Found 31 hits of ic50 for UniProtKB: P21451 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Endothelin receptor type B/1 receptor
(RAT) | BDBM50045239
(Ac-D-Dip-Leu-Asp-Ile-Ile-Trp | Ac-D-Dip-Leu-Asp-Il...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](NC(C)=O)C(c1ccccc1)c1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C50H65N7O10/c1-8-29(5)42(47(63)55-39(50(66)67)25-34-27-51-36-23-17-16-22-35(34)36)57-48(64)43(30(6)9-2)56-46(62)38(26-40(59)60)53-45(61)37(24-28(3)4)54-49(65)44(52-31(7)58)41(32-18-12-10-13-19-32)33-20-14-11-15-21-33/h10-23,27-30,37-39,41-44,51H,8-9,24-26H2,1-7H3,(H,52,58)(H,53,61)(H,54,65)(H,55,63)(H,56,62)(H,57,64)(H,59,60)(H,66,67)/t29-,30-,37-,38-,39-,42-,43-,44+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50368647
(CHEMBL1788127)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC([O-])=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](NC(C)=O)C(c1ccccc1)c1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C([O-])=O |r| Show InChI InChI=1S/C50H65N7O10/c1-8-29(5)42(47(63)55-39(50(66)67)25-34-27-51-36-23-17-16-22-35(34)36)57-48(64)43(30(6)9-2)56-46(62)38(26-40(59)60)53-45(61)37(24-28(3)4)54-49(65)44(52-31(7)58)41(32-18-12-10-13-19-32)33-20-14-11-15-21-33/h10-23,27-30,37-39,41-44,51H,8-9,24-26H2,1-7H3,(H,52,58)(H,53,61)(H,54,65)(H,55,63)(H,56,62)(H,57,64)(H,59,60)(H,66,67)/p-2/t29-,30-,37-,38-,39-,42-,43-,44+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50045230
(Ac-D-Trp-Leu-Asp-Ile-Ile-Trp | CHEMBL313382)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C46H62N8O10/c1-8-25(5)39(44(61)52-37(46(63)64)20-29-23-48-33-17-13-11-15-31(29)33)54-45(62)40(26(6)9-2)53-43(60)36(21-38(56)57)51-41(58)34(18-24(3)4)50-42(59)35(49-27(7)55)19-28-22-47-32-16-12-10-14-30(28)32/h10-17,22-26,34-37,39-40,47-48H,8-9,18-21H2,1-7H3,(H,49,55)(H,50,59)(H,51,58)(H,52,61)(H,53,60)(H,54,62)(H,56,57)(H,63,64)/t25-,26-,34-,35-,36-,37-,39-,40-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50045244
((S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C47H59N7O10/c1-6-27(3)40(45(61)52-38(47(63)64)24-32-26-48-34-21-15-14-20-33(32)34)54-46(62)41(28(4)7-2)53-44(60)37(25-39(56)57)51-43(59)36(23-31-18-12-9-13-19-31)50-42(58)35(49-29(5)55)22-30-16-10-8-11-17-30/h8-21,26-28,35-38,40-41,48H,6-7,22-25H2,1-5H3,(H,49,55)(H,50,58)(H,51,59)(H,52,61)(H,53,60)(H,54,62)(H,56,57)(H,63,64)/t27-,28-,35+,36-,37-,38-,40-,41-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50045240
((S)-2-[(S)-2-((2S,5S)-2-{(S)-2-[(S)-2-((R)-2-Acety...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C49H65N7O8/c1-8-30(5)42(47(61)54-41(49(63)64)27-35-28-50-37-23-17-16-22-36(35)37)56-48(62)43(31(6)9-2)55-46(60)40(26-34-20-14-11-15-21-34)53-44(58)38(24-29(3)4)52-45(59)39(51-32(7)57)25-33-18-12-10-13-19-33/h10-23,28-31,38-43,50H,8-9,24-27H2,1-7H3,(H,51,57)(H,52,59)(H,53,58)(H,54,61)(H,55,60)(H,56,62)(H,63,64)/t30-,31-,38-,39+,40-,41-,42-,43-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50001219
