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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for UniProtKB: P35439   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1/2B


(RAT-Mus musculus)		BDBM50446782
PNG
(CHEMBL3114672)
Show SMILES COc1cc(cc(c1O)[N+]([O-])=O)C(=O)P(O)(O)CC[C@H](N)C(O)=O |r|
Show InChI InChI=1S/C12H17N2O9P/c1-23-9-5-6(4-8(10(9)15)14(19)20)12(18)24(21,22)3-2-7(13)11(16)17/h4-5,7,15,21-22,24H,2-3,13H2,1H3,(H,16,17)/t7-/m0/s1
PDB

UniProtKB/SwissProt

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AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.30E+6n/an/an/an/an/an/a



Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques , CNRS UMR 8601, Université Paris Descartes, Sorbonne Paris Cité , 45 rue des Saints-Pères , 75270 Paris Cedex 06 , France.

Curated by ChEMBL


Assay Description
Antagonist activity at rat GluN1a/mouse GluN2B receptors expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glucine induced cu...

J Med Chem 61: 1969-1989 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01438
BindingDB Entry DOI: 10.7270/Q2DZ0BR0
More data for this
Ligand-Target Pair