Compile Data Set for Download or QSAR

Found 85 hits of ic50 for UniProtKB: P19643   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM15581 (CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI InChI=1S/C13H15Cl2NO/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15/h1,5-6,10H,4,7-9H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro Inhibitory activity of Monoamine oxidase at rat hyphalamic mitochondrial 5-HT by displacing 2.5 uM of [14C]5-HT (serotonin)				J Med Chem 26: 1036-42 (1983) BindingDB Entry DOI: 10.7270/Q2K076FV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50224952 (CHEMBL441014) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC=C=C Show InChI InChI=1S/C14H17Cl2NO/c1-3-4-8-17(2)9-5-10-18-14-7-6-12(15)11-13(14)16/h4,6-7,11H,1,5,8-10H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Monoamine oxidase at rat hyphalamic mitochondrial 5-HT by displacing 2.5 uM of [14C]5-HT.				J Med Chem 26: 1036-42 (1983) BindingDB Entry DOI: 10.7270/Q2K076FV
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50225462 (CHEMBL554775) Show SMILES Cl.COc1cccc(c1)C(\CN)=C/F Show InChI InChI=1S/C10H12FNO/c1-13-10-4-2-3-8(5-10)9(6-11)7-12/h2-6H,7,12H2,1H3/b9-6-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against rat brain mitochondrial Monoamine oxidase				J Med Chem 28: 186-93 (1985) BindingDB Entry DOI: 10.7270/Q26M3910
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50225466 (CHEMBL544509) Show SMILES Cl.NC\C(=C\F)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C10H9F4N/c11-5-8(6-15)7-2-1-3-9(4-7)10(12,13)14/h1-5H,6,15H2/b8-5-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against rat brain mitochondrial Monoamine oxidase				J Med Chem 28: 186-93 (1985) BindingDB Entry DOI: 10.7270/Q26M3910
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50225455 (CHEMBL555332) Show SMILES Cl.Cc1ccc(cc1)C(\CN)=C/F Show InChI InChI=1S/C10H12FN/c1-8-2-4-9(5-3-8)10(6-11)7-12/h2-6H,7,12H2,1H3/b10-6-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against rat brain mitochondrial Monoamine oxidase				J Med Chem 28: 186-93 (1985) BindingDB Entry DOI: 10.7270/Q26M3910
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM15579 (CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...) Show SMILES C[C@H](Cc1ccccc1)N(C)CC#C |r| Show InChI InChI=1S/C13H17N/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13/h1,5-9,12H,10-11H2,2-3H3/t12-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Monoamine oxidase at rat hyphalamic mitochondrial PEA by displacing 2.5 uM of [14C]PEA.				J Med Chem 26: 1036-42 (1983) BindingDB Entry DOI: 10.7270/Q2K076FV
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50225456 (CHEMBL545207) Show SMILES Cl.NC\C(=C\F)c1ccccc1 Show InChI InChI=1S/C9H10FN/c10-6-9(7-11)8-4-2-1-3-5-8/h1-6H,7,11H2/b9-6-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against rat brain mitochondrial Monoamine oxidase				J Med Chem 28: 186-93 (1985) BindingDB Entry DOI: 10.7270/Q26M3910
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50225453 (CHEMBL541803) Show SMILES Cl.NC\C(=C\F)c1ccc(Cl)cc1 Show InChI InChI=1S/C9H9ClFN/c10-9-3-1-7(2-4-9)8(5-11)6-12/h1-5H,6,12H2/b8-5-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against rat brain mitochondrial Monoamine oxidase				J Med Chem 28: 186-93 (1985) BindingDB Entry DOI: 10.7270/Q26M3910
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM15579 (CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...) Show SMILES C[C@H](Cc1ccccc1)N(C)CC#C |r| Show InChI InChI=1S/C13H17N/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13/h1,5-9,12H,10-11H2,2-3H3/t12-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against rat brain mitochondrial Monoamine oxidase				J Med Chem 28: 186-93 (1985) BindingDB Entry DOI: 10.7270/Q26M3910