(3-{2-[2-Acetylamino-3-(4-hydroxy-phenyl)-propionyl...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C44H61N7O11/c1-8-24(5)37(42(59)49-35(44(61)62)20-28-22-45-31-13-11-10-12-30(28)31)51-43(60)38(25(6)9-2)50-41(58)34(21-36(54)55)48-39(56)32(18-23(3)4)47-40(57)33(46-26(7)52)19-27-14-16-29(53)17-15-27/h10-17,22-25,32-35,37-38,45,53H,8-9,18-21H2,1-7H3,(H,46,52)(H,47,57)(H,48,56)(H,49,59)(H,50,58)(H,51,60)(H,54,55)(H,61,62)/t24-,25-,32-,33+,34-,35-,37-,38-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50045262
(Ac-D-Phe-Ala-Asp-Ile-Ile-Trp | CHEMBL406279)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C41H55N7O10/c1-7-22(3)34(39(55)46-32(41(57)58)19-27-21-42-29-17-13-12-16-28(27)29)48-40(56)35(23(4)8-2)47-38(54)31(20-33(50)51)45-36(52)24(5)43-37(53)30(44-25(6)49)18-26-14-10-9-11-15-26/h9-17,21-24,30-32,34-35,42H,7-8,18-20H2,1-6H3,(H,43,53)(H,44,49)(H,45,52)(H,46,55)(H,47,54)(H,48,56)(H,50,51)(H,57,58)/t22-,23-,24-,30+,31-,32-,34-,35-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50045227
((S)-3-[2-((R)-2-Acetylamino-3-phenyl-propionylamin...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCN)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C43H60N8O10/c1-6-24(3)36(41(58)49-34(43(60)61)21-28-23-45-30-17-12-11-16-29(28)30)51-42(59)37(25(4)7-2)50-40(57)33(22-35(53)54)48-38(55)31(18-13-19-44)47-39(56)32(46-26(5)52)20-27-14-9-8-10-15-27/h8-12,14-17,23-25,31-34,36-37,45H,6-7,13,18-22,44H2,1-5H3,(H,46,52)(H,47,56)(H,48,55)(H,49,58)(H,50,57)(H,51,59)(H,53,54)(H,60,61)/t24-,25-,31-,32+,33-,34-,36-,37-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50001217
(3-[2-(2-Acetylamino-3-phenyl-propionylamino)-4-met...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C44H61N7O10/c1-8-25(5)37(42(58)49-35(44(60)61)21-29-23-45-31-18-14-13-17-30(29)31)51-43(59)38(26(6)9-2)50-41(57)34(22-36(53)54)48-39(55)32(19-24(3)4)47-40(56)33(46-27(7)52)20-28-15-11-10-12-16-28/h10-18,23-26,32-35,37-38,45H,8-9,19-22H2,1-7H3,(H,46,52)(H,47,56)(H,48,55)(H,49,58)(H,50,57)(H,51,59)(H,53,54)(H,60,61)/t25-,26-,32-,33+,34-,35-,37-,38-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 740 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50045243
(Ac-D-Phe-Glu-Asp-Ile-Trp | CHEMBL313056)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C37H46N6O11/c1-4-20(2)32(36(52)42-29(37(53)54)17-23-19-38-25-13-9-8-12-24(23)25)43-35(51)28(18-31(47)48)41-33(49)26(14-15-30(45)46)40-34(50)27(39-21(3)44)16-22-10-6-5-7-11-22/h5-13,19-20,26-29,32,38H,4,14-18H2,1-3H3,(H,39,44)(H,40,50)(H,41,49)(H,42,52)(H,43,51)(H,45,46)(H,47,48)(H,53,54)/t20-,26-,27+,28-,29-,32-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 740 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50001221
