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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for UniProtKB: P22437   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin G/H synthase 1/2


(Mus musculus-Mus musculus (Mouse))
BDBM50229760
PNG
(CHEMBL316184 | WAY-121520)
Show SMILES Cc1c(CC(O)=O)c2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(Cl)cc1
Show InChI InChI=1S/C28H23ClN2O3/c1-18-24(15-28(32)33)25-14-23(34-17-22-11-8-20-4-2-3-5-26(20)30-22)12-13-27(25)31(18)16-19-6-9-21(29)10-7-19/h2-14H,15-17H2,1H3,(H,32,33)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 4n/an/an/an/an/an/a



Wyeth-Ayerst Research

Curated by ChEMBL


Assay Description
The compound was tested for inhibitory activity against Prostaglandin G/H synthase in mouse macrophage


J Med Chem 35: 2501-24 (1992)


BindingDB Entry DOI: 10.7270/Q23B60R4
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1/2


(Mus musculus-Mus musculus (Mouse))
BDBM50006795
PNG
(2-(Naphthalen-1-yloxymethyl)-quinoline | CHEMBL847...)
Show SMILES C(Oc1cccc2ccccc12)c1ccc2ccccc2n1
Show InChI InChI=1S/C20H15NO/c1-3-9-18-15(6-1)8-5-11-20(18)22-14-17-13-12-16-7-2-4-10-19(16)21-17/h1-13H,14H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 4.40E+4n/an/an/an/an/an/a



Wyeth-Ayerst Research

Curated by ChEMBL


Assay Description
The compound was tested for inhibitory activity against 5-lipoxygenase translocation inhibitor in RBL-2H3 cells


J Med Chem 35: 2501-24 (1992)


BindingDB Entry DOI: 10.7270/Q23B60R4
More data for this
Ligand-Target Pair