,9,14,20-21H,5-6,8H2,1-2H3/t14-/m1/s1
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16n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Agonistic activity against calf striatal Dopamine receptor using [3H]- ADTN radioligand


J Med Chem 33: 1800-5 (1990)


BindingDB Entry DOI: 10.7270/Q2K35SMD
More data for this
Ligand-Target Pair
D(1A)/D(2) dopamine receptor


(BOVINE)
BDBM29643
PNG
((6aS)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...)
Show SMILES CN1CCc2cccc-3c2[C@@H]1Cc1ccc(O)c(O)c-31
Show InChI InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m0/s1
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47n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Agonistic activity against calf striatal Dopamine receptor using [3H]- ADTN radioligand


J Med Chem 33: 1800-5 (1990)


BindingDB Entry DOI: 10.7270/Q2K35SMD
More data for this
Ligand-Target Pair
D(1A)/D(2) dopamine receptor


(BOVINE)
BDBM50010694
PNG
(2-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[...)
Show SMILES COc1cc2CCN(C)[C@H]3Cc4ccc(O)c(O)c4-c(c1)c23
Show InChI InChI=1S/C18H19NO3/c1-19-6-5-11-7-12(22-2)9-13-16(11)14(19)8-10-3-4-15(20)18(21)17(10)13/h3-4,7,9,14,20-21H,5-6,8H2,1-2H3/t14-/m0/s1
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162n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Agonistic activity against calf striatal Dopamine receptor using [3H]- ADTN radioligand


J Med Chem 33: 1800-5 (1990)


BindingDB Entry DOI: 10.7270/Q2K35SMD
More data for this
Ligand-Target Pair
D(1A)/D(2) dopamine receptor


(BOVINE)
BDBM50010699
PNG
((+)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Show SMILES CN1CCc2cc(O)cc-3c2[C@@H]1Cc1ccc(O)c(O)c-31
Show InChI InChI=1S/C17H17NO3/c1-18-5-4-10-6-11(19)8-12-15(10)13(18)7-9-2-3-14(20)17(21)16(9)12/h2-3,6,8,13,19-21H,4-5,7H2,1H3/t13-/m0/s1
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511n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Agonistic activity against calf striatal Dopamine receptor using [3H]- ADTN radioligand


J Med Chem 33: 1800-5 (1990)


BindingDB Entry DOI: 10.7270/Q2K35SMD
More data for this
Ligand-Target Pair