(3-[2-(2-Acetylamino-3-naphthalen-2-yl-propionylami...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C48H63N7O10/c1-8-27(5)41(46(62)53-39(48(64)65)23-33-25-49-35-17-13-12-16-34(33)35)55-47(63)42(28(6)9-2)54-45(61)38(24-40(57)58)52-43(59)36(20-26(3)4)51-44(60)37(50-29(7)56)22-30-18-19-31-14-10-11-15-32(31)21-30/h10-19,21,25-28,36-39,41-42,49H,8-9,20,22-24H2,1-7H3,(H,50,56)(H,51,60)(H,52,59)(H,53,62)(H,54,61)(H,55,63)(H,57,58)(H,64,65)/t27-,28-,36-,37+,38-,39-,41-,42-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50045237
(Ac-D-Phe-Leu-Asp-Ala-Ile-Trp | CHEMBL87243)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C41H55N7O10/c1-7-23(4)35(40(56)47-33(41(57)58)19-27-21-42-29-16-12-11-15-28(27)29)48-36(52)24(5)43-37(53)32(20-34(50)51)46-38(54)30(17-22(2)3)45-39(55)31(44-25(6)49)18-26-13-9-8-10-14-26/h8-16,21-24,30-33,35,42H,7,17-20H2,1-6H3,(H,43,53)(H,44,49)(H,45,55)(H,46,54)(H,47,56)(H,48,52)(H,50,51)(H,57,58)/t23-,24-,30-,31+,32-,33-,35-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50045251
(3-((R)-2-Acetylamino-3-phenyl-propionylamino)-N-{(...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C38H50N6O9/c1-6-21(3)32(36(50)42-30(38(52)53)18-25-20-39-27-16-12-11-15-26(25)27)44-37(51)33(22(4)7-2)43-35(49)29(19-31(46)47)41-34(48)28(40-23(5)45)17-24-13-9-8-10-14-24/h8-16,20-22,28-30,32-33,39H,6-7,17-19H2,1-5H3,(H,40,45)(H,41,48)(H,42,50)(H,43,49)(H,44,51)(H,46,47)(H,52,53)/t21-,22-,28+,29-,30-,32-,33-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50045250
(Ac-D-Phe-Leu-Asp-Ile-Ile-Bta | CHEMBL315780)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H](C(O)=O)c1csc2ccccc12 Show InChI InChI=1S/C43H58N6O10S/c1-8-24(5)35(41(56)48-36(25(6)9-2)42(57)49-37(43(58)59)29-22-60-33-18-14-13-17-28(29)33)47-40(55)32(21-34(51)52)46-38(53)30(19-23(3)4)45-39(54)31(44-26(7)50)20-27-15-11-10-12-16-27/h10-18,22-25,30-32,35-37H,8-9,19-21H2,1-7H3,(H,44,50)(H,45,54)(H,46,53)(H,47,55)(H,48,56)(H,49,57)(H,51,52)(H,58,59)/t24-,25-,30-,31+,32-,35-,36-,37-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50000566
((S)-3-{(S)-2-[(R)-2-Acetylamino-3-(3H-imidazol-4-y...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1cnc[nH]1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C41H59N9O10/c1-8-22(5)34(39(57)48-32(41(59)60)15-25-18-43-28-13-11-10-12-27(25)28)50-40(58)35(23(6)9-2)49-38(56)31(17-33(52)53)47-36(54)29(14-21(3)4)46-37(55)30(45-24(7)51)16-26-19-42-20-44-26/h10-13,18-23,29-32,34-35,43H,8-9,14-17H2,1-7H3,(H,42,44)(H,45,51)(H,46,55)(H,47,54)(H,48,57)(H,49,56)(H,50,58)(H,52,53)(H,59,60)/t22-,23-,29-,30+,31-,32-,34-,35-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50001218
(3-[2-(2-Acetylamino-3-biphenyl-4-yl-propionylamino...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(C)=O)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C50H65N7O10/c1-8-29(5)43(48(64)55-41(50(66)67)25-35-27-51-37-18-14-13-17-36(35)37)57-49(65)44(30(6)9-2)56-47(63)40(26-42(59)60)54-45(61)38(23-28(3)4)53-46(62)39(52-31(7)58)24-32-19-21-34(22-20-32)33-15-11-10-12-16-33/h10-22,27-30,38-41,43-44,51H,8-9,23-26H2,1-7H3,(H,52,58)(H,53,62)(H,54,61)(H,55,64)(H,56,63)(H,57,65)(H,59,60)(H,66,67)/t29-,30-,38-,39+,40-,41-,43-,44-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50000566