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50224950 (CHEMBL8877) Show SMILES NCC(Cc1ccc(Cl)cc1)=C=C Show InChI InChI=1S/C11H12ClN/c1-2-9(8-13)7-10-3-5-11(12)6-4-10/h3-6H,1,7-8,13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Monoamine oxidase at rat hyphalamic mitochondrial PEA by displacing 2.5 uM of [14C]PEA.				J Med Chem 26: 1036-42 (1983) BindingDB Entry DOI: 10.7270/Q2K076FV
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50225463 (CHEMBL538992) Show SMILES Cl.NC\C(=C\F)c1cccc(O)c1 Show InChI InChI=1S/C9H10FNO/c10-5-8(6-11)7-2-1-3-9(12)4-7/h1-5,12H,6,11H2/b8-5-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against rat brain mitochondrial Monoamine oxidase				J Med Chem 28: 186-93 (1985) BindingDB Entry DOI: 10.7270/Q26M3910
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50225449 (CHEMBL543328) Show SMILES Cl.COc1ccc(cc1)C(\CN)=C/F Show InChI InChI=1S/C10H12FNO/c1-13-10-4-2-8(3-5-10)9(6-11)7-12/h2-6H,7,12H2,1H3/b9-6-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against rat brain mitochondrial Monoamine oxidase				J Med Chem 28: 186-93 (1985) BindingDB Entry DOI: 10.7270/Q26M3910
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50225452 (CHEMBL553995) Show SMILES Cl.NC\C(=C\F)c1ccc(O)c(O)c1 Show InChI InChI=1S/C9H10FNO2/c10-4-7(5-11)6-1-2-8(12)9(13)3-6/h1-4,12-13H,5,11H2/b7-4-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against rat brain mitochondrial Monoamine oxidase				J Med Chem 28: 186-93 (1985) BindingDB Entry DOI: 10.7270/Q26M3910
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50224947 (CHEMBL8848) Show SMILES NCC(Cc1ccccc1)=C=C Show InChI InChI=1S/C11H13N/c1-2-10(9-12)8-11-6-4-3-5-7-11/h3-7H,1,8-9,12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Monoamine oxidase at rat hyphalamic mitochondrial PEA by displacing 2.5 uM of [14C]PEA.				J Med Chem 26: 1036-42 (1983) BindingDB Entry DOI: 10.7270/Q2K076FV
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50225464 (CHEMBL545677) Show SMILES Cl.NC\C(=C/F)c1ccccc1 Show InChI InChI=1S/C9H10FN/c10-6-9(7-11)8-4-2-1-3-5-8/h1-6H,7,11H2/b9-6+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against rat brain mitochondrial Monoamine oxidase				J Med Chem 28: 186-93 (1985) BindingDB Entry DOI: 10.7270/Q26M3910
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50224967 (CHEMBL275108) Show SMILES C=C=CCNCc1ccccc1 Show InChI InChI=1S/C11H13N/c1-2-3-9-12-10-11-7-5-4-6-8-11/h3-8,12H,1,9-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Monoamine oxidase at rat hyphalamic mitochondrial PEA by displacing 2.5 uM of [14C]PEA.				J Med Chem 26: 1036-42 (1983) BindingDB Entry DOI: 10.7270/Q2K076FV
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50224970 (CHEMBL8695) Show SMILES CN(CC=C=C)Cc1ccccc1 Show InChI InChI=1S/C12H15N/c1-3-4-10-13(2)11-12-8-6-5-7-9-12/h4-9H,1,10-11H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Monoamine oxidase at rat hyphalamic mitochondrial PEA by displacing 2.5 uM of [14C]PEA.				J Med Chem 26: 1036-42 (1983) BindingDB Entry DOI: 10.7270/Q2K076FV
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50025082 (2-(4-Chloro-2,3-dihydro-1H-indol-5-yl)-1-methyl-et...) Show SMILES CC(N)Cc1ccc2NCCc2c1Cl Show InChI InChI=1S/C11H15ClN2/c1-7(13)6-8-2-3-10-9(11(8)12)4-5-14-10/h2-3,7,14H,4-6,13H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of MAO by using [14C]5-HT as substrate in rat brain mitochondrial preparation				J Med Chem 29: 1406-12 (1986) BindingDB Entry DOI: 10.7270/Q29022S9
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50003138 (CHEMBL542711 | Methyl-(1-methyl-nonyl)-prop-2-ynyl...) Show SMILES CCCCCCCCC(C)N(C)CC#C Show InChI InChI=1S/C14H27N/c1-5-7-8-9-10-11-12-14(3)15(4)13-6-2/h2,14H,5,7-13H2,1,3-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
University of Saskatchewan Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of deamination of dopamine (DA) by MAO at 5 x 10e-4 M				J Med Chem 35: 3705-13 (1992) BindingDB Entry DOI: 10.7270/Q2GF0V4K
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50224948 (CHEMBL8712) Show SMILES NCC(=C=C)c1ccccc1 Show InChI InChI=1S/C10H11N/c1-2-9(8-11)10-6-4-3-5-7-10/h3-7H,1,8,11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Monoamine oxidase at rat hyphalamic mitochondrial PEA by displacing 2.5 uM of [14C]PEA.				J Med Chem 26: 1036-42 (1983) BindingDB Entry DOI: 10.7270/Q2K076FV
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50224950 (CHEMBL8877) Show SMILES NCC(Cc1ccc(Cl)cc1)=C=C Show InChI InChI=1S/C11H12ClN/c1-2-9(8-13)7-10-3-5-11(12)6-4-10/h3-6H,1,7-8,13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Monoamine oxidase at rat hyphalamic mitochondrial 5-HT by displacing 2.5 uM of [14C]5-HT.				J Med Chem 26: 1036-42 (1983) BindingDB Entry DOI: 10.7270/Q2K076FV
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM15579 (CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...) Show SMILES C[C@H](Cc1ccccc1)N(C)CC#C |r| Show InChI InChI=1S/C13H17N/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13/h1,5-9,12H,10-11H2,2-3H3/t12-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
University of Saskatchewan Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of deamination of dopamine (DA) by MAO at 5 x 10e-4 M				J Med Chem 35: 3705-13 (1992) BindingDB Entry DOI: 10.7270/Q2GF0V4K
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50003149 (CHEMBL542465 | Methyl-(1-methyl-undecyl)-prop-2-yn...) Show SMILES CCCCCCCCCCC(C)N(C)CC#C Show InChI InChI=1S/C16H31N/c1-5-7-8-9-10-11-12-13-14-16(3)17(4)15-6-2/h2,16H,5,7-15H2,1,3-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
University of Saskatchewan Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of deamination of dopamine (DA) by MAO at 5 x 10e-4 M				J Med Chem 35: 3705-13 (1992) BindingDB Entry DOI: 10.7270/Q2GF0V4K
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50003140 (CHEMBL541325 | Methyl-(1-methyl-hexyl)-prop-2-ynyl...) Show SMILES CCCCCC(C)N(C)CC#C Show InChI InChI=1S/C11H21N/c1-5-7-8-9-11(3)12(4)10-6-2/h2,11H,5,7-10H2,1,3-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
University of Saskatchewan Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of deamination of dopamine (DA) by MAO at 5 x 10e-4 M				J Med Chem 35: 3705-13 (1992) BindingDB Entry DOI: 10.7270/Q2GF0V4K
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50025084 (2-(1-Ethyl-6-methyl-2,3-dihydro-1H-indol-5-yl)-1-m...) Show SMILES CCN1CCc2cc(CC(C)N)c(C)cc12 Show InChI InChI=1S/C14H22N2/c1-4-16-6-5-12-9-13(8-11(3)15)10(2)7-14(12)16/h7,9,11H,4-6,8,15H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of MAO by using [14C]5-HT as substrate in rat brain mitochondrial preparation				J Med Chem 29: 1406-12 (1986) BindingDB Entry DOI: 10.7270/Q29022S9
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50224965 (CHEMBL268167) Show SMILES Cc1ccc(CC(CN)=C=C)cc1 Show InChI InChI=1S/C12H15N/c1-3-11(9-13)8-12-6-4-10(2)5-7-12/h4-7H,1,8-9,13H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Monoamine oxidase at rat hyphalamic mitochondrial PEA by displacing 2.5 uM of [14C]PEA.				J Med Chem 26: 1036-42 (1983) BindingDB Entry DOI: 10.7270/Q2K076FV