((S)-3-{(S)-2-[(R)-2-Acetylamino-3-(3H-imidazol-4-y...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1cnc[nH]1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C41H59N9O10/c1-8-22(5)34(39(57)48-32(41(59)60)15-25-18-43-28-13-11-10-12-27(25)28)50-40(58)35(23(6)9-2)49-38(56)31(17-33(52)53)47-36(54)29(14-21(3)4)46-37(55)30(45-24(7)51)16-26-19-42-20-44-26/h10-13,18-23,29-32,34-35,43H,8-9,14-17H2,1-7H3,(H,42,44)(H,45,51)(H,46,55)(H,47,54)(H,48,57)(H,49,56)(H,50,58)(H,52,53)(H,59,60)/t22-,23-,29-,30+,31-,32-,34-,35-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50231133
(CHEMBL262166)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C43H57N7O12/c1-6-24(4)37(42(60)46-30(16-17-35(52)53)38(56)49-34(43(61)62)20-27-22-44-29-15-11-10-14-28(27)29)50-41(59)33(21-36(54)55)48-39(57)31(18-23(2)3)47-40(58)32(45-25(5)51)19-26-12-8-7-9-13-26/h7-15,22-24,30-34,37,44H,6,16-21H2,1-5H3,(H,45,51)(H,46,60)(H,47,58)(H,48,57)(H,49,56)(H,50,59)(H,52,53)(H,54,55)(H,61,62)/t24-,30-,31-,32+,33-,34-,37-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 5.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50045225
(Ac-D-Phe-Leu-Asp-Ile-Ala-Trp | CHEMBL86737)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C41H55N7O10/c1-7-23(4)35(40(56)43-24(5)36(52)47-33(41(57)58)19-27-21-42-29-16-12-11-15-28(27)29)48-39(55)32(20-34(50)51)46-37(53)30(17-22(2)3)45-38(54)31(44-25(6)49)18-26-13-9-8-10-14-26/h8-16,21-24,30-33,35,42H,7,17-20H2,1-6H3,(H,43,56)(H,44,49)(H,45,54)(H,46,53)(H,47,52)(H,48,55)(H,50,51)(H,57,58)/t23-,24-,30-,31+,32-,33-,35-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 6.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50045232
(Ac-D-Phe-Leu-Asp-Glu-Ile-Trp | CHEMBL431874)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C43H57N7O12/c1-6-24(4)37(42(60)49-34(43(61)62)20-27-22-44-29-15-11-10-14-28(27)29)50-38(56)30(16-17-35(52)53)46-41(59)33(21-36(54)55)48-39(57)31(18-23(2)3)47-40(58)32(45-25(5)51)19-26-12-8-7-9-13-26/h7-15,22-24,30-34,37,44H,6,16-21H2,1-5H3,(H,45,51)(H,46,59)(H,47,58)(H,48,57)(H,49,60)(H,50,56)(H,52,53)(H,54,55)(H,61,62)/t24-,30-,31-,32+,33-,34-,37-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50045260
(Ac-D-Phe-Leu-Lys-Ile-Ile-Trp | CHEMBL431218)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C46H68N8O8/c1-8-28(5)39(44(59)52-38(46(61)62)25-32-26-48-34-20-14-13-19-33(32)34)54-45(60)40(29(6)9-2)53-41(56)35(21-15-16-22-47)50-42(57)36(23-27(3)4)51-43(58)37(49-30(7)55)24-31-17-11-10-12-18-31/h10-14,17-20,26-29,35-40,48H,8-9,15-16,21-25,47H2,1-7H3,(H,49,55)(H,50,57)(H,51,58)(H,52,59)(H,53,56)(H,54,60)(H,61,62)/t28-,29-,35-,36-,37+,38-,39-,40-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50045265