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50224966 (CHEMBL8467) Show SMILES CN(CC=C=C)C1CCc2ccccc12 Show InChI InChI=1S/C14H17N/c1-3-4-11-15(2)14-10-9-12-7-5-6-8-13(12)14/h4-8,14H,1,9-11H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Monoamine oxidase at rat hyphalamic mitochondrial PEA by displacing 2.5 uM of [14C]PEA.				J Med Chem 26: 1036-42 (1983) BindingDB Entry DOI: 10.7270/Q2K076FV
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50224953 (CHEMBL9068) Show SMILES CNCC(Cc1ccccc1)=C=C Show InChI InChI=1S/C12H15N/c1-3-11(10-13-2)9-12-7-5-4-6-8-12/h4-8,13H,1,9-10H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Monoamine oxidase at rat hyphalamic mitochondrial PEA by displacing 2.5 uM of [14C]PEA.				J Med Chem 26: 1036-42 (1983) BindingDB Entry DOI: 10.7270/Q2K076FV
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50003139 (CHEMBL545755 | sec-Butyl-methyl-prop-2-ynyl-amine;...) Show SMILES CCC(C)N(C)CC#C Show InChI InChI=1S/C8H15N/c1-5-7-9(4)8(3)6-2/h1,8H,6-7H2,2-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
University of Saskatchewan Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of deamination of dopamine (DA) by MAO at 5 x 10e-4 M				J Med Chem 35: 3705-13 (1992) BindingDB Entry DOI: 10.7270/Q2GF0V4K
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50224971 (CHEMBL8974) Show SMILES COc1ccc(CC(CN)=C=C)cc1 Show InChI InChI=1S/C12H15NO/c1-3-10(9-13)8-11-4-6-12(14-2)7-5-11/h4-7H,1,8-9,13H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Monoamine oxidase at rat hyphalamic mitochondrial PEA by displacing 2.5 uM of [14C]PEA.				J Med Chem 26: 1036-42 (1983) BindingDB Entry DOI: 10.7270/Q2K076FV
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50025080 (1-(4-Chloro-2,3-dihydro-1H-indol-5-ylmethyl)-propy...) Show SMILES CCC(N)Cc1ccc2NCCc2c1Cl Show InChI InChI=1S/C12H17ClN2/c1-2-9(14)7-8-3-4-11-10(12(8)13)5-6-15-11/h3-4,9,15H,2,5-7,14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of MAO by using [14C]5-HT as substrate in rat brain mitochondrial preparation				J Med Chem 29: 1406-12 (1986) BindingDB Entry DOI: 10.7270/Q29022S9
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM15579 (CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...) Show SMILES C[C@H](Cc1ccccc1)N(C)CC#C |r| Show InChI InChI=1S/C13H17N/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13/h1,5-9,12H,10-11H2,2-3H3/t12-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Monoamine oxidase at rat hyphalamic mitochondrial 5-HT by displacing 2.5 uM of [14C]5-HT.				J Med Chem 26: 1036-42 (1983) BindingDB Entry DOI: 10.7270/Q2K076FV
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM15581 (CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI InChI=1S/C13H15Cl2NO/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15/h1,5-6,10H,4,7-9H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro Inhibitory activity of Monoamine oxidase at rat hyphalamic mitochondrial PEA by displacing 2.5 uM of [14C]PEA (phenethylamine)				J Med Chem 26: 1036-42 (1983) BindingDB Entry DOI: 10.7270/Q2K076FV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50224971 (CHEMBL8974) Show SMILES COc1ccc(CC(CN)=C=C)cc1 Show InChI InChI=1S/C12H15NO/c1-3-10(9-13)8-11-4-6-12(14-2)7-5-11/h4-7H,1,8-9,13H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Monoamine oxidase at rat hyphalamic mitochondrial 5-HT by displacing 2.5 uM of [14C]5-HT.				J Med Chem 26: 1036-42 (1983) BindingDB Entry DOI: 10.7270/Q2K076FV
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50025079 (CHEMBL30344 | [4-(2-Amino-propyl)-3-methyl-phenyl]...) Show SMILES CC(N)Cc1ccc(cc1C)N(C)C Show InChI InChI=1S/C12H20N2/c1-9-7-12(14(3)4)6-5-11(9)8-10(2)13/h5-7,10H,8,13H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of MAO by using [14C]5-HT as substrate in rat brain mitochondrial preparation				J Med Chem 29: 1406-12 (1986) BindingDB Entry DOI: 10.7270/Q29022S9
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50224951 (CHEMBL269593) Show SMILES CC(Cc1ccccc1)N(C)CC=C=C Show InChI InChI=1S/C14H19N/c1-4-5-11-15(3)13(2)12-14-9-7-6-8-10-14/h5-10,13H,1,11-12H2,2-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Monoamine oxidase at rat hyphalamic mitochondrial 5-HT by displacing 2.5 uM of [14C]5-HT.				J Med Chem 26: 1036-42 (1983) BindingDB Entry DOI: 10.7270/Q2K076FV
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50025086 (1-Methyl-2-(4-methyl-2,3-dihydro-1H-indol-5-yl)-et...) Show SMILES CC(N)Cc1ccc2NCCc2c1C Show InChI InChI=1S/C12H18N2/c1-8(13)7-10-3-4-12-11(9(10)2)5-6-14-12/h3-4,8,14H,5-7,13H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of MAO by using [14C]5-HT as substrate in rat brain mitochondrial preparation				J Med Chem 29: 1406-12 (1986) BindingDB Entry DOI: 10.7270/Q29022S9
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50224965 (CHEMBL268167) Show SMILES Cc1ccc(CC(CN)=C=C)cc1 Show InChI InChI=1S/C12H15N/c1-3-11(9-13)8-12-6-4-10(2)5-7-12/h4-7H,1,8-9,13H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Monoamine oxidase at rat hyphalamic mitochondrial 5-HT by displacing 2.5 uM of [14C]5-HT.				J Med Chem 26: 1036-42 (1983) BindingDB Entry DOI: 10.7270/Q2K076FV
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50025085 (2-(1-Ethyl-4-methyl-2,3-dihydro-1H-indol-5-yl)-1-m...) Show SMILES CCN1CCc2c1ccc(CC(C)N)c2C Show InChI InChI=1S/C14H22N2/c1-4-16-8-7-13-11(3)12(9-10(2)15)5-6-14(13)16/h5-6,10H,4,7-9,15H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of MAO by using [14C]5-HT as substrate in rat brain mitochondrial preparation				J Med Chem 29: 1406-12 (1986) BindingDB Entry DOI: 10.7270/Q29022S9
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50025080 (1-(4-Chloro-2,3-dihydro-1H-indol-5-ylmethyl)-propy...) Show SMILES CCC(N)Cc1ccc2NCCc2c1Cl Show InChI InChI=1S/C12H17ClN2/c1-2-9(14)7-8-3-4-11-10(12(8)13)5-6-15-11/h3-4,9,15H,2,5-7,14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of MAO by using [14C]phenylethylamine as substrate in rat brain mitochondrial preparation				J Med Chem 29: 1406-12 (1986) BindingDB Entry DOI: 10.7270/Q29022S9
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50224966 (CHEMBL8467) Show SMILES CN(CC=C=C)C1CCc2ccccc12 Show InChI InChI=1S/C14H17N/c1-3-4-11-15(2)14-10-9-12-7-5-6-8-13(12)14/h4-8,14H,1,9-11H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Monoamine oxidase at rat hyphalamic mitochondrial 5-HT by displacing 2.5 uM of [14C]5-HT.				J Med Chem 26: 1036-42 (1983) BindingDB Entry DOI: 10.7270/Q2K076FV
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50224967 (CHEMBL275108) Show SMILES C=C=CCNCc1ccccc1 Show InChI InChI=1S/C11H13N/c1-2-3-9-12-10-11-7-5-4-6-8-11/h3-8,12H,1,9-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Monoamine oxidase at rat hyphalamic mitochondrial 5-HT by displacing 2.5 uM of [14C]5-HT.				J Med Chem 26: 1036-42 (1983) BindingDB Entry DOI: 10.7270/Q2K076FV
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50452531 (CHEMBL2028089) Show SMILES OC(=O)C(O)=O.CC=C=CCN(C)Cc1ccccc1 |(21.28,-8.31,;19.74,-8.31,;18.97,-6.98,;18.97,-9.64,;17.43,-9.64,;19.74,-10.98,;19.44,-4.47,;18.11,-3.7,;16.61,-4.07,;15.12,-4.46,;13.79,-3.65,;12.45,-4.41,;11.12,-3.62,;12.42,-5.95,;11.08,-6.7,;9.76,-5.91,;8.41,-6.66,;8.39,-8.2,;9.72,-8.99,;11.05,-8.23,)| Show InChI InChI=1S/C13H17N.C2H2O4/c1-3-4-8-11-14(2)12-13-9-6-5-7-10-13;3-1(4)2(5)6/h3,5-10H,11-12H2,1-2H3;(H,3,4)(H,5,6)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Monoamine oxidase at rat hyphalamic mitochondrial PEA by displacing 2.5 uM of [14C]PEA.				J Med Chem 26: 1036-42 (1983) BindingDB Entry DOI: 10.7270/Q2K076FV