(CHEMBL315328 | D-Phe-Leu-Asp-Ile-Ile-Trp)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](N)Cc1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C42H59N7O9/c1-7-24(5)35(40(55)47-33(42(57)58)20-27-22-44-30-17-13-12-16-28(27)30)49-41(56)36(25(6)8-2)48-39(54)32(21-34(50)51)46-38(53)31(18-23(3)4)45-37(52)29(43)19-26-14-10-9-11-15-26/h9-17,22-25,29,31-33,35-36,44H,7-8,18-21,43H2,1-6H3,(H,45,52)(H,46,53)(H,47,55)(H,48,54)(H,49,56)(H,50,51)(H,57,58)/t24-,25-,29+,31-,32-,33-,35-,36-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.24E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50231134
(CHEMBL2370061)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(C)=O)C(=O)N[C@H]([C@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C41H59N9O10/c1-8-22(5)34(39(57)48-32(41(59)60)15-25-18-43-28-13-11-10-12-27(25)28)50-40(58)35(23(6)9-2)49-38(56)31(17-33(52)53)47-36(54)29(14-21(3)4)46-37(55)30(45-24(7)51)16-26-19-42-20-44-26/h10-13,18-23,29-32,34-35,43H,8-9,14-17H2,1-7H3,(H,42,44)(H,45,51)(H,46,55)(H,47,54)(H,48,57)(H,49,56)(H,50,58)(H,52,53)(H,59,60)/t22-,23+,29+,30+,31+,32+,34-,35+/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.69E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50045235
((S)-3-[(R)-2-((1S,5S)-2-Acetylamino-3-phenyl-propi...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C38H50N6O9/c1-6-22(4)33(37(51)43-31(38(52)53)18-25-20-39-27-15-11-10-14-26(25)27)44-36(50)30(19-32(46)47)42-34(48)28(16-21(2)3)41-35(49)29(40-23(5)45)17-24-12-8-7-9-13-24/h7-15,20-22,28-31,33,39H,6,16-19H2,1-5H3,(H,40,45)(H,41,49)(H,42,48)(H,43,51)(H,44,50)(H,46,47)(H,52,53)/t22-,28-,29+,30-,31-,33-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.45E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50231136
(CHEMBL2370073)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C41H59N9O10/c1-8-22(5)34(39(57)48-32(41(59)60)15-25-18-43-28-13-11-10-12-27(25)28)50-40(58)35(23(6)9-2)49-38(56)31(17-33(52)53)47-36(54)29(14-21(3)4)46-37(55)30(45-24(7)51)16-26-19-42-20-44-26/h10-13,18-23,29-32,34-35,43H,8-9,14-17H2,1-7H3,(H,42,44)(H,45,51)(H,46,55)(H,47,54)(H,48,57)(H,49,56)(H,50,58)(H,52,53)(H,59,60)/t22-,23-,29-,30-,31+,32-,34-,35-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 3.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50231135
(CHEMBL2114215)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C41H59N9O10/c1-8-22(5)34(39(57)48-32(41(59)60)15-25-18-43-28-13-11-10-12-27(25)28)50-40(58)35(23(6)9-2)49-38(56)31(17-33(52)53)47-36(54)29(14-21(3)4)46-37(55)30(45-24(7)51)16-26-19-42-20-44-26/h10-13,18-23,29-32,34-35,43H,8-9,14-17H2,1-7H3,(H,42,44)(H,45,51)(H,46,55)(H,47,54)(H,48,57)(H,49,56)(H,50,58)(H,52,53)(H,59,60)/t22-,23-,29+,30-,31-,32-,34-,35-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 3.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50231137