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50452531 (CHEMBL2028089) Show SMILES OC(=O)C(O)=O.CC=C=CCN(C)Cc1ccccc1 |(21.28,-8.31,;19.74,-8.31,;18.97,-6.98,;18.97,-9.64,;17.43,-9.64,;19.74,-10.98,;19.44,-4.47,;18.11,-3.7,;16.61,-4.07,;15.12,-4.46,;13.79,-3.65,;12.45,-4.41,;11.12,-3.62,;12.42,-5.95,;11.08,-6.7,;9.76,-5.91,;8.41,-6.66,;8.39,-8.2,;9.72,-8.99,;11.05,-8.23,)| Show InChI InChI=1S/C13H17N.C2H2O4/c1-3-4-8-11-14(2)12-13-9-6-5-7-10-13;3-1(4)2(5)6/h3,5-10H,11-12H2,1-2H3;(H,3,4)(H,5,6)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Monoamine oxidase at rat hyphalamic mitochondrial PEA by displacing 2.5 uM of [14C]PEA.				J Med Chem 26: 1036-42 (1983) BindingDB Entry DOI: 10.7270/Q2K076FV
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50225457 (CHEMBL538744) Show SMILES Cl.COc1ccccc1\C(CN)=C/F Show InChI InChI=1S/C10H12FNO/c1-13-10-5-3-2-4-9(10)8(6-11)7-12/h2-6H,7,12H2,1H3/b8-6-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against rat brain mitochondrial Monoamine oxidase				J Med Chem 28: 186-93 (1985) BindingDB Entry DOI: 10.7270/Q26M3910
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50261815 (2-(3,4-dimethoxyphenyl)-3-fluoroprop-2-en-1-amine ...) Show SMILES COc1ccc(cc1OC)C(\CN)=C/F Show InChI InChI=1S/C11H14FNO2/c1-14-10-4-3-8(5-11(10)15-2)9(6-12)7-13/h3-6H,7,13H2,1-2H3/b9-6-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against rat brain mitochondrial Monoamine oxidase				J Med Chem 28: 186-93 (1985) BindingDB Entry DOI: 10.7270/Q26M3910
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50025083 (2-(2,3-Dihydro-1H-indol-5-yl)-1,1-dimethyl-ethylam...) Show SMILES CC(C)(N)Cc1ccc2NCCc2c1 Show InChI InChI=1S/C12H18N2/c1-12(2,13)8-9-3-4-11-10(7-9)5-6-14-11/h3-4,7,14H,5-6,8,13H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of MAO by using [14C]5-HT as substrate in rat brain mitochondrial preparation				J Med Chem 29: 1406-12 (1986) BindingDB Entry DOI: 10.7270/Q29022S9
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50224946 (CHEMBL8534) Show SMILES C=C=CCN1CCc2ccccc2C1 Show InChI InChI=1S/C13H15N/c1-2-3-9-14-10-8-12-6-4-5-7-13(12)11-14/h3-7H,1,8-11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Monoamine oxidase at rat hyphalamic mitochondrial PEA by displacing 2.5 uM of [14C]PEA.				J Med Chem 26: 1036-42 (1983) BindingDB Entry DOI: 10.7270/Q2K076FV
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50224952 (CHEMBL441014) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC=C=C Show InChI InChI=1S/C14H17Cl2NO/c1-3-4-8-17(2)9-5-10-18-14-7-6-12(15)11-13(14)16/h4,6-7,11H,1,5,8-10H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Monoamine oxidase at rat hyphalamic mitochondrial PEA by displacing 2.5 uM of [14C]PEA.				J Med Chem 26: 1036-42 (1983) BindingDB Entry DOI: 10.7270/Q2K076FV
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50224951 (CHEMBL269593) Show SMILES CC(Cc1ccccc1)N(C)CC=C=C Show InChI InChI=1S/C14H19N/c1-4-5-11-15(3)13(2)12-14-9-7-6-8-10-14/h5-10,13H,1,11-12H2,2-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Monoamine oxidase at rat hyphalamic mitochondrial PEA by displacing 2.5 uM of [14C]PEA.				J Med Chem 26: 1036-42 (1983) BindingDB Entry DOI: 10.7270/Q2K076FV
					More data for this Ligand-Target Pair

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