(CHEMBL2369145)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C41H59N9O10/c1-8-22(5)34(39(57)48-32(41(59)60)15-25-18-43-28-13-11-10-12-27(25)28)50-40(58)35(23(6)9-2)49-38(56)31(17-33(52)53)47-36(54)29(14-21(3)4)46-37(55)30(45-24(7)51)16-26-19-42-20-44-26/h10-13,18-23,29-32,34-35,43H,8-9,14-17H2,1-7H3,(H,42,44)(H,45,51)(H,46,55)(H,47,54)(H,48,57)(H,49,56)(H,50,58)(H,52,53)(H,59,60)/t22-,23-,29-,30-,31-,32+,34-,35-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50045229
(Ac-D-Phe-Leu-Asp-Lys-Ile-Trp | CHEMBL314239)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C44H62N8O10/c1-6-26(4)38(43(60)51-36(44(61)62)22-29-24-46-31-17-11-10-16-30(29)31)52-39(56)32(18-12-13-19-45)48-42(59)35(23-37(54)55)50-40(57)33(20-25(2)3)49-41(58)34(47-27(5)53)21-28-14-8-7-9-15-28/h7-11,14-17,24-26,32-36,38,46H,6,12-13,18-23,45H2,1-5H3,(H,47,53)(H,48,59)(H,49,58)(H,50,57)(H,51,60)(H,52,56)(H,54,55)(H,61,62)/t26-,32-,33-,34+,35-,36-,38-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50231132
(CHEMBL313122)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C44H62N8O10/c1-6-26(4)38(43(60)48-32(18-12-13-19-45)39(56)51-36(44(61)62)22-29-24-46-31-17-11-10-16-30(29)31)52-42(59)35(23-37(54)55)50-40(57)33(20-25(2)3)49-41(58)34(47-27(5)53)21-28-14-8-7-9-15-28/h7-11,14-17,24-26,32-36,38,46H,6,12-13,18-23,45H2,1-5H3,(H,47,53)(H,48,60)(H,49,58)(H,50,57)(H,51,56)(H,52,59)(H,54,55)(H,61,62)/t26-,32-,33-,34+,35-,36-,38-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50001214
(3-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionyl...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C41H59N9O10/c1-8-22(5)34(39(57)48-32(41(59)60)15-25-18-43-28-13-11-10-12-27(25)28)50-40(58)35(23(6)9-2)49-38(56)31(17-33(52)53)47-36(54)29(14-21(3)4)46-37(55)30(45-24(7)51)16-26-19-42-20-44-26/h10-13,18-23,29-32,34-35,43H,8-9,14-17H2,1-7H3,(H,42,44)(H,45,51)(H,46,55)(H,47,54)(H,48,57)(H,49,56)(H,50,58)(H,52,53)(H,59,60)/t22-,23-,29-,30-,31-,32-,34-,35-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 5.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(RAT) | BDBM50231138
(CHEMBL3350293)Show SMILES CC[C@@H](C)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C41H59N9O10/c1-8-22(5)34(39(57)48-32(41(59)60)15-25-18-43-28-13-11-10-12-27(25)28)50-40(58)35(23(6)9-2)49-38(56)31(17-33(52)53)47-36(54)29(14-21(3)4)46-37(55)30(45-24(7)51)16-26-19-42-20-44-26/h10-13,18-23,29-32,34-35,43H,8-9,14-17H2,1-7H3,(H,42,44)(H,45,51)(H,46,55)(H,47,54)(H,48,57)(H,49,56)(H,50,58)(H,52,53)(H,59,60)/t22-,23+,29-,30-,31-,32-,34-,35+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.69E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description
Binding affinity against Endothelin receptor from rat heart ventricle |
J Med Chem 36: 2585-94 (1993)
BindingDB Entry DOI: 10.7270/Q2V69K6K |
More data for this
Ligand-Target Pair | |